ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 30/321 79/7206 5.93158758052e-21 ko04974 Protein digestion and absorption 21/321 96/7206 8.20455489577e-10 ko04976 Bile secretion 19/321 80/7206 1.21915691649e-09 ko00983 Drug metabolism - other enzymes 12/321 42/7206 1.64792246203e-07 ko00380 Tryptophan metabolism 12/321 50/7206 1.31097588105e-06 ko04975 Fat digestion and absorption 10/321 35/7206 1.81633883427e-06 ko04977 Vitamin digestion and absorption 8/321 22/7206 2.6289302445e-06 ko04614 Renin-angiotensin system 7/321 18/7206 6.78720368944e-06 ko04978 Mineral absorption 10/321 40/7206 6.87292214402e-06 ko00350 Tyrosine metabolism 9/321 33/7206 9.23022401339e-06 ko05150 Staphylococcus aureus infection 9/321 36/7206 2.00149426953e-05 ko04972 Pancreatic secretion 16/321 111/7206 2.86229837257e-05 ko02010 ABC transporters 9/321 39/7206 4.00271043145e-05 ko00830 Retinol metabolism 9/321 42/7206 7.48355339106e-05 ko04144 Endocytosis 3/321 342/7206 0.000221676858876 ko05204 Chemical carcinogenesis 9/321 48/7206 0.000222328320663 ko00260 Glycine, serine and threonine metabolism 9/321 48/7206 0.000222328320663 ko05166 HTLV-I infection 2/321 292/7206 0.000239496155948 ko00643 Styrene degradation 3/321 4/7206 0.000338828759655 ko00140 Steroid hormone biosynthesis 8/321 41/7206 0.000374202526843 ko00340 Histidine metabolism 6/321 25/7206 0.000643125691024 ko00360 Phenylalanine metabolism 5/321 17/7206 0.00067537495762 ko00232 Caffeine metabolism 3/321 5/7206 0.000819085281794 ko03320 PPAR signaling pathway 10/321 69/7206 0.000874333769165 ko00982 Drug metabolism - cytochrome P450 7/321 37/7206 0.00105716268708 ko05016 Huntington's disease 1/321 215/7206 0.00110211027966 ko00250 Alanine, aspartate and glutamate metabolism 7/321 38/7206 0.00124727943371 ko00120 Primary bile acid biosynthesis 5/321 20/7206 0.00151550133944 ko00980 Metabolism of xenobiotics by cytochrome P450 7/321 40/7206 0.00170709953126 ko04010 MAPK signaling pathway 4/321 321/7206 0.00203260961727 ko05200 Pathways in cancer 9/321 492/7206 0.00203787226706 ko00591 Linoleic acid metabolism 5/321 22/7206 0.0023922025524 ko00480 Glutathione metabolism 8/321 55/7206 0.00277382626424 ko04360 Axon guidance 2/321 233/7206 0.0031146502881 ko04141 Protein processing in endoplasmic reticulum 1/321 184/7206 0.00335631454837 ko04390 Hippo signaling pathway 1/321 188/7206 0.00342080722732 ko04217 Necroptosis 1/321 178/7206 0.00493531982312 ko04310 Wnt signaling pathway 1/321 181/7206 0.00508880596295 ko00590 Arachidonic acid metabolism 7/321 52/7206 0.00776508911086 ko00950 Isoquinoline alkaloid biosynthesis 3/321 10/7206 0.0083185730491 ko04964 Proximal tubule bicarbonate reclamation 5/321 29/7206 0.00835814000117 ko04973 Carbohydrate digestion and absorption 6/321 42/7206 0.010087126248 ko00965 Betalain biosynthesis 2/321 4/7206 0.011181485413 ko00100 Steroid biosynthesis 4/321 21/7206 0.012677361408 ko00053 Ascorbate and aldarate metabolism 4/321 22/7206 0.0149629522648 ko05012 Parkinson's disease 1/321 155/7206 0.0156709653739 ko00270 Cysteine and methionine metabolism 6/321 47/7206 0.0171591790634 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/321 5/7206 0.0180897521673 ko00410 beta-Alanine metabolism 5/321 35/7206 0.0183914404744 ko00770 Pantothenate and CoA biosynthesis 3/321 14/7206 0.02211103197 ko04110 Cell cycle 1/321 145/7206 0.0223208073114 ko05161 Hepatitis B 2/321 173/7206 0.0248256263471 ko05203 Viral carcinogenesis 5/321 277/7206 0.0250729253723 ko00630 Glyoxylate and dicarboxylate metabolism 5/321 38/7206 0.025529113414 ko00362 Benzoate degradation 2/321 6/7206 0.026342545495 ko00650 Butanoate metabolism 4/321 26/7206 0.0266107519584 ko04380 Osteoclast differentiation 1/321 134/7206 0.031530732466 ko04550 Signaling pathways regulating pluripotency of stem cells 2/321 165/7206 0.0348042646688 ko04062 Chemokine signaling pathway 3/321 201/7206 0.0358952509126 ko04261 Adrenergic signaling in cardiomyocytes 3/321 205/7206 0.0367020576837 ko05169 Epstein-Barr virus infection 3/321 206/7206 0.0370128515278 ko01523 Antifolate resistance 4/321 30/7206 0.0424898369192 ko00901 Indole alkaloid biosynthesis 1/321 1/7206 0.0445462114904 ko00401 Novobiocin biosynthesis 1/321 1/7206 0.0445462114904 ko05162 Measles 1/321 120/7206 0.0445967016073 ko04668 TNF signaling pathway 1/321 120/7206 0.0445967016073 ko04666 Fc gamma R-mediated phagocytosis 1/321 122/7206 0.0446514831743 ko04660 T cell receptor signaling pathway 1/321 124/7206 0.045031646412 ko04621 NOD-like receptor signaling pathway 2/321 157/7206 0.0487375535132 ko04722 Neurotrophin signaling pathway 2/321 160/7206 0.0494426275969 ko00592 alpha-Linolenic acid metabolism 3/321 19/7206 0.0499943964922