ko pathway ratio_in_study ratio_in_pop p_value ko05340 Primary immunodeficiency 9/104 30/7206 2.12898369386e-10 ko04060 Cytokine-cytokine receptor interaction 17/104 191/7206 1.40789187787e-09 ko05140 Leishmaniasis 10/104 75/7206 9.62117963865e-08 ko05145 Toxoplasmosis 12/104 126/7206 2.13479318405e-07 ko04659 Th17 cell differentiation 11/104 106/7206 2.94842262837e-07 ko05152 Tuberculosis 14/104 187/7206 3.9731791036e-07 ko05150 Staphylococcus aureus infection 7/104 36/7206 6.30091992208e-07 ko05330 Allograft rejection 6/104 24/7206 8.52237630303e-07 ko04650 Natural killer cell mediated cytotoxicity 10/104 97/7206 1.12192584763e-06 ko04612 Antigen processing and presentation 9/104 77/7206 1.36896278181e-06 ko04660 T cell receptor signaling pathway 11/104 124/7206 1.44613039292e-06 ko05320 Autoimmune thyroid disease 6/104 29/7206 2.83677485905e-06 ko05310 Asthma 5/104 17/7206 3.06544601772e-06 ko04658 Th1 and Th2 cell differentiation 9/104 96/7206 8.76832096958e-06 ko05321 Inflammatory bowel disease (IBD) 7/104 56/7206 1.3818467153e-05 ko04380 Osteoclast differentiation 10/104 134/7206 2.08929170119e-05 ko05164 Influenza A 11/104 167/7206 2.57678240855e-05 ko04640 Hematopoietic cell lineage 7/104 64/7206 3.3677211787e-05 ko05162 Measles 9/104 120/7206 5.30973916877e-05 ko04064 NF-kappa B signaling pathway 8/104 96/7206 6.66865056115e-05 ko04620 Toll-like receptor signaling pathway 8/104 100/7206 8.9242269621e-05 ko05332 Graft-versus-host disease 4/104 18/7206 0.000107236122686 ko04630 Jak-STAT signaling pathway 9/104 132/7206 0.000111640848199 ko04664 Fc epsilon RI signaling pathway 7/104 77/7206 0.000111831208965 ko05416 Viral myocarditis 6/104 55/7206 0.000127789267852 ko04672 Intestinal immune network for IgA production 5/104 37/7206 0.000171681453115 ko05168 Herpes simplex infection 10/104 182/7206 0.000275673911605 ko04145 Phagosome 9/104 162/7206 0.00051971330052 ko04514 Cell adhesion molecules (CAMs) 8/104 130/7206 0.000545597419572 ko04062 Chemokine signaling pathway 10/104 201/7206 0.000607400347894 ko04610 Complement and coagulation cascades 6/104 79/7206 0.000926842417208 ko04940 Type I diabetes mellitus 4/104 32/7206 0.00107903811766 ko04666 Fc gamma R-mediated phagocytosis 7/104 122/7206 0.00183490666299 ko04611 Platelet activation 8/104 163/7206 0.00235932465794 ko05144 Malaria 4/104 45/7206 0.00387377879691 ko04217 Necroptosis 8/104 178/7206 0.0040567429526 ko04670 Leukocyte transendothelial migration 7/104 151/7206 0.00601672263274 ko05322 Systemic lupus erythematosus 7/104 151/7206 0.00601672263274 ko05167 Kaposi's sarcoma-associated herpesvirus infection 8/104 191/7206 0.00618405293114 ko03050 Proteasome 4/104 54/7206 0.00744891583114 ko05133 Pertussis 5/104 87/7206 0.00824468317968 ko04662 B cell receptor signaling pathway 5/104 88/7206 0.00864328319265 ko05323 Rheumatoid arthritis 5/104 89/7206 0.00905505627507 ko05169 Epstein-Barr virus infection 8/104 206/7206 0.00959366659047 ko04621 NOD-like receptor signaling pathway 6/104 157/7206 0.0256464750536 ko00120 Primary bile acid biosynthesis 2/104 20/7206 0.033102010526 ko00590 Arachidonic acid metabolism 3/104 52/7206 0.0387615196101 ko05142 Chagas disease (American trypanosomiasis) 5/104 130/7206 0.0394485900823