ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	164/929	423/7206	2.62443815912e-44
ko05033	Nicotine addiction	44/929	56/7206	3.44784762834e-29
ko04724	Glutamatergic synapse	75/929	152/7206	2.78334062855e-28
ko04727	GABAergic synapse	56/929	110/7206	3.29279575999e-22
ko05032	Morphine addiction	56/929	110/7206	3.29279575999e-22
ko04728	Dopaminergic synapse	71/929	185/7206	6.03710595186e-19
ko04723	Retrograde endocannabinoid signaling	67/929	175/7206	7.18784997088e-18
ko04725	Cholinergic synapse	59/929	160/7206	5.39732056498e-15
ko04713	Circadian entrainment	53/929	136/7206	9.4882716846e-15
ko04911	Insulin secretion	48/929	117/7206	1.73225140745e-14
ko04721	Synaptic vesicle cycle	37/929	80/7206	2.12900067649e-13
ko04726	Serotonergic synapse	51/929	137/7206	2.6012705183e-13
ko04024	cAMP signaling pathway	80/929	279/7206	8.65690071806e-13
ko04020	Calcium signaling pathway	75/929	265/7206	9.05280811048e-12
ko04742	Taste transduction	29/929	61/7206	3.76721131886e-11
ko04261	Adrenergic signaling in cardiomyocytes	58/929	205/7206	2.33308692242e-09
ko05031	Amphetamine addiction	33/929	91/7206	9.74742080316e-09
ko04921	Oxytocin signaling pathway	57/929	209/7206	2.20189762997e-08
ko05030	Cocaine addiction	28/929	73/7206	3.1633086795e-08
ko03040	Spliceosome	1/929	145/7206	5.77688605309e-08
ko04744	Phototransduction	18/929	36/7206	7.64657837312e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	26/929	74/7206	7.40540719022e-07
ko04720	Long-term potentiation	31/929	99/7206	1.19119680999e-06
ko04970	Salivary secretion	30/929	95/7206	1.44963977335e-06
ko05322	Systemic lupus erythematosus	3/929	151/7206	3.23672708369e-06
ko04514	Cell adhesion molecules (CAMs)	36/929	130/7206	7.23860950002e-06
ko03013	RNA transport	5/929	166/7206	1.71637176901e-05
ko04972	Pancreatic secretion	31/929	111/7206	2.01143129963e-05
ko04010	MAPK signaling pathway	68/929	321/7206	2.49761175936e-05
ko05203	Viral carcinogenesis	15/929	277/7206	4.87154663286e-05
ko04072	Phospholipase D signaling pathway	46/929	197/7206	5.14582527033e-05
ko05164	Influenza A	6/929	167/7206	5.64040693071e-05
ko04925	Aldosterone synthesis and secretion	28/929	105/7206	0.000167152200914
ko05168	Herpes simplex infection	8/929	182/7206	0.000180532896322
ko04260	Cardiac muscle contraction	26/929	98/7206	0.000217070114708
ko04060	Cytokine-cytokine receptor interaction	9/929	191/7206	0.000256346066903
ko04022	cGMP-PKG signaling pathway	47/929	216/7206	0.000264069946615
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/929	79/7206	0.000304157566548
ko04360	Axon guidance	49/929	233/7206	0.000447442689737
ko04971	Gastric acid secretion	25/929	98/7206	0.000648466366535
ko04730	Long-term depression	21/929	78/7206	0.000894056309876
ko04120	Ubiquitin mediated proteolysis	6/929	138/7206	0.00118089926539
ko04014	Ras signaling pathway	54/929	279/7206	0.00184157492964
ko05205	Proteoglycans in cancer	19/929	271/7206	0.00219175442086
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/929	59/7206	0.00281141540882
ko03008	Ribosome biogenesis in eukaryotes	2/929	79/7206	0.00336390336531
ko04141	Protein processing in endoplasmic reticulum	11/929	184/7206	0.00347651043471
ko04540	Gap junction	28/929	128/7206	0.00467791353323
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/929	14/7206	0.00540514163664
ko04915	Estrogen signaling pathway	28/929	131/7206	0.00553520152023
ko05162	Measles	6/929	120/7206	0.00580037473556
ko05414	Dilated cardiomyopathy	25/929	112/7206	0.00620169274205
ko04930	Type II diabetes mellitus	14/929	54/7206	0.00765109481248
ko04918	Thyroid hormone synthesis	20/929	86/7206	0.00844686378477
ko04964	Proximal tubule bicarbonate reclamation	9/929	29/7206	0.00854646074921
ko04070	Phosphatidylinositol signaling system	24/929	112/7206	0.0100708238331
ko04610	Complement and coagulation cascades	3/929	79/7206	0.0106242846774
ko00590	Arachidonic acid metabolism	1/929	52/7206	0.0114494266012
ko04217	Necroptosis	12/929	178/7206	0.0121553184862
ko05016	Huntington's disease	16/929	215/7206	0.012960647371
ko00561	Glycerolipid metabolism	2/929	63/7206	0.0138249145587
ko00240	Pyrimidine metabolism	6/929	110/7206	0.014536846515
ko05140	Leishmaniasis	3/929	75/7206	0.014966638737
ko04612	Antigen processing and presentation	3/929	77/7206	0.0152487579482
ko05133	Pertussis	4/929	87/7206	0.0152902974967
ko04146	Peroxisome	4/929	89/7206	0.0156413071743
ko04740	Olfactory transduction	18/929	80/7206	0.0171829765684
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/929	182/7206	0.0180595784682
ko04270	Vascular smooth muscle contraction	30/929	154/7206	0.0200609203631
ko04710	Circadian rhythm	11/929	43/7206	0.0204010040653
ko00310	Lysine degradation	3/929	73/7206	0.0211489907199
ko04621	NOD-like receptor signaling pathway	11/929	157/7206	0.0221623777889
ko04071	Sphingolipid signaling pathway	31/929	162/7206	0.0233930330909
ko05144	Malaria	1/929	45/7206	0.0248596746281
ko00071	Fatty acid degradation	1/929	45/7206	0.0248596746281
ko00620	Pyruvate metabolism	1/929	46/7206	0.0250776381925
ko03420	Nucleotide excision repair	1/929	46/7206	0.0250776381925
ko05169	Epstein-Barr virus infection	16/929	206/7206	0.0261448001417
ko03320	PPAR signaling pathway	3/929	69/7206	0.029423304216
ko04110	Cell cycle	10/929	145/7206	0.0321892840366
ko04611	Platelet activation	12/929	163/7206	0.0327207048535
ko04924	Renin secretion	18/929	86/7206	0.0338898953243
ko04630	Jak-STAT signaling pathway	9/929	132/7206	0.0352093770388
ko04960	Aldosterone-regulated sodium reabsorption	10/929	41/7206	0.0353951379895
ko04142	Lysosome	11/929	151/7206	0.0365293526777
ko00565	Ether lipid metabolism	1/929	42/7206	0.0365876989587
ko03022	Basal transcription factors	1/929	44/7206	0.0381390677063
ko04216	Ferroptosis	1/929	44/7206	0.0381390677063
ko04976	Bile secretion	17/929	80/7206	0.0415787370303
ko04916	Melanogenesis	27/929	142/7206	0.0416703237249
ko01200	Carbon metabolism	9/929	128/7206	0.0454768702209
ko04962	Vasopressin-regulated water reabsorption	13/929	58/7206	0.0455708455144
ko05410	Hypertrophic cardiomyopathy (HCM)	20/929	100/7206	0.0486658707508