ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	123/763	423/7206	7.44892484558e-28
ko05033	Nicotine addiction	40/763	56/7206	3.07364328162e-27
ko04724	Glutamatergic synapse	63/763	152/7206	1.5886553981e-23
ko04721	Synaptic vesicle cycle	44/763	80/7206	6.95917787464e-23
ko04728	Dopaminergic synapse	60/763	185/7206	2.62909127101e-16
ko05032	Morphine addiction	44/763	110/7206	4.69801820232e-16
ko04727	GABAergic synapse	42/763	110/7206	1.55268554241e-14
ko04723	Retrograde endocannabinoid signaling	52/763	175/7206	1.40011988318e-12
ko04725	Cholinergic synapse	48/763	160/7206	7.16610081476e-12
ko04713	Circadian entrainment	43/763	136/7206	1.33989710398e-11
ko04024	cAMP signaling pathway	64/763	279/7206	1.02567090236e-09
ko04911	Insulin secretion	35/763	117/7206	5.78726730274e-09
ko04726	Serotonergic synapse	37/763	137/7206	4.43262994272e-08
ko04744	Phototransduction	16/763	36/7206	2.03331767895e-07
ko05030	Cocaine addiction	24/763	73/7206	2.07924981088e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	24/763	74/7206	2.77458079446e-07
ko05031	Amphetamine addiction	27/763	91/7206	3.88907664537e-07
ko03040	Spliceosome	1/763	145/7206	3.30067615908e-06
ko04514	Cell adhesion molecules (CAMs)	32/763	130/7206	3.766141119e-06
ko04966	Collecting duct acid secretion	12/763	26/7206	4.3178568263e-06
ko05203	Viral carcinogenesis	9/763	277/7206	5.93814262571e-06
ko04261	Adrenergic signaling in cardiomyocytes	43/763	205/7206	8.52582964793e-06
ko04742	Taste transduction	19/763	61/7206	9.45980258662e-06
ko04060	Cytokine-cytokine receptor interaction	4/763	191/7206	1.18173870034e-05
ko04921	Oxytocin signaling pathway	43/763	209/7206	1.69389866055e-05
ko04010	MAPK signaling pathway	58/763	321/7206	3.69044354514e-05
ko04360	Axon guidance	45/763	233/7206	5.06794333983e-05
ko04720	Long-term potentiation	24/763	99/7206	8.6724070954e-05
ko04020	Calcium signaling pathway	49/763	265/7206	9.1146999531e-05
ko05164	Influenza A	4/763	167/7206	0.000101866004802
ko05168	Herpes simplex infection	5/763	182/7206	0.00012046628707
ko04970	Salivary secretion	23/763	95/7206	0.000126620297253
ko04621	NOD-like receptor signaling pathway	4/763	157/7206	0.000203797704731
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/763	14/7206	0.000255287012602
ko04120	Ubiquitin mediated proteolysis	3/763	138/7206	0.000364051538057
ko05205	Proteoglycans in cancer	12/763	271/7206	0.000375043072175
ko05322	Systemic lupus erythematosus	4/763	151/7206	0.000415835538256
ko03013	RNA transport	5/763	166/7206	0.000471399948365
ko04972	Pancreatic secretion	24/763	111/7206	0.000521123623703
ko04730	Long-term depression	18/763	78/7206	0.00120921426046
ko04141	Protein processing in endoplasmic reticulum	7/763	184/7206	0.00139891534689
ko04964	Proximal tubule bicarbonate reclamation	9/763	29/7206	0.00226152857028
ko03008	Ribosome biogenesis in eukaryotes	1/763	79/7206	0.00267342598296
ko05110	Vibrio cholerae infection	15/763	63/7206	0.00277512478595
ko04260	Cardiac muscle contraction	20/763	98/7206	0.00411129609858
ko04612	Antigen processing and presentation	1/763	77/7206	0.00415950038178
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/763	182/7206	0.00457926659604
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/763	79/7206	0.00463103923247
ko05166	HTLV-I infection	17/763	292/7206	0.00478620543576
ko05161	Hepatitis B	8/763	173/7206	0.00804782039352
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/763	59/7206	0.00893784484845
ko05120	Epithelial cell signaling in Helicobacter pylori infection	18/763	92/7206	0.00936103639818
ko05169	Epstein-Barr virus infection	11/763	206/7206	0.0110058360804
ko04064	NF-kappa B signaling pathway	3/763	96/7206	0.0115576569629
ko00240	Pyrimidine metabolism	4/763	110/7206	0.0119778844117
ko00561	Glycerolipid metabolism	1/763	63/7206	0.0124464098296
ko04640	Hematopoietic cell lineage	1/763	64/7206	0.0126119192483
ko04072	Phospholipase D signaling pathway	32/763	197/7206	0.0131303547486
ko04140	Autophagy - animal	8/763	164/7206	0.0140230743227
ko04391	Hippo signaling pathway - fly	17/763	90/7206	0.0151111440674
ko05162	Measles	5/763	120/7206	0.0162680942391
ko04014	Ras signaling pathway	42/763	279/7206	0.0169809617713
ko00330	Arginine and proline metabolism	1/763	61/7206	0.0188675936389
ko04971	Gastric acid secretion	18/763	98/7206	0.0190674380864
ko04540	Gap junction	22/763	128/7206	0.0197282995981
ko04110	Cell cycle	7/763	145/7206	0.0197798189925
ko00310	Lysine degradation	2/763	73/7206	0.021319572959
ko05140	Leishmaniasis	2/763	75/7206	0.0216488742786
ko05016	Huntington's disease	13/763	215/7206	0.0243741454664
ko04217	Necroptosis	10/763	178/7206	0.0260697510869
ko04976	Bile secretion	15/763	80/7206	0.0261780122345
ko00480	Glutathione metabolism	1/763	55/7206	0.0266622025311
ko05321	Inflammatory bowel disease (IBD)	1/763	56/7206	0.0269060632325
ko03018	RNA degradation	3/763	84/7206	0.0313959605025
ko04022	cGMP-PKG signaling pathway	33/763	216/7206	0.0319401210585
ko05418	Fluid shear stress and atherosclerosis	10/763	173/7206	0.0335770707242
ko04925	Aldosterone synthesis and secretion	18/763	105/7206	0.03641515246
ko04211	Longevity regulating pathway	6/763	123/7206	0.0374210568467
ko04611	Platelet activation	9/763	163/7206	0.0379923173348
ko00590	Arachidonic acid metabolism	1/763	52/7206	0.0392112165886
ko04630	Jak-STAT signaling pathway	7/763	132/7206	0.0451427874348
ko05200	Pathways in cancer	39/763	492/7206	0.0482152551025