ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	164/964	423/7206	4.71367082902e-42
ko04724	Glutamatergic synapse	81/964	152/7206	2.04949509212e-32
ko05033	Nicotine addiction	46/964	56/7206	2.35145564592e-31
ko05032	Morphine addiction	61/964	110/7206	7.18237906077e-26
ko04727	GABAergic synapse	59/964	110/7206	4.88117460256e-24
ko04728	Dopaminergic synapse	78/964	185/7206	9.94844454802e-23
ko04713	Circadian entrainment	64/964	136/7206	6.25474416967e-22
ko04723	Retrograde endocannabinoid signaling	72/964	175/7206	2.62430445206e-20
ko04725	Cholinergic synapse	68/964	160/7206	3.64646428005e-20
ko04721	Synaptic vesicle cycle	44/964	80/7206	8.79060699526e-19
ko04024	cAMP signaling pathway	88/964	279/7206	9.18048888046e-16
ko04911	Insulin secretion	49/964	117/7206	1.51982025992e-14
ko04726	Serotonergic synapse	52/964	137/7206	2.74007124388e-13
ko04742	Taste transduction	32/964	61/7206	3.10056162182e-13
ko04020	Calcium signaling pathway	80/964	265/7206	4.60043215907e-13
ko04261	Adrenergic signaling in cardiomyocytes	62/964	205/7206	1.94208294539e-10
ko05031	Amphetamine addiction	36/964	91/7206	3.47538405498e-10
ko04921	Oxytocin signaling pathway	62/964	209/7206	3.6124049102e-10
ko04720	Long-term potentiation	37/964	99/7206	1.31946427851e-09
ko04744	Phototransduction	20/964	36/7206	2.45223437816e-09
ko03040	Spliceosome	1/964	145/7206	3.76552761694e-08
ko04514	Cell adhesion molecules (CAMs)	40/964	130/7206	1.69195392142e-07
ko05030	Cocaine addiction	27/964	73/7206	2.91538998653e-07
ko04925	Aldosterone synthesis and secretion	34/964	105/7206	6.13585804164e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	26/964	74/7206	1.52127664055e-06
ko04971	Gastric acid secretion	31/964	98/7206	2.78253138099e-06
ko04360	Axon guidance	57/964	233/7206	3.17830527246e-06
ko05203	Viral carcinogenesis	14/964	277/7206	5.5218986522e-06
ko04972	Pancreatic secretion	33/964	111/7206	6.48691934954e-06
ko03013	RNA transport	5/964	166/7206	7.86133900227e-06
ko04970	Salivary secretion	29/964	95/7206	1.07895393979e-05
ko05168	Herpes simplex infection	7/964	182/7206	2.13971362444e-05
ko05164	Influenza A	6/964	167/7206	2.68862713287e-05
ko05322	Systemic lupus erythematosus	5/964	151/7206	4.87997178273e-05
ko04010	MAPK signaling pathway	69/964	321/7206	4.88661046336e-05
ko04070	Phosphatidylinositol signaling system	31/964	112/7206	5.77131009711e-05
ko04022	cGMP-PKG signaling pathway	50/964	216/7206	6.50764272639e-05
ko04621	NOD-like receptor signaling pathway	6/964	157/7206	7.6749238327e-05
ko04072	Phospholipase D signaling pathway	46/964	197/7206	0.000111121644418
ko04730	Long-term depression	23/964	78/7206	0.000156354509817
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/964	79/7206	0.000188466312535
ko04120	Ubiquitin mediated proteolysis	5/964	138/7206	0.000197909718853
ko04745	Phototransduction - fly	14/964	38/7206	0.000227740900272
ko04966	Collecting duct acid secretion	11/964	26/7206	0.000262532784323
ko04612	Antigen processing and presentation	1/964	77/7206	0.000308433382732
ko03008	Ribosome biogenesis in eukaryotes	1/964	79/7206	0.000325135017991
ko04060	Cytokine-cytokine receptor interaction	10/964	191/7206	0.000330142375329
ko04740	Olfactory transduction	23/964	80/7206	0.000347379056643
ko04260	Cardiac muscle contraction	26/964	98/7206	0.00045211992151
ko04141	Protein processing in endoplasmic reticulum	10/964	184/7206	0.000606034542529
ko04964	Proximal tubule bicarbonate reclamation	11/964	29/7206	0.000802521398236
ko04915	Estrogen signaling pathway	31/964	131/7206	0.00110064219969
ko04540	Gap junction	30/964	128/7206	0.00155371905848
ko04014	Ras signaling pathway	56/964	279/7206	0.00158571417273
ko05205	Proteoglycans in cancer	20/964	271/7206	0.00193910549751
ko04976	Bile secretion	21/964	80/7206	0.00235628035338
ko04640	Hematopoietic cell lineage	1/964	64/7206	0.00243325516811
ko04110	Cell cycle	8/964	145/7206	0.00291901125108
ko05140	Leishmaniasis	2/964	75/7206	0.00314396669078
ko04930	Type II diabetes mellitus	15/964	54/7206	0.00421485757317
ko04750	Inflammatory mediator regulation of TRP channels	28/964	122/7206	0.00433711935205
ko05161	Hepatitis B	11/964	173/7206	0.00442781058869
ko05414	Dilated cardiomyopathy	26/964	112/7206	0.00456721337852
ko04371	Apelin signaling pathway	37/964	177/7206	0.00489996409588
ko04064	NF-kappa B signaling pathway	4/964	96/7206	0.00581209422842
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/964	14/7206	0.00650852151724
ko00562	Inositol phosphate metabolism	21/964	89/7206	0.00731839264031
ko00240	Pyrimidine metabolism	6/964	110/7206	0.0105578658626
ko04146	Peroxisome	4/964	89/7206	0.0110895960046
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/964	59/7206	0.0112732865429
ko00330	Arginine and proline metabolism	2/964	61/7206	0.0135619984189
ko05162	Measles	7/964	120/7206	0.0139645517467
ko05169	Epstein-Barr virus infection	16/964	206/7206	0.0163662720134
ko03420	Nucleotide excision repair	1/964	46/7206	0.0166217358711
ko05219	Bladder cancer	1/964	48/7206	0.0169698118724
ko03320	PPAR signaling pathway	3/964	69/7206	0.0207043089985
ko05110	Vibrio cholerae infection	15/964	63/7206	0.0235081698336
ko03022	Basal transcription factors	1/964	44/7206	0.0245674524695
ko00071	Fatty acid degradation	1/964	45/7206	0.0251122022326
ko04626	Plant-pathogen interaction	6/964	18/7206	0.0251357868266
ko04217	Necroptosis	14/964	178/7206	0.0256978172132
ko00480	Glutathione metabolism	2/964	55/7206	0.0279312874725
ko04658	Th1 and Th2 cell differentiation	6/964	96/7206	0.0347151108252
ko04071	Sphingolipid signaling pathway	31/964	162/7206	0.0351586743541
ko00980	Metabolism of xenobiotics by cytochrome P450	1/964	40/7206	0.036114831919
ko00140	Steroid hormone biosynthesis	1/964	41/7206	0.036250622242
ko05410	Hypertrophic cardiomyopathy (HCM)	21/964	100/7206	0.036549743732
ko05133	Pertussis	5/964	87/7206	0.0377073973111
ko04710	Circadian rhythm	11/964	43/7206	0.0386265059846
ko04115	p53 signaling pathway	4/964	74/7206	0.0392950555007
ko00590	Arachidonic acid metabolism	2/964	52/7206	0.0399017933396
ko04923	Regulation of lipolysis in adipocytes	17/964	77/7206	0.0409404890492
ko00280	Valine, leucine and isoleucine degradation	2/964	54/7206	0.0414150558818