ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	154/800	423/7206	3.59614546361e-46
ko04724	Glutamatergic synapse	77/800	152/7206	1.38031953966e-34
ko05033	Nicotine addiction	43/800	56/7206	1.47266111682e-30
ko04727	GABAergic synapse	56/800	110/7206	1.69332595257e-25
ko05032	Morphine addiction	55/800	110/7206	1.47698994526e-24
ko04723	Retrograde endocannabinoid signaling	67/800	175/7206	1.87574638259e-21
ko04728	Dopaminergic synapse	68/800	185/7206	1.32709402275e-20
ko04713	Circadian entrainment	52/800	136/7206	7.53266228625e-17
ko04725	Cholinergic synapse	57/800	160/7206	1.05037025e-16
ko04726	Serotonergic synapse	49/800	137/7206	1.34340746981e-14
ko04024	cAMP signaling pathway	75/800	279/7206	6.50531777758e-14
ko04742	Taste transduction	30/800	61/7206	1.09565872543e-13
ko04911	Insulin secretion	43/800	117/7206	1.96294423033e-13
ko04721	Synaptic vesicle cycle	33/800	80/7206	3.19767047867e-12
ko04020	Calcium signaling pathway	68/800	265/7206	1.10637578975e-11
ko04744	Phototransduction	20/800	36/7206	8.35220114278e-11
ko05031	Amphetamine addiction	32/800	91/7206	9.31307553943e-10
ko04921	Oxytocin signaling pathway	53/800	209/7206	3.89370159375e-09
ko04261	Adrenergic signaling in cardiomyocytes	52/800	205/7206	5.52098316345e-09
ko05030	Cocaine addiction	26/800	73/7206	2.62465806467e-08
ko04720	Long-term potentiation	31/800	99/7206	4.0060593884e-08
ko04514	Cell adhesion molecules (CAMs)	36/800	130/7206	1.13211187121e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	24/800	74/7206	6.69456179526e-07
ko03040	Spliceosome	1/800	145/7206	1.35006929395e-06
ko04970	Salivary secretion	26/800	95/7206	8.31161826503e-06
ko04740	Olfactory transduction	23/800	80/7206	1.13421827793e-05
ko04972	Pancreatic secretion	28/800	111/7206	2.2191463797e-05
ko05203	Viral carcinogenesis	11/800	277/7206	2.29837231056e-05
ko04010	MAPK signaling pathway	61/800	321/7206	2.36484584063e-05
ko05322	Systemic lupus erythematosus	3/800	151/7206	3.62877691895e-05
ko05164	Influenza A	4/800	167/7206	4.80512127843e-05
ko04260	Cardiac muscle contraction	25/800	98/7206	5.46390752912e-05
ko04971	Gastric acid secretion	25/800	98/7206	5.46390752912e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/800	79/7206	9.64858964417e-05
ko03013	RNA transport	5/800	166/7206	0.000231489981975
ko04022	cGMP-PKG signaling pathway	42/800	216/7206	0.000243492319494
ko04925	Aldosterone synthesis and secretion	24/800	105/7206	0.00045246730056
ko05168	Herpes simplex infection	7/800	182/7206	0.000708490476804
ko04072	Phospholipase D signaling pathway	38/800	197/7206	0.000736489780478
ko04120	Ubiquitin mediated proteolysis	4/800	138/7206	0.000836787262784
ko04110	Cell cycle	5/800	145/7206	0.00123214589979
ko04610	Complement and coagulation cascades	1/800	79/7206	0.00176171002398
ko04745	Phototransduction - fly	11/800	38/7206	0.0021077629466
ko04730	Long-term depression	18/800	78/7206	0.00288222043361
ko05162	Measles	4/800	120/7206	0.00313905574291
ko04964	Proximal tubule bicarbonate reclamation	9/800	29/7206	0.00314102981147
ko04218	Cellular senescence	8/800	177/7206	0.00331117951324
ko05205	Proteoglycans in cancer	16/800	271/7206	0.0040668404142
ko04141	Protein processing in endoplasmic reticulum	9/800	184/7206	0.00414643475111
ko05166	HTLV-I infection	18/800	292/7206	0.00424759228917
ko05161	Hepatitis B	8/800	173/7206	0.00443807540335
ko05218	Melanoma	2/800	85/7206	0.00497263423371
ko04750	Inflammatory mediator regulation of TRP channels	24/800	122/7206	0.00510645020423
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/800	59/7206	0.00526703994007
ko04360	Axon guidance	40/800	233/7206	0.00549627511714
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/800	182/7206	0.00558079576429
ko05169	Epstein-Barr virus infection	11/800	206/7206	0.00648608203085
ko04930	Type II diabetes mellitus	13/800	54/7206	0.00685119975044
ko04060	Cytokine-cytokine receptor interaction	10/800	191/7206	0.00686748533297
ko04611	Platelet activation	8/800	163/7206	0.00777359677056
ko00240	Pyrimidine metabolism	4/800	110/7206	0.00856908358396
ko04014	Ras signaling pathway	45/800	279/7206	0.00856969977545
ko05215	Prostate cancer	4/800	111/7206	0.00871234665734
ko05414	Dilated cardiomyopathy	22/800	112/7206	0.0089333267515
ko04612	Antigen processing and presentation	2/800	77/7206	0.0102764679685
ko03008	Ribosome biogenesis in eukaryotes	2/800	79/7206	0.0104314467171
ko04630	Jak-STAT signaling pathway	6/800	132/7206	0.0114449703028
ko04974	Protein digestion and absorption	19/800	96/7206	0.0126762293563
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/800	14/7206	0.0141577527668
ko01200	Carbon metabolism	6/800	128/7206	0.0154207434624
ko04140	Autophagy - animal	9/800	164/7206	0.016687659892
ko04142	Lysosome	8/800	151/7206	0.0180834622206
ko05034	Alcoholism	38/800	238/7206	0.0204169545815
ko04916	Melanogenesis	25/800	142/7206	0.0206123314325
ko04214	Apoptosis - fly	2/800	72/7206	0.0215104092701
ko04540	Gap junction	23/800	128/7206	0.0217223154716
ko03018	RNA degradation	3/800	84/7206	0.0222440082237
ko05220	Chronic myeloid leukemia	3/800	85/7206	0.0224392419673
ko04150	mTOR signaling pathway	11/800	184/7206	0.0233245005218
ko05016	Huntington's disease	14/800	215/7206	0.0272489839897
ko00480	Glutathione metabolism	1/800	55/7206	0.0276098221251
ko04621	NOD-like receptor signaling pathway	9/800	157/7206	0.0283934446417
ko03320	PPAR signaling pathway	2/800	69/7206	0.0311780791573
ko05410	Hypertrophic cardiomyopathy (HCM)	18/800	100/7206	0.0357302889327
ko00380	Tryptophan metabolism	1/800	50/7206	0.038940536726
ko04960	Aldosterone-regulated sodium reabsorption	9/800	41/7206	0.0407508638356
ko04146	Peroxisome	4/800	89/7206	0.0416696529602
ko04145	Phagosome	10/800	162/7206	0.0425410970386
ko01524	Platinum drug resistance	3/800	76/7206	0.0428959533562
ko05130	Pathogenic Escherichia coli infection	3/800	77/7206	0.0431243695337
ko00190	Oxidative phosphorylation	7/800	127/7206	0.0448341508417
ko04973	Carbohydrate digestion and absorption	9/800	42/7206	0.0448648535367
ko04976	Bile secretion	15/800	80/7206	0.0458481331275
ko04915	Estrogen signaling pathway	22/800	131/7206	0.0477843706158
ko05418	Fluid shear stress and atherosclerosis	11/800	173/7206	0.0488592664734