ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	98/541	423/7206	8.50904963753e-26
ko05033	Nicotine addiction	28/541	56/7206	1.74497324511e-17
ko04724	Glutamatergic synapse	42/541	152/7206	3.15713542102e-14
ko04727	GABAergic synapse	35/541	110/7206	4.58341944118e-14
ko05032	Morphine addiction	35/541	110/7206	4.58341944118e-14
ko04744	Phototransduction	19/541	36/7206	8.18072577951e-13
ko04024	cAMP signaling pathway	55/541	279/7206	1.34292125884e-11
ko04713	Circadian entrainment	35/541	136/7206	4.33115103689e-11
ko04723	Retrograde endocannabinoid signaling	39/541	175/7206	3.59894174276e-10
ko04728	Dopaminergic synapse	40/541	185/7206	5.57884107583e-10
ko04726	Serotonergic synapse	33/541	137/7206	1.02943327988e-09
ko04976	Bile secretion	24/541	80/7206	1.87245220937e-09
ko04725	Cholinergic synapse	35/541	160/7206	5.01332924282e-09
ko04972	Pancreatic secretion	28/541	111/7206	6.50611434467e-09
ko04974	Protein digestion and absorption	25/541	96/7206	2.13277647261e-08
ko04742	Taste transduction	19/541	61/7206	4.74949775055e-08
ko04740	Olfactory transduction	20/541	80/7206	1.13406599303e-06
ko04911	Insulin secretion	24/541	117/7206	4.52814226095e-06
ko05030	Cocaine addiction	18/541	73/7206	4.82377766323e-06
ko04970	Salivary secretion	20/541	95/7206	1.88858538861e-05
ko04978	Mineral absorption	12/541	40/7206	2.25516118144e-05
ko04964	Proximal tubule bicarbonate reclamation	10/541	29/7206	2.83681726323e-05
ko03013	RNA transport	1/541	166/7206	6.68645110072e-05
ko04721	Synaptic vesicle cycle	17/541	80/7206	7.00023460553e-05
ko04971	Gastric acid secretion	19/541	98/7206	9.99966249508e-05
ko05031	Amphetamine addiction	18/541	91/7206	0.00011585986839
ko05169	Epstein-Barr virus infection	3/541	206/7206	0.000138656721511
ko05203	Viral carcinogenesis	6/541	277/7206	0.00015986663077
ko05166	HTLV-I infection	7/541	292/7206	0.000236810638692
ko03040	Spliceosome	1/541	145/7206	0.000318797770541
ko04110	Cell cycle	1/541	145/7206	0.000318797770541
ko05014	Amyotrophic lateral sclerosis (ALS)	15/541	74/7206	0.000320718595893
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/541	59/7206	0.000338786997223
ko04390	Hippo signaling pathway	3/541	188/7206	0.000603958370102
ko04621	NOD-like receptor signaling pathway	2/541	157/7206	0.000653966912697
ko04217	Necroptosis	3/541	178/7206	0.000826179861647
ko00830	Retinol metabolism	10/541	42/7206	0.00085609252473
ko05162	Measles	1/541	120/7206	0.00141440810059
ko05016	Huntington's disease	5/541	215/7206	0.00145043115976
ko05164	Influenza A	3/541	167/7206	0.00166263881701
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/541	182/7206	0.00261330650256
ko04141	Protein processing in endoplasmic reticulum	4/541	184/7206	0.00261941089341
ko04120	Ubiquitin mediated proteolysis	2/541	138/7206	0.00283258771876
ko04921	Oxytocin signaling pathway	28/541	209/7206	0.00295732453002
ko04973	Carbohydrate digestion and absorption	9/541	42/7206	0.00336064070749
ko04218	Cellular senescence	4/541	177/7206	0.00362998240475
ko04975	Fat digestion and absorption	8/541	35/7206	0.00367789741105
ko04020	Calcium signaling pathway	33/541	265/7206	0.00398380662175
ko05322	Systemic lupus erythematosus	3/541	151/7206	0.00465709463533
ko05161	Hepatitis B	4/541	173/7206	0.00505425826636
ko00190	Oxidative phosphorylation	2/541	127/7206	0.00578433964664
ko04261	Adrenergic signaling in cardiomyocytes	26/541	205/7206	0.00695385886289
ko05152	Tuberculosis	5/541	187/7206	0.00711089052322
ko04925	Aldosterone synthesis and secretion	16/541	105/7206	0.00736777618776
ko02010	ABC transporters	8/541	39/7206	0.00737612022898
ko04614	Renin-angiotensin system	5/541	18/7206	0.00882261575951
ko04310	Wnt signaling pathway	5/541	181/7206	0.00967338358838
ko05168	Herpes simplex infection	5/541	182/7206	0.00970725234277
ko04150	mTOR signaling pathway	5/541	184/7206	0.00987458903993
ko04550	Signaling pathways regulating pluripotency of stem cells	4/541	165/7206	0.00998655382124
ko04960	Aldosterone-regulated sodium reabsorption	8/541	41/7206	0.0100385408207
ko00983	Drug metabolism - other enzymes	8/541	42/7206	0.0116098114355
ko04924	Renin secretion	13/541	86/7206	0.0124779772515
ko04933	AGE-RAGE signaling pathway in diabetic complications	3/541	135/7206	0.0127497698816
ko04111	Cell cycle - yeast	1/541	90/7206	0.0139499190573
ko04730	Long-term depression	12/541	78/7206	0.0150064186366
ko05215	Prostate cancer	2/541	111/7206	0.0166791853899
ko05034	Alcoholism	28/541	238/7206	0.0166916215903
ko04540	Gap junction	17/541	128/7206	0.0175187231937
ko04137	Mitophagy - animal	1/541	82/7206	0.0200117075458
ko03018	RNA degradation	1/541	84/7206	0.0201301250493
ko05220	Chronic myeloid leukemia	1/541	85/7206	0.0203695377039
ko04745	Phototransduction - fly	7/541	38/7206	0.0211933188296
ko04350	TGF-beta signaling pathway	2/541	103/7206	0.0232624112972
ko04140	Autophagy - animal	5/541	164/7206	0.0238920275286
ko05145	Toxoplasmosis	3/541	126/7206	0.0248689652568
ko04144	Endocytosis	15/541	342/7206	0.0264603695118
ko05130	Pathogenic Escherichia coli infection	1/541	77/7206	0.0289966368092
ko04612	Antigen processing and presentation	1/541	77/7206	0.0289966368092
ko00140	Steroid hormone biosynthesis	7/541	41/7206	0.0311212261307
ko04931	Insulin resistance	4/541	137/7206	0.0334142492026
ko00350	Tyrosine metabolism	6/541	33/7206	0.0338599855314
ko04918	Thyroid hormone synthesis	12/541	86/7206	0.0356382395198
ko04060	Cytokine-cytokine receptor interaction	7/541	191/7206	0.0367945112866
ko04214	Apoptosis - fly	1/541	72/7206	0.0419730008644
ko04630	Jak-STAT signaling pathway	4/541	132/7206	0.0451459858711
ko03015	mRNA surveillance pathway	2/541	93/7206	0.0461303321619
ko04658	Th1 and Th2 cell differentiation	2/541	96/7206	0.0475636069794
ko00910	Nitrogen metabolism	4/541	19/7206	0.0493232131351
ko04260	Cardiac muscle contraction	13/541	98/7206	0.0494610299147