ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	125/739	423/7206	1.80313741357e-30
ko05033	Nicotine addiction	38/739	56/7206	3.81928390373e-25
ko04724	Glutamatergic synapse	63/739	152/7206	2.69220491442e-24
ko04728	Dopaminergic synapse	67/739	185/7206	7.70654720687e-22
ko05032	Morphine addiction	47/739	110/7206	4.93997652602e-19
ko04727	GABAergic synapse	46/739	110/7206	3.3739357e-18
ko04713	Circadian entrainment	50/739	136/7206	7.28652745773e-17
ko04024	cAMP signaling pathway	74/739	279/7206	2.84533644176e-15
ko04723	Retrograde endocannabinoid signaling	55/739	175/7206	5.56885123693e-15
ko04725	Cholinergic synapse	52/739	160/7206	6.76329451188e-15
ko04721	Synaptic vesicle cycle	35/739	80/7206	7.31239875558e-15
ko04911	Insulin secretion	39/739	117/7206	7.33814150672e-12
ko04744	Phototransduction	19/739	36/7206	2.06026714733e-10
ko04726	Serotonergic synapse	40/739	137/7206	3.96163547605e-10
ko05031	Amphetamine addiction	31/739	91/7206	5.84396397438e-10
ko04020	Calcium signaling pathway	58/739	265/7206	1.23607972244e-08
ko04921	Oxytocin signaling pathway	49/739	209/7206	1.86246572384e-08
ko05030	Cocaine addiction	25/739	73/7206	2.43684280687e-08
ko04261	Adrenergic signaling in cardiomyocytes	47/739	205/7206	6.99547449879e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	24/739	74/7206	1.51848504579e-07
ko04720	Long-term potentiation	28/739	99/7206	3.65488266428e-07
ko04742	Taste transduction	20/739	61/7206	1.36419286405e-06
ko04360	Axon guidance	48/739	233/7206	1.6172581401e-06
ko05203	Viral carcinogenesis	8/739	277/7206	3.98454144148e-06
ko03040	Spliceosome	1/739	145/7206	4.93373137294e-06
ko04514	Cell adhesion molecules (CAMs)	31/739	130/7206	5.63854810491e-06
ko04010	MAPK signaling pathway	59/739	321/7206	7.33682761907e-06
ko04970	Salivary secretion	24/739	95/7206	2.08109503873e-05
ko04060	Cytokine-cytokine receptor interaction	5/739	191/7206	8.57508233398e-05
ko05322	Systemic lupus erythematosus	3/739	151/7206	0.000117373445272
ko03013	RNA transport	4/739	166/7206	0.000146235375363
ko04022	cGMP-PKG signaling pathway	40/739	216/7206	0.000218496984231
ko04730	Long-term depression	19/739	78/7206	0.000249001775972
ko04745	Phototransduction - fly	12/739	38/7206	0.000269949711777
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/739	79/7206	0.000481697250502
ko04120	Ubiquitin mediated proteolysis	3/739	138/7206	0.000524903870971
ko05168	Herpes simplex infection	6/739	182/7206	0.000714966190117
ko04925	Aldosterone synthesis and secretion	22/739	105/7206	0.00094985486795
ko04971	Gastric acid secretion	21/739	98/7206	0.00106011068445
ko04621	NOD-like receptor signaling pathway	5/739	157/7206	0.00128584545172
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/739	14/7206	0.00166093816759
ko04141	Protein processing in endoplasmic reticulum	7/739	184/7206	0.00188123077668
ko04260	Cardiac muscle contraction	20/739	98/7206	0.00220967169471
ko04972	Pancreatic secretion	22/739	111/7206	0.00227388566882
ko05164	Influenza A	6/739	167/7206	0.00264322631123
ko03008	Ribosome biogenesis in eukaryotes	1/739	79/7206	0.00414692369984
ko05166	HTLV-I infection	16/739	292/7206	0.00416924541187
ko04740	Olfactory transduction	17/739	80/7206	0.00431778728856
ko04214	Apoptosis - fly	1/739	72/7206	0.00583951924733
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/739	182/7206	0.00605418631526
ko00240	Pyrimidine metabolism	3/739	110/7206	0.00618295750822
ko04014	Ras signaling pathway	43/739	279/7206	0.00626415888719
ko05169	Epstein-Barr virus infection	10/739	206/7206	0.00704029091439
ko04964	Proximal tubule bicarbonate reclamation	8/739	29/7206	0.00714401464363
ko04146	Peroxisome	2/739	89/7206	0.00745728782993
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/739	59/7206	0.00748017180457
ko05205	Proteoglycans in cancer	15/739	271/7206	0.0076197661037
ko04350	TGF-beta signaling pathway	3/739	103/7206	0.00832452601816
ko04640	Hematopoietic cell lineage	1/739	64/7206	0.0125909321155
ko04966	Collecting duct acid secretion	7/739	26/7206	0.0133741041083
ko04137	Mitophagy - animal	2/739	82/7206	0.0155239020932
ko04064	NF-kappa B signaling pathway	3/739	96/7206	0.0164864424479
ko00561	Glycerolipid metabolism	1/739	63/7206	0.0190844941993
ko04612	Antigen processing and presentation	2/739	77/7206	0.021730590564
ko04930	Type II diabetes mellitus	11/739	54/7206	0.0220897573155
ko05162	Measles	5/739	120/7206	0.0222611430263
ko05161	Hepatitis B	9/739	173/7206	0.0223069731637
ko04072	Phospholipase D signaling pathway	30/739	197/7206	0.0235992401707
ko00512	Mucin type O-glycan biosynthesis	7/739	29/7206	0.0242353427644
ko04626	Plant-pathogen interaction	5/739	18/7206	0.0308839597315
ko04391	Hippo signaling pathway - fly	16/739	90/7206	0.0332431390637
ko04973	Carbohydrate digestion and absorption	9/739	42/7206	0.034551515501
ko05016	Huntington's disease	13/739	215/7206	0.0392952317511
ko04915	Estrogen signaling pathway	21/739	131/7206	0.0400183322098
ko00480	Glutathione metabolism	1/739	55/7206	0.0405713065494
ko00564	Glycerophospholipid metabolism	4/739	99/7206	0.0431797600763
ko04218	Cellular senescence	10/739	177/7206	0.04362585744
ko03018	RNA degradation	3/739	84/7206	0.0443245358862