ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	91/652	145/7206	8.53249400865e-60
ko04110	Cell cycle	62/652	145/7206	7.25380456882e-28
ko03013	RNA transport	62/652	166/7206	5.14073183543e-24
ko04111	Cell cycle - yeast	45/652	90/7206	5.63332584872e-24
ko03030	DNA replication	28/652	38/7206	6.99427568376e-22
ko04113	Meiosis - yeast	32/652	70/7206	6.27795747429e-16
ko03015	mRNA surveillance pathway	35/652	93/7206	3.84930305625e-14
ko03430	Mismatch repair	16/652	22/7206	7.54990982066e-13
ko03420	Nucleotide excision repair	22/652	46/7206	7.70919260204e-12
ko03410	Base excision repair	19/652	38/7206	7.90439442033e-11
ko03018	RNA degradation	28/652	84/7206	4.00366816629e-10
ko03022	Basal transcription factors	19/652	44/7206	1.8677068839e-09
ko00240	Pyrimidine metabolism	31/652	110/7206	4.92761128842e-09
ko04020	Calcium signaling pathway	2/652	265/7206	5.22265463074e-09
ko03440	Homologous recombination	16/652	41/7206	2.01094158126e-07
ko04144	Endocytosis	8/652	342/7206	5.52413389132e-07
ko04723	Retrograde endocannabinoid signaling	1/652	175/7206	1.58277219083e-06
ko04024	cAMP signaling pathway	6/652	279/7206	3.28570748658e-06
ko05168	Herpes simplex infection	36/652	182/7206	5.19134762016e-06
ko04120	Ubiquitin mediated proteolysis	30/652	138/7206	5.89092184636e-06
ko03460	Fanconi anemia pathway	16/652	51/7206	5.90530167156e-06
ko05010	Alzheimer's disease	3/652	202/7206	9.58963108521e-06
ko04724	Glutamatergic synapse	1/652	152/7206	1.17442332406e-05
ko04114	Oocyte meiosis	29/652	139/7206	1.53785618437e-05
ko03008	Ribosome biogenesis in eukaryotes	20/652	79/7206	1.60103403652e-05
ko04921	Oxytocin signaling pathway	4/652	209/7206	3.88395468786e-05
ko05169	Epstein-Barr virus infection	37/652	206/7206	5.77861151228e-05
ko04726	Serotonergic synapse	1/652	137/7206	5.85654643398e-05
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/652	182/7206	6.20836520875e-05
ko04725	Cholinergic synapse	2/652	160/7206	6.49663299091e-05
ko04915	Estrogen signaling pathway	1/652	131/7206	8.50944961664e-05
ko04371	Apelin signaling pathway	3/652	177/7206	8.89063177128e-05
ko05012	Parkinson's disease	2/652	155/7206	9.39018736958e-05
ko04621	NOD-like receptor signaling pathway	2/652	157/7206	9.90322418451e-05
ko03010	Ribosome	1/652	129/7206	0.000131690833051
ko04514	Cell adhesion molecules (CAMs)	1/652	130/7206	0.000136765579265
ko04911	Insulin secretion	1/652	117/7206	0.000276980225116
ko04072	Phospholipase D signaling pathway	5/652	197/7206	0.000360287469321
ko04022	cGMP-PKG signaling pathway	6/652	216/7206	0.000399281986464
ko04713	Circadian entrainment	2/652	136/7206	0.000416819551138
ko04810	Regulation of actin cytoskeleton	9/652	264/7206	0.000421868614521
ko04270	Vascular smooth muscle contraction	3/652	154/7206	0.00053946714227
ko04015	Rap1 signaling pathway	10/652	278/7206	0.00056948641136
ko04727	GABAergic synapse	1/652	110/7206	0.00061023508696
ko05032	Morphine addiction	1/652	110/7206	0.00061023508696
ko05231	Choline metabolism in cancer	2/652	134/7206	0.000629590617489
ko05414	Dilated cardiomyopathy	1/652	112/7206	0.000643111833052
ko05152	Tuberculosis	5/652	187/7206	0.00070323974678
ko04261	Adrenergic signaling in cardiomyocytes	6/652	205/7206	0.000750933082699
ko05166	HTLV-I infection	44/652	292/7206	0.000763032274772
ko05145	Toxoplasmosis	2/652	126/7206	0.00087544280396
ko04611	Platelet activation	4/652	163/7206	0.00127125733212
ko05410	Hypertrophic cardiomyopathy (HCM)	1/652	100/7206	0.0013140979963
ko04712	Circadian rhythm - plant	4/652	7/7206	0.00186049368047
ko04010	MAPK signaling pathway	14/652	321/7206	0.0018772010091
ko04974	Protein digestion and absorption	1/652	96/7206	0.00193827130972
ko04151	PI3K-Akt signaling pathway	19/652	390/7206	0.00195555734552
ko00230	Purine metabolism	31/652	194/7206	0.00203692039427
ko04910	Insulin signaling pathway	5/652	172/7206	0.00269652830339
ko04014	Ras signaling pathway	12/652	279/7206	0.00280303943168
ko04380	Osteoclast differentiation	3/652	134/7206	0.00328554345571
ko03020	RNA polymerase	8/652	29/7206	0.00331618857384
ko04062	Chemokine signaling pathway	7/652	201/7206	0.00372648432367
ko04213	Longevity regulating pathway - multiple species	1/652	86/7206	0.0041800692456
ko04924	Renin secretion	1/652	86/7206	0.0041800692456
ko04662	B cell receptor signaling pathway	1/652	88/7206	0.00422597700543
ko04540	Gap junction	3/652	128/7206	0.00449028202545
ko04217	Necroptosis	6/652	178/7206	0.00500809941372
ko04925	Aldosterone synthesis and secretion	2/652	105/7206	0.00543634177927
ko04912	GnRH signaling pathway	3/652	122/7206	0.00621378168502
ko04066	HIF-1 signaling pathway	3/652	123/7206	0.00627871154496
ko04660	T cell receptor signaling pathway	3/652	124/7206	0.00638670395758
ko05146	Amoebiasis	2/652	99/7206	0.00774397118619
ko04620	Toll-like receptor signaling pathway	2/652	100/7206	0.00775255346379
ko04730	Long-term depression	1/652	78/7206	0.00897336987915
ko04976	Bile secretion	1/652	80/7206	0.00923040734182
ko04142	Lysosome	5/652	151/7206	0.00926501212475
ko05160	Hepatitis C	5/652	153/7206	0.00947045761678
ko04931	Insulin resistance	4/652	137/7206	0.00953084589758
ko05203	Viral carcinogenesis	38/652	277/7206	0.00985550304543
ko04658	Th1 and Th2 cell differentiation	2/652	96/7206	0.0111063352176
ko04071	Sphingolipid signaling pathway	6/652	162/7206	0.0122232179447
ko01200	Carbon metabolism	4/652	128/7206	0.0126014841451
ko04922	Glucagon signaling pathway	4/652	128/7206	0.0126014841451
ko05030	Cocaine addiction	1/652	73/7206	0.0131015708398
ko03060	Protein export	6/652	23/7206	0.014195217148
ko04914	Progesterone-mediated oocyte maturation	17/652	104/7206	0.0147135614869
ko04728	Dopaminergic synapse	8/652	185/7206	0.0191314253863
ko04360	Axon guidance	11/652	233/7206	0.0194092436823
ko04510	Focal adhesion	12/652	240/7206	0.0220785707871
ko04918	Thyroid hormone synthesis	2/652	86/7206	0.0223187047913
ko04917	Prolactin signaling pathway	2/652	87/7206	0.0224564953807
ko04933	AGE-RAGE signaling pathway in diabetic complications	5/652	135/7206	0.0230151251289
ko04146	Peroxisome	2/652	89/7206	0.0231968933445
ko04920	Adipocytokine signaling pathway	2/652	89/7206	0.0231968933445
ko04218	Cellular senescence	25/652	177/7206	0.0232925546889
ko04668	TNF signaling pathway	4/652	120/7206	0.0237065975909
ko04750	Inflammatory mediator regulation of TRP channels	4/652	122/7206	0.0241652792894
ko04659	Th17 cell differentiation	3/652	106/7206	0.0244540071056
ko04330	Notch signaling pathway	11/652	62/7206	0.0245649278093
ko03050	Proteasome	10/652	54/7206	0.0271527996629
ko04630	Jak-STAT signaling pathway	5/652	132/7206	0.0310167768551
ko05230	Central carbon metabolism in cancer	2/652	81/7206	0.0315545962037
ko04720	Long-term potentiation	3/652	99/7206	0.0327952734408
ko00564	Glycerophospholipid metabolism	3/652	99/7206	0.0327952734408
ko04115	p53 signaling pathway	12/652	74/7206	0.0398935472935
ko03450	Non-homologous end-joining	4/652	15/7206	0.0404493813581
ko04961	Endocrine and other factor-regulated calcium reabsorption	1/652	59/7206	0.0404921897159
ko01212	Fatty acid metabolism	1/652	60/7206	0.04050368468
ko04622	RIG-I-like receptor signaling pathway	1/652	62/7206	0.0415138926718
ko04913	Ovarian steroidogenesis	1/652	63/7206	0.0425099179669
ko00561	Glycerolipid metabolism	1/652	63/7206	0.0425099179669
ko05142	Chagas disease (American trypanosomiasis)	5/652	130/7206	0.042682254326
ko04012	ErbB signaling pathway	4/652	109/7206	0.0437390003078
ko04972	Pancreatic secretion	4/652	111/7206	0.0439122713161
ko04070	Phosphatidylinositol signaling system	4/652	112/7206	0.0442857148448
ko04139	Mitophagy - yeast	7/652	37/7206	0.0452017114892
ko04650	Natural killer cell mediated cytotoxicity	3/652	97/7206	0.0468493264878
ko04310	Wnt signaling pathway	24/652	181/7206	0.0492946695199