ko pathway ratio_in_study ratio_in_pop p_value ko05033 Nicotine addiction 4/45 56/7206 0.000384680937153 ko04723 Retrograde endocannabinoid signaling 6/45 175/7206 0.000698527202703 ko04080 Neuroactive ligand-receptor interaction 9/45 423/7206 0.0010148362552 ko04970 Salivary secretion 4/45 95/7206 0.00279355076351 ko04727 GABAergic synapse 4/45 110/7206 0.00473352047077 ko05032 Morphine addiction 4/45 110/7206 0.00473352047077 ko04728 Dopaminergic synapse 5/45 185/7206 0.00561599164537 ko04024 cAMP signaling pathway 6/45 279/7206 0.0072957558453 ko05030 Cocaine addiction 3/45 73/7206 0.0104384985785 ko04721 Synaptic vesicle cycle 3/45 80/7206 0.013378411921 ko04724 Glutamatergic synapse 4/45 152/7206 0.014500352132 ko00760 Nicotinate and nicotinamide metabolism 2/45 34/7206 0.0188466243161 ko00680 Methane metabolism 2/45 34/7206 0.0188466243161 ko04972 Pancreatic secretion 3/45 111/7206 0.0316101847569 ko04911 Insulin secretion 3/45 117/7206 0.0361298562783 ko04514 Cell adhesion molecules (CAMs) 3/45 130/7206 0.0470047428971 ko04010 MAPK signaling pathway 5/45 321/7206 0.0483963545591