ko pathway ratio_in_study ratio_in_pop p_value ko04621 NOD-like receptor signaling pathway 7/40 157/7206 2.07683316087e-05 ko04668 TNF signaling pathway 6/40 120/7206 4.54629021828e-05 ko05160 Hepatitis C 6/40 153/7206 0.000175548676 ko05100 Bacterial invasion of epithelial cells 5/40 99/7206 0.000198754334023 ko04620 Toll-like receptor signaling pathway 5/40 100/7206 0.000208368007682 ko04217 Necroptosis 6/40 178/7206 0.000398699418117 ko04810 Regulation of actin cytoskeleton 7/40 264/7206 0.000540299201763 ko01522 Endocrine resistance 5/40 124/7206 0.000565326690478 ko04072 Phospholipase D signaling pathway 6/40 197/7206 0.000683732964784 ko05131 Shigellosis 4/40 82/7206 0.00104247435838 ko05212 Pancreatic cancer 4/40 83/7206 0.00109089864234 ko04064 NF-kappa B signaling pathway 4/40 96/7206 0.00187248560674 ko01521 EGFR tyrosine kinase inhibitor resistance 4/40 106/7206 0.00269080250085 ko05152 Tuberculosis 5/40 187/7206 0.00351186817091 ko05167 Kaposi's sarcoma-associated herpesvirus infection 5/40 191/7206 0.00384551979 ko05162 Measles 4/40 120/7206 0.00420841677929 ko04666 Fc gamma R-mediated phagocytosis 4/40 122/7206 0.00446418340311 ko05213 Endometrial cancer 3/40 62/7206 0.0047781784629 ko04622 RIG-I-like receptor signaling pathway 3/40 62/7206 0.0047781784629 ko05200 Pathways in cancer 8/40 492/7206 0.00490797606874 ko05223 Non-small cell lung cancer 3/40 66/7206 0.00569357727991 ko04380 Osteoclast differentiation 4/40 134/7206 0.00622239628891 ko04933 AGE-RAGE signaling pathway in diabetic complications 4/40 135/7206 0.00638697188649 ko04214 Apoptosis - fly 3/40 72/7206 0.0072524188869 ko04919 Thyroid hormone signaling pathway 4/40 143/7206 0.00780919920246 ko01524 Platinum drug resistance 3/40 76/7206 0.00841919017267 ko05214 Glioma 3/40 79/7206 0.00936281637402 ko05230 Central carbon metabolism in cancer 3/40 81/7206 0.0100250034671 ko05218 Melanoma 3/40 85/7206 0.0114298081508 ko05210 Colorectal cancer 3/40 86/7206 0.0117979101532 ko04662 B cell receptor signaling pathway 3/40 88/7206 0.0125545529397 ko04320 Dorso-ventral axis formation 2/40 31/7206 0.0126210178161 ko00562 Inositol phosphate metabolism 3/40 89/7206 0.0129431349417 ko05161 Hepatitis B 4/40 173/7206 0.0149625407822 ko05224 Breast cancer 4/40 174/7206 0.0152540949818 ko04218 Cellular senescence 4/40 177/7206 0.0161503913304 ko04210 Apoptosis 4/40 180/7206 0.0170794295497 ko05146 Amoebiasis 3/40 99/7206 0.0172093189645 ko05168 Herpes simplex infection 4/40 182/7206 0.0177171568141 ko04015 Rap1 signaling pathway 5/40 278/7206 0.0179641673988 ko00524 Neomycin, kanamycin and gentamicin biosynthesis 1/40 4/7206 0.0220240722518 ko04012 ErbB signaling pathway 3/40 109/7206 0.0221757399981 ko04973 Carbohydrate digestion and absorption 2/40 42/7206 0.0224912502161 ko05215 Prostate cancer 3/40 111/7206 0.0232537297578 ko04070 Phosphatidylinositol signaling system 3/40 112/7206 0.023803334259 ko04013 MAPK signaling pathway - fly 3/40 115/7206 0.0254945915857 ko05169 Epstein-Barr virus infection 4/40 206/7206 0.0265512983988 ko04215 Apoptosis - multiple species 2/40 47/7206 0.0277522639914 ko05219 Bladder cancer 2/40 48/7206 0.028858644523 ko04750 Inflammatory mediator regulation of TRP channels 3/40 122/7206 0.0296882256522 ko04624 Toll and Imd signaling pathway 2/40 49/7206 0.0299825666051 ko04066 HIF-1 signaling pathway 3/40 123/7206 0.0303155330557 ko04660 T cell receptor signaling pathway 3/40 124/7206 0.0309498780993 ko05142 Chagas disease (American trypanosomiasis) 3/40 130/7206 0.0349033058893 ko04915 Estrogen signaling pathway 3/40 131/7206 0.0355866861485 ko04930 Type II diabetes mellitus 2/40 54/7206 0.0358577223973 ko05231 Choline metabolism in cancer 3/40 134/7206 0.0376785753838 ko05321 Inflammatory bowel disease (IBD) 2/40 56/7206 0.0383230713518 ko04144 Endocytosis 5/40 342/7206 0.0393734090144 ko04961 Endocrine and other factor-regulated calcium reabsorption 2/40 59/7206 0.0421394206622 ko00521 Streptomycin biosynthesis 1/40 8/7206 0.0435749502382 ko05221 Acute myeloid leukemia 2/40 63/7206 0.0474402812939