ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 36/299 191/7206 7.60255189945e-15 ko05340 Primary immunodeficiency 15/299 30/7206 1.16378248386e-13 ko04621 NOD-like receptor signaling pathway 30/299 157/7206 1.06778499583e-12 ko05164 Influenza A 30/299 167/7206 5.65993135411e-12 ko04650 Natural killer cell mediated cytotoxicity 22/299 97/7206 3.77391285603e-11 ko05162 Measles 24/299 120/7206 8.05679660497e-11 ko05152 Tuberculosis 30/299 187/7206 1.09100852883e-10 ko05140 Leishmaniasis 19/299 75/7206 1.09119860202e-10 ko04064 NF-kappa B signaling pathway 21/299 96/7206 2.20522374715e-10 ko05145 Toxoplasmosis 24/299 126/7206 2.35050698503e-10 ko05168 Herpes simplex infection 28/299 182/7206 1.27802559855e-09 ko04380 Osteoclast differentiation 23/299 134/7206 4.76304529039e-09 ko04612 Antigen processing and presentation 17/299 77/7206 1.04577864661e-08 ko05150 Staphylococcus aureus infection 12/299 36/7206 1.07026559464e-08 ko04217 Necroptosis 26/299 178/7206 1.57089561968e-08 ko04620 Toll-like receptor signaling pathway 19/299 100/7206 1.95817929934e-08 ko05321 Inflammatory bowel disease (IBD) 14/299 56/7206 3.9817455673e-08 ko04659 Th17 cell differentiation 19/299 106/7206 5.27354388546e-08 ko05330 Allograft rejection 9/299 24/7206 2.440234291e-07 ko05167 Kaposi's sarcoma-associated herpesvirus infection 25/299 191/7206 2.69979239084e-07 ko05320 Autoimmune thyroid disease 9/299 29/7206 1.55527794312e-06 ko04658 Th1 and Th2 cell differentiation 16/299 96/7206 1.69044012967e-06 ko05133 Pertussis 15/299 87/7206 2.30757163114e-06 ko05161 Hepatitis B 22/299 173/7206 2.36136042696e-06 ko04660 T cell receptor signaling pathway 18/299 124/7206 3.02183793569e-06 ko05332 Graft-versus-host disease 7/299 18/7206 4.23563603013e-06 ko04622 RIG-I-like receptor signaling pathway 12/299 62/7206 6.99438096793e-06 ko04630 Jak-STAT signaling pathway 18/299 132/7206 7.47681227682e-06 ko04062 Chemokine signaling pathway 23/299 201/7206 8.52222426946e-06 ko05144 Malaria 10/299 45/7206 1.14009755493e-05 ko04610 Complement and coagulation cascades 13/299 79/7206 1.86165332306e-05 ko04623 Cytosolic DNA-sensing pathway 9/299 41/7206 3.50403651721e-05 ko04145 Phagosome 19/299 162/7206 3.73417754936e-05 ko05310 Asthma 6/299 17/7206 4.07731019054e-05 ko04640 Hematopoietic cell lineage 11/299 64/7206 5.43112521293e-05 ko05142 Chagas disease (American trypanosomiasis) 16/299 130/7206 8.63372141208e-05 ko04672 Intestinal immune network for IgA production 8/299 37/7206 0.000107812914952 ko04662 B cell receptor signaling pathway 12/299 88/7206 0.000252905551379 ko04940 Type I diabetes mellitus 7/299 32/7206 0.000271328769833 ko05323 Rheumatoid arthritis 12/299 89/7206 0.000281678770258 ko03050 Proteasome 9/299 54/7206 0.000330906067842 ko05160 Hepatitis C 16/299 153/7206 0.000573504060394 ko05034 Alcoholism 1/299 238/7206 0.000743478897912 ko04360 Axon guidance 1/299 233/7206 0.00113748978636 ko00590 Arachidonic acid metabolism 8/299 52/7206 0.00122351099051 ko04668 TNF signaling pathway 13/299 120/7206 0.00134264359149 ko05416 Viral myocarditis 8/299 55/7206 0.00177745154944 ko04137 Mitophagy - animal 10/299 82/7206 0.0019663686908 ko04514 Cell adhesion molecules (CAMs) 13/299 130/7206 0.00276886523735 ko04210 Apoptosis 16/299 180/7206 0.00363142688691 ko04664 Fc epsilon RI signaling pathway 9/299 77/7206 0.00436117816736 ko04666 Fc gamma R-mediated phagocytosis 12/299 122/7206 0.00455400719388 ko05169 Epstein-Barr virus infection 17/299 206/7206 0.00660214029524 ko05131 Shigellosis 9/299 82/7206 0.00661667616352 ko04310 Wnt signaling pathway 1/299 181/7206 0.00719024943373 ko04728 Dopaminergic synapse 1/299 185/7206 0.00745696367064 ko00120 Primary bile acid biosynthesis 4/299 20/7206 0.00831151886642 ko05143 African trypanosomiasis 5/299 32/7206 0.00953060501538 ko04080 Neuroactive ligand-receptor interaction 8/299 423/7206 0.0118116563424 ko04550 Signaling pathways regulating pluripotency of stem cells 1/299 165/7206 0.0154899696867 ko05166 HTLV-I infection 20/299 292/7206 0.0240316994285 ko04390 Hippo signaling pathway 2/299 188/7206 0.0249531228806 ko00480 Glutathione metabolism 6/299 55/7206 0.0255224398655 ko04020 Calcium signaling pathway 4/299 265/7206 0.0263430318408 ko04114 Oocyte meiosis 1/299 139/7206 0.0311588454101 ko00966 Glucosinolate biosynthesis 1/299 1/7206 0.0414932001111 ko04611 Platelet activation 12/299 163/7206 0.0456796196216 ko04910 Insulin signaling pathway 2/299 172/7206 0.0496862159026