ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	206/1300	423/7206	1.91672740251e-50
ko04724	Glutamatergic synapse	92/1300	152/7206	4.88635326712e-32
ko04713	Circadian entrainment	79/1300	136/7206	6.03567586856e-26
ko04727	GABAergic synapse	69/1300	110/7206	1.39125966694e-25
ko05033	Nicotine addiction	46/1300	56/7206	1.71731371035e-25
ko05032	Morphine addiction	68/1300	110/7206	1.0941961247e-24
ko04721	Synaptic vesicle cycle	53/1300	80/7206	1.52115893577e-21
ko04020	Calcium signaling pathway	110/1300	265/7206	9.35422382026e-20
ko04725	Cholinergic synapse	78/1300	160/7206	2.84461130087e-19
ko04728	Dopaminergic synapse	85/1300	185/7206	8.04947020278e-19
ko04723	Retrograde endocannabinoid signaling	79/1300	175/7206	5.18182945788e-17
ko04024	cAMP signaling pathway	107/1300	279/7206	2.85401661499e-16
ko04921	Oxytocin signaling pathway	86/1300	209/7206	2.58248386719e-15
ko04911	Insulin secretion	58/1300	117/7206	4.75820424468e-15
ko04726	Serotonergic synapse	64/1300	137/7206	6.95177841857e-15
ko04742	Taste transduction	38/1300	61/7206	1.72859270759e-14
ko04744	Phototransduction	27/1300	36/7206	1.15642317192e-13
ko04970	Salivary secretion	47/1300	95/7206	2.13204455122e-12
ko04720	Long-term potentiation	46/1300	99/7206	5.8520749021e-11
ko04261	Adrenergic signaling in cardiomyocytes	76/1300	205/7206	6.2013470536e-11
ko05031	Amphetamine addiction	43/1300	91/7206	1.2623096738e-10
ko03040	Spliceosome	2/1300	145/7206	2.22624090754e-10
ko04022	cGMP-PKG signaling pathway	77/1300	216/7206	3.99918129852e-10
ko04740	Olfactory transduction	38/1300	80/7206	1.25993226188e-09
ko05168	Herpes simplex infection	7/1300	182/7206	7.47527459413e-09
ko04060	Cytokine-cytokine receptor interaction	9/1300	191/7206	5.172696116e-08
ko05203	Viral carcinogenesis	19/1300	277/7206	6.64390931044e-08
ko03013	RNA transport	7/1300	166/7206	1.0938963814e-07
ko04925	Aldosterone synthesis and secretion	42/1300	105/7206	1.09866293787e-07
ko04540	Gap junction	48/1300	128/7206	1.51446973217e-07
ko05322	Systemic lupus erythematosus	6/1300	151/7206	2.77295578414e-07
ko04971	Gastric acid secretion	39/1300	98/7206	3.78627261488e-07
ko04360	Axon guidance	73/1300	233/7206	5.72617106943e-07
ko04730	Long-term depression	32/1300	78/7206	1.7847377568e-06
ko04924	Renin secretion	34/1300	86/7206	2.78594118549e-06
ko04120	Ubiquitin mediated proteolysis	6/1300	138/7206	2.83426046405e-06
ko04110	Cell cycle	7/1300	145/7206	3.15509043298e-06
ko04260	Cardiac muscle contraction	37/1300	98/7206	3.58110707235e-06
ko05030	Cocaine addiction	30/1300	73/7206	3.72661395396e-06
ko04966	Collecting duct acid secretion	15/1300	26/7206	6.76584746274e-06
ko04972	Pancreatic secretion	39/1300	111/7206	1.53242349906e-05
ko05164	Influenza A	11/1300	167/7206	2.39395095695e-05
ko04371	Apelin signaling pathway	55/1300	177/7206	2.52478549905e-05
ko04745	Phototransduction - fly	18/1300	38/7206	3.14246583845e-05
ko03008	Ribosome biogenesis in eukaryotes	2/1300	79/7206	4.46027914921e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	28/1300	74/7206	4.94149056207e-05
ko04070	Phosphatidylinositol signaling system	38/1300	112/7206	5.29232747124e-05
ko04626	Plant-pathogen interaction	11/1300	18/7206	5.79916078477e-05
ko04141	Protein processing in endoplasmic reticulum	14/1300	184/7206	6.0184180696e-05
ko04750	Inflammatory mediator regulation of TRP channels	40/1300	122/7206	7.0980828473e-05
ko04514	Cell adhesion molecules (CAMs)	42/1300	130/7206	7.22173741815e-05
ko04010	MAPK signaling pathway	86/1300	321/7206	7.51996484132e-05
ko04064	NF-kappa B signaling pathway	4/1300	96/7206	7.88966501507e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	29/1300	79/7206	8.37412750674e-05
ko05169	Epstein-Barr virus infection	17/1300	206/7206	9.68894966778e-05
ko04976	Bile secretion	29/1300	80/7206	9.82376756281e-05
ko05140	Leishmaniasis	2/1300	75/7206	0.000104135639025
ko05414	Dilated cardiomyopathy	37/1300	112/7206	0.000104246676891
ko04214	Apoptosis - fly	2/1300	72/7206	0.000150161308747
ko04014	Ras signaling pathway	75/1300	279/7206	0.000178572979624
ko04964	Proximal tubule bicarbonate reclamation	14/1300	29/7206	0.000186418907249
ko04610	Complement and coagulation cascades	3/1300	79/7206	0.000305114278288
ko04072	Phospholipase D signaling pathway	56/1300	197/7206	0.000316805191117
ko05110	Vibrio cholerae infection	23/1300	63/7206	0.000426020720412
ko05162	Measles	8/1300	120/7206	0.000454142922093
ko04621	NOD-like receptor signaling pathway	13/1300	157/7206	0.000713656225484
ko04330	Notch signaling pathway	2/1300	62/7206	0.00073526585675
ko04915	Estrogen signaling pathway	39/1300	131/7206	0.000830352062656
ko05205	Proteoglycans in cancer	29/1300	271/7206	0.000917440327501
ko04961	Endocrine and other factor-regulated calcium reabsorption	21/1300	59/7206	0.00108408660706
ko04612	Antigen processing and presentation	4/1300	77/7206	0.00152711748091
ko03420	Nucleotide excision repair	1/1300	46/7206	0.00176465398423
ko05161	Hepatitis B	16/1300	173/7206	0.00177327029233
ko00520	Amino sugar and nucleotide sugar metabolism	2/1300	55/7206	0.00240246698806
ko00480	Glutathione metabolism	2/1300	55/7206	0.00240246698806
ko04923	Regulation of lipolysis in adipocytes	25/1300	77/7206	0.00243145608028
ko05321	Inflammatory bowel disease (IBD)	2/1300	56/7206	0.00245663990605
ko03022	Basal transcription factors	1/1300	44/7206	0.00267294398323
ko00071	Fatty acid degradation	1/1300	45/7206	0.00275082392678
ko04146	Peroxisome	6/1300	89/7206	0.00328842672647
ko04668	TNF signaling pathway	10/1300	120/7206	0.00380056739903
ko04622	RIG-I-like receptor signaling pathway	3/1300	62/7206	0.0041759021388
ko04657	IL-17 signaling pathway	6/1300	87/7206	0.00459162934282
ko05145	Toxoplasmosis	11/1300	126/7206	0.00472517022917
ko04922	Glucagon signaling pathway	36/1300	128/7206	0.00500043818875
ko00240	Pyrimidine metabolism	9/1300	110/7206	0.00553717859918
ko04630	Jak-STAT signaling pathway	12/1300	132/7206	0.00576301074429
ko03018	RNA degradation	6/1300	84/7206	0.00631818499865
ko01524	Platinum drug resistance	5/1300	76/7206	0.00642659346948
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/1300	14/7206	0.00643948502829
ko04930	Type II diabetes mellitus	18/1300	54/7206	0.006686538501
ko04210	Apoptosis	19/1300	180/7206	0.00771397367289
ko05410	Hypertrophic cardiomyopathy (HCM)	29/1300	100/7206	0.00815307133026
ko04710	Circadian rhythm	15/1300	43/7206	0.00818580406439
ko05166	HTLV-I infection	36/1300	292/7206	0.00819023222195
ko00562	Inositol phosphate metabolism	26/1300	89/7206	0.00825695118591
ko05131	Shigellosis	6/1300	82/7206	0.00874444880387
ko00310	Lysine degradation	5/1300	73/7206	0.00894135321982
ko04658	Th1 and Th2 cell differentiation	8/1300	96/7206	0.0106203389057
ko05133	Pertussis	7/1300	87/7206	0.0113360900177
ko04912	GnRH signaling pathway	33/1300	122/7206	0.0123019826682
ko04270	Vascular smooth muscle contraction	40/1300	154/7206	0.0143023475363
ko04916	Melanogenesis	37/1300	142/7206	0.0151441494184
ko04620	Toll-like receptor signaling pathway	9/1300	100/7206	0.0175914021498
ko00590	Arachidonic acid metabolism	3/1300	52/7206	0.0175962459759
ko05212	Pancreatic cancer	7/1300	83/7206	0.0207881538919
ko04115	p53 signaling pathway	6/1300	74/7206	0.0222983621066
ko04213	Longevity regulating pathway - multiple species	24/1300	86/7206	0.0230639379234
ko05222	Small cell lung cancer	8/1300	89/7206	0.0255304923323
ko04350	TGF-beta signaling pathway	10/1300	103/7206	0.0273878062718
ko05231	Choline metabolism in cancer	34/1300	134/7206	0.030844897042
ko04142	Lysosome	17/1300	151/7206	0.0316832009258
ko00010	Glycolysis / Gluconeogenesis	21/1300	74/7206	0.0317053900418
ko00600	Sphingolipid metabolism	5/1300	63/7206	0.0325345867116
ko04640	Hematopoietic cell lineage	5/1300	64/7206	0.0326290507237
ko00630	Glyoxylate and dicarboxylate metabolism	2/1300	38/7206	0.0349410505553
ko03410	Base excision repair	2/1300	38/7206	0.0349410505553
ko05219	Bladder cancer	3/1300	48/7206	0.0360410219713
ko00980	Metabolism of xenobiotics by cytochrome P450	2/1300	40/7206	0.0361176315923
ko04960	Aldosterone-regulated sodium reabsorption	13/1300	41/7206	0.0382655799849
ko04113	Meiosis - yeast	6/1300	70/7206	0.0410158842367
ko05418	Fluid shear stress and atherosclerosis	21/1300	173/7206	0.0447293758463
ko05200	Pathways in cancer	72/1300	492/7206	0.0448350697468
ko04015	Rap1 signaling pathway	63/1300	278/7206	0.0464648342055
ko00280	Valine, leucine and isoleucine degradation	4/1300	54/7206	0.0484386742779