ko pathway ratio_in_study ratio_in_pop p_value ko05212 Pancreatic cancer 7/63 83/7206 6.84715769859e-06 ko01521 EGFR tyrosine kinase inhibitor resistance 7/63 106/7206 3.43444603836e-05 ko05215 Prostate cancer 7/63 111/7206 4.62567752083e-05 ko05160 Hepatitis C 8/63 153/7206 4.95095068501e-05 ko05219 Bladder cancer 5/63 48/7206 5.57467891904e-05 ko01522 Endocrine resistance 7/63 124/7206 9.38065932142e-05 ko05213 Endometrial cancer 5/63 62/7206 0.000191792611726 ko05221 Acute myeloid leukemia 5/63 63/7206 0.000206934890328 ko05223 Non-small cell lung cancer 5/63 66/7206 0.000257873936499 ko05200 Pathways in cancer 13/63 492/7206 0.000265272302031 ko04068 FoxO signaling pathway 7/63 167/7206 0.000587839001982 ko04668 TNF signaling pathway 6/63 120/7206 0.000589293114994 ko05224 Breast cancer 7/63 174/7206 0.000750899975857 ko04210 Apoptosis 7/63 180/7206 0.000917579482472 ko04662 B cell receptor signaling pathway 5/63 88/7206 0.000975648105093 ko04658 Th1 and Th2 cell differentiation 5/63 96/7206 0.00144302010761 ko04064 NF-kappa B signaling pathway 5/63 96/7206 0.00144302010761 ko04620 Toll-like receptor signaling pathway 5/63 100/7206 0.00173054504718 ko04012 ErbB signaling pathway 5/63 109/7206 0.00252886914934 ko05161 Hepatitis B 6/63 173/7206 0.0038436567811 ko05206 MicroRNAs in cancer 6/63 177/7206 0.00429967671323 ko04660 T cell receptor signaling pathway 5/63 124/7206 0.0044100334118 ko04664 Fc epsilon RI signaling pathway 4/63 77/7206 0.00445676235799 ko05214 Glioma 4/63 79/7206 0.00488441270342 ko05230 Central carbon metabolism in cancer 4/63 81/7206 0.0053388718864 ko05231 Choline metabolism in cancer 5/63 134/7206 0.00611840932445 ko05218 Melanoma 4/63 85/7206 0.00633115305992 ko05220 Chronic myeloid leukemia 4/63 85/7206 0.00633115305992 ko04931 Insulin resistance 5/63 137/7206 0.00671091491831 ko04072 Phospholipase D signaling pathway 6/63 197/7206 0.00720362200872 ko04015 Rap1 signaling pathway 7/63 278/7206 0.0102822390824 ko00590 Arachidonic acid metabolism 3/63 52/7206 0.0103804938162 ko04621 NOD-like receptor signaling pathway 5/63 157/7206 0.0117258364297 ko04070 Phosphatidylinositol signaling system 4/63 112/7206 0.0163116027823 ko04330 Notch signaling pathway 3/63 62/7206 0.0167036419557 ko04622 RIG-I-like receptor signaling pathway 3/63 62/7206 0.0167036419557 ko04910 Insulin signaling pathway 5/63 172/7206 0.0168502495325 ko00073 Cutin, suberine and wax biosynthesis 1/63 2/7206 0.0174101965691 ko04217 Necroptosis 5/63 178/7206 0.0192619620452 ko04151 PI3K-Akt signaling pathway 8/63 390/7206 0.0195064672399 ko04932 Non-alcoholic fatty liver disease (NAFLD) 5/63 182/7206 0.0209906008521 ko04750 Inflammatory mediator regulation of TRP channels 4/63 122/7206 0.0216305089545 ko04066 HIF-1 signaling pathway 4/63 123/7206 0.022214375441 ko04214 Apoptosis - fly 3/63 72/7206 0.0247735448483 ko05167 Kaposi's sarcoma-associated herpesvirus infection 5/63 191/7206 0.0252451267096 ko00261 Monobactam biosynthesis 1/63 3/7206 0.0260030835228 ko00512 Mucin type O-glycan biosynthesis 2/63 29/7206 0.026247123802 ko04915 Estrogen signaling pathway 4/63 131/7206 0.0272341700522 ko01523 Antifolate resistance 2/63 30/7206 0.027965828953 ko04380 Osteoclast differentiation 4/63 134/7206 0.0292785019762 ko04370 VEGF signaling pathway 3/63 77/7206 0.0294701503089 ko04320 Dorso-ventral axis formation 2/63 31/7206 0.0297286860554 ko05205 Proteoglycans in cancer 6/63 271/7206 0.0303095033503 ko04730 Long-term depression 3/63 78/7206 0.030462264992 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 3/63 79/7206 0.0314719170561 ko04610 Complement and coagulation cascades 3/63 79/7206 0.0314719170561 ko05169 Epstein-Barr virus infection 5/63 206/7206 0.0335048768125 ko04014 Ras signaling pathway 6/63 279/7206 0.0342617723948 ko04919 Thyroid hormone signaling pathway 4/63 143/7206 0.0359498526314 ko04920 Adipocytokine signaling pathway 3/63 89/7206 0.0425239496673 ko00562 Inositol phosphate metabolism 3/63 89/7206 0.0425239496673 ko05222 Small cell lung cancer 3/63 89/7206 0.0425239496673 ko05120 Epithelial cell signaling in Helicobacter pylori infection 3/63 92/7206 0.0461734848335 ko04623 Cytosolic DNA-sensing pathway 2/63 41/7206 0.0495982841965