ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	104/622	423/7206	1.61238024749e-24
ko04744	Phototransduction	27/622	36/7206	4.95827699647e-22
ko05033	Nicotine addiction	32/622	56/7206	2.54034868335e-20
ko04727	GABAergic synapse	44/622	110/7206	1.76210303291e-19
ko04724	Glutamatergic synapse	51/622	152/7206	1.82509548214e-18
ko05032	Morphine addiction	41/622	110/7206	6.43861907477e-17
ko04713	Circadian entrainment	46/622	136/7206	6.50943886335e-17
ko04740	Olfactory transduction	31/622	80/7206	1.26182159817e-13
ko04723	Retrograde endocannabinoid signaling	48/622	175/7206	1.34834291355e-13
ko04726	Serotonergic synapse	37/622	137/7206	1.53159295681e-10
ko04728	Dopaminergic synapse	44/622	185/7206	2.60879944632e-10
ko04725	Cholinergic synapse	40/622	160/7206	3.53773963075e-10
ko04921	Oxytocin signaling pathway	46/622	209/7206	1.5596568666e-09
ko04911	Insulin secretion	31/622	117/7206	8.04719937102e-09
ko04972	Pancreatic secretion	29/622	111/7206	3.4601049063e-08
ko04020	Calcium signaling pathway	51/622	265/7206	3.4726908638e-08
ko04970	Salivary secretion	25/622	95/7206	2.6426184236e-07
ko04742	Taste transduction	19/622	61/7206	4.33293822979e-07
ko04971	Gastric acid secretion	25/622	98/7206	5.03609926025e-07
ko04024	cAMP signaling pathway	50/622	279/7206	5.47632388646e-07
ko04721	Synaptic vesicle cycle	22/622	80/7206	6.08109885699e-07
ko05031	Amphetamine addiction	23/622	91/7206	1.71712419218e-06
ko05203	Viral carcinogenesis	5/622	277/7206	1.92151931046e-06
ko04720	Long-term potentiation	24/622	99/7206	2.29281059376e-06
ko05164	Influenza A	1/622	167/7206	8.42399545823e-06
ko04261	Adrenergic signaling in cardiomyocytes	37/622	205/7206	1.21185955469e-05
ko05166	HTLV-I infection	7/622	292/7206	1.56926027488e-05
ko04974	Protein digestion and absorption	22/622	96/7206	1.59163917779e-05
ko04976	Bile secretion	19/622	80/7206	3.53046270133e-05
ko04745	Phototransduction - fly	12/622	38/7206	5.1064279861e-05
ko04925	Aldosterone synthesis and secretion	22/622	105/7206	6.91656649661e-05
ko04730	Long-term depression	18/622	78/7206	8.45882214886e-05
ko04120	Ubiquitin mediated proteolysis	1/622	138/7206	8.80356589888e-05
ko05030	Cocaine addiction	17/622	73/7206	0.000117476865907
ko05169	Epstein-Barr virus infection	4/622	206/7206	0.000119223309352
ko05168	Herpes simplex infection	3/622	182/7206	0.000134135520916
ko05322	Systemic lupus erythematosus	2/622	151/7206	0.000202175112081
ko05161	Hepatitis B	3/622	173/7206	0.000279145139582
ko04550	Signaling pathways regulating pluripotency of stem cells	3/622	165/7206	0.000384279621069
ko03013	RNA transport	3/622	166/7206	0.000385509604205
ko05205	Proteoglycans in cancer	9/622	271/7206	0.000582075612674
ko04710	Circadian rhythm	11/622	43/7206	0.000803730884645
ko05224	Breast cancer	4/622	174/7206	0.000910431359039
ko05215	Prostate cancer	1/622	111/7206	0.000925913472829
ko04218	Cellular senescence	4/622	177/7206	0.000945689814351
ko04924	Renin secretion	17/622	86/7206	0.00132077688034
ko05014	Amyotrophic lateral sclerosis (ALS)	15/622	74/7206	0.00138142752894
ko04260	Cardiac muscle contraction	18/622	98/7206	0.00173106033471
ko04660	T cell receptor signaling pathway	2/622	124/7206	0.00186428327274
ko04620	Toll-like receptor signaling pathway	1/622	100/7206	0.00197243949985
ko04110	Cell cycle	3/622	145/7206	0.00235363799882
ko00830	Retinol metabolism	10/622	42/7206	0.00247490386075
ko04668	TNF signaling pathway	2/622	120/7206	0.00270060352623
ko04022	cGMP-PKG signaling pathway	32/622	216/7206	0.00281921499059
ko05211	Renal cell carcinoma	1/622	96/7206	0.00290412092943
ko04658	Th1 and Th2 cell differentiation	1/622	96/7206	0.00290412092943
ko04931	Insulin resistance	3/622	137/7206	0.00317397286228
ko04070	Phosphatidylinositol signaling system	19/622	112/7206	0.00354937901928
ko04540	Gap junction	21/622	128/7206	0.00370197235314
ko04150	mTOR signaling pathway	6/622	184/7206	0.00502642483561
ko04657	IL-17 signaling pathway	1/622	87/7206	0.00625447808822
ko04371	Apelin signaling pathway	26/622	177/7206	0.00633600367253
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/622	182/7206	0.00690862948602
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/622	79/7206	0.00782698118681
ko05212	Pancreatic cancer	1/622	83/7206	0.00922251114734
ko04217	Necroptosis	6/622	178/7206	0.00943847386762
ko05200	Pathways in cancer	27/622	492/7206	0.00965857496213
ko05218	Melanoma	1/622	85/7206	0.00966703646619
ko05220	Chronic myeloid leukemia	1/622	85/7206	0.00966703646619
ko04510	Focal adhesion	10/622	240/7206	0.00969120432775
ko04062	Chemokine signaling pathway	28/622	201/7206	0.0103395912804
ko04350	TGF-beta signaling pathway	2/622	103/7206	0.0117162541963
ko04750	Inflammatory mediator regulation of TRP channels	19/622	122/7206	0.0131788427481
ko05130	Pathogenic Escherichia coli infection	1/622	77/7206	0.0132949616542
ko04810	Regulation of actin cytoskeleton	12/622	264/7206	0.013607851041
ko04072	Phospholipase D signaling pathway	27/622	197/7206	0.0141413330657
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/622	59/7206	0.0158094847128
ko04141	Protein processing in endoplasmic reticulum	7/622	184/7206	0.0158490955898
ko04630	Jak-STAT signaling pathway	4/622	132/7206	0.0177138889816
ko04918	Thyroid hormone synthesis	14/622	86/7206	0.0184754665122
ko04978	Mineral absorption	8/622	40/7206	0.0190367550962
ko04711	Circadian rhythm - fly	4/622	13/7206	0.0209132080035
ko04210	Apoptosis	7/622	180/7206	0.0211727225298
ko04014	Ras signaling pathway	35/622	279/7206	0.0220618712333
ko05414	Dilated cardiomyopathy	17/622	112/7206	0.0251957127027
ko04060	Cytokine-cytokine receptor interaction	8/622	191/7206	0.0254717182409
ko05217	Basal cell carcinoma	1/622	68/7206	0.0282484761643
ko05210	Colorectal cancer	2/622	86/7206	0.0320100133334
ko05133	Pertussis	2/622	87/7206	0.0323156860863
ko04662	B cell receptor signaling pathway	2/622	88/7206	0.0328102303667
ko05034	Alcoholism	30/622	238/7206	0.0337665975785
ko05202	Transcriptional misregulation in cancer	8/622	188/7206	0.0338025264634
ko04964	Proximal tubule bicarbonate reclamation	6/622	29/7206	0.0345003712084
ko00591	Linoleic acid metabolism	5/622	22/7206	0.0361345088891
ko00230	Purine metabolism	25/622	194/7206	0.0378061026286
ko04514	Cell adhesion molecules (CAMs)	18/622	130/7206	0.0396974061807
ko04270	Vascular smooth muscle contraction	21/622	154/7206	0.0403354035077
ko05213	Endometrial cancer	1/622	62/7206	0.0408831190377
ko04330	Notch signaling pathway	1/622	62/7206	0.0408831190377
ko05221	Acute myeloid leukemia	1/622	63/7206	0.0409363770024
ko04380	Osteoclast differentiation	5/622	134/7206	0.0420512304898
ko04145	Phagosome	7/622	162/7206	0.0470348997654