ko pathway ratio_in_study ratio_in_pop p_value ko04621 NOD-like receptor signaling pathway 26/178 157/7206 5.6568446748e-15 ko04064 NF-kappa B signaling pathway 19/178 96/7206 1.19291617246e-12 ko04217 Necroptosis 22/178 178/7206 3.19756489278e-10 ko04620 Toll-like receptor signaling pathway 15/178 100/7206 1.75086165649e-08 ko04668 TNF signaling pathway 16/178 120/7206 3.24027170899e-08 ko05164 Influenza A 18/178 167/7206 1.24804165823e-07 ko04380 Osteoclast differentiation 16/178 134/7206 1.5698041655e-07 ko05168 Herpes simplex infection 17/178 182/7206 2.17972279392e-06 ko05152 Tuberculosis 17/178 187/7206 3.16899540394e-06 ko05167 Kaposi's sarcoma-associated herpesvirus infection 17/178 191/7206 4.23408107518e-06 ko05160 Hepatitis C 15/178 153/7206 4.89052439246e-06 ko05161 Hepatitis B 16/178 173/7206 5.01179417456e-06 ko05162 Measles 13/178 120/7206 7.19216046335e-06 ko04060 Cytokine-cytokine receptor interaction 16/178 191/7206 1.77545301312e-05 ko04622 RIG-I-like receptor signaling pathway 9/178 62/7206 1.83805961547e-05 ko04142 Lysosome 14/178 151/7206 1.94761425471e-05 ko04210 Apoptosis 15/178 180/7206 3.48932544257e-05 ko04623 Cytosolic DNA-sensing pathway 7/178 41/7206 5.512660409e-05 ko04660 T cell receptor signaling pathway 11/178 124/7206 0.000230059932185 ko05145 Toxoplasmosis 11/178 126/7206 0.000264826832313 ko04662 B cell receptor signaling pathway 9/178 88/7206 0.00029840008497 ko05321 Inflammatory bowel disease (IBD) 7/178 56/7206 0.000416314712169 ko05340 Primary immunodeficiency 5/178 30/7206 0.000750202728096 ko05140 Leishmaniasis 7/178 75/7206 0.00240505006551 ko05131 Shigellosis 7/178 82/7206 0.00398809472796 ko05142 Chagas disease (American trypanosomiasis) 9/178 130/7206 0.00474779916428 ko05144 Malaria 5/178 45/7206 0.00477262368165 ko05169 Epstein-Barr virus infection 12/178 206/7206 0.00487694569363 ko04630 Jak-STAT signaling pathway 9/178 132/7206 0.0052464197804 ko00512 Mucin type O-glycan biosynthesis 4/178 29/7206 0.00527468278494 ko04657 IL-17 signaling pathway 7/178 87/7206 0.0055310538361 ko04624 Toll and Imd signaling pathway 5/178 49/7206 0.00688230900796 ko05100 Bacterial invasion of epithelial cells 7/178 99/7206 0.0110194094456 ko04612 Antigen processing and presentation 6/178 77/7206 0.0116260776061 ko04672 Intestinal immune network for IgA production 4/178 37/7206 0.0125901449873 ko00531 Glycosaminoglycan degradation 3/178 23/7206 0.0182503229137 ko00600 Sphingolipid metabolism 5/178 63/7206 0.0192619620452 ko05221 Acute myeloid leukemia 5/178 63/7206 0.0192619620452 ko05215 Prostate cancer 7/178 111/7206 0.0196816291289 ko05330 Allograft rejection 3/178 24/7206 0.0204864357907 ko00511 Other glycan degradation 3/178 26/7206 0.0253902586855 ko05120 Epithelial cell signaling in Helicobacter pylori infection 6/178 92/7206 0.0258875256232 ko04215 Apoptosis - multiple species 4/178 47/7206 0.0281347045541 ko04658 Th1 and Th2 cell differentiation 6/178 96/7206 0.0310756183452 ko04214 Apoptosis - fly 5/178 72/7206 0.0321647201117 ko04650 Natural killer cell mediated cytotoxicity 6/178 97/7206 0.0324714265454 ko05320 Autoimmune thyroid disease 3/178 29/7206 0.0338216659654 ko05132 Salmonella infection 6/178 98/7206 0.033907487362 ko05146 Amoebiasis 6/178 99/7206 0.0353841375504 ko01523 Antifolate resistance 3/178 30/7206 0.0369162114461 ko00590 Arachidonic acid metabolism 4/178 52/7206 0.0388697656626 ko01524 Platinum drug resistance 5/178 76/7206 0.0392947952044 ko05418 Fluid shear stress and atherosclerosis 9/178 173/7206 0.0397489196607 ko05130 Pathogenic Escherichia coli infection 5/178 77/7206 0.0412162339266 ko04664 Fc epsilon RI signaling pathway 5/178 77/7206 0.0412162339266 ko05143 African trypanosomiasis 3/178 32/7206 0.0435244148313 ko04659 Th17 cell differentiation 6/178 106/7206 0.0468814565836 ko05203 Viral carcinogenesis 12/178 277/7206 0.0482625440876