ko pathway ratio_in_study ratio_in_pop p_value ko04512 ECM-receptor interaction 29/409 79/7206 6.74508946906e-17 ko05410 Hypertrophic cardiomyopathy (HCM) 32/409 100/7206 1.67700094325e-16 ko04260 Cardiac muscle contraction 30/409 98/7206 5.97911944691e-15 ko05414 Dilated cardiomyopathy 31/409 112/7206 4.62409329915e-14 ko04974 Protein digestion and absorption 28/409 96/7206 1.93031270477e-13 ko04510 Focal adhesion 44/409 240/7206 1.87761590033e-12 ko05010 Alzheimer's disease 37/409 202/7206 1.25395884149e-10 ko04261 Adrenergic signaling in cardiomyocytes 36/409 205/7206 7.68308043507e-10 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 21/409 79/7206 1.44262841941e-09 ko01200 Carbon metabolism 27/409 128/7206 1.80626885311e-09 ko00020 Citrate cycle (TCA cycle) 14/409 35/7206 2.24052883946e-09 ko00010 Glycolysis / Gluconeogenesis 18/409 74/7206 9.83528665396e-08 ko00190 Oxidative phosphorylation 24/409 127/7206 1.37296629423e-07 ko04020 Calcium signaling pathway 37/409 265/7206 3.90192249814e-07 ko05012 Parkinson's disease 26/409 155/7206 4.86157487296e-07 ko05416 Viral myocarditis 14/409 55/7206 1.47441288282e-06 ko05016 Huntington's disease 30/409 215/7206 3.63798413281e-06 ko04022 cGMP-PKG signaling pathway 29/409 216/7206 1.41237407013e-05 ko04922 Glucagon signaling pathway 20/409 128/7206 3.05228369295e-05 ko00620 Pyruvate metabolism 11/409 46/7206 3.77381410432e-05 ko04921 Oxytocin signaling pathway 27/409 209/7206 5.01632260501e-05 ko04151 PI3K-Akt signaling pathway 41/409 390/7206 0.000105442431559 ko04932 Non-alcoholic fatty liver disease (NAFLD) 23/409 182/7206 0.000254866757391 ko00710 Carbon fixation in photosynthetic organisms 7/409 27/7206 0.000593605594846 ko00500 Starch and sucrose metabolism 8/409 35/7206 0.000609236618912 ko05034 Alcoholism 3/409 238/7206 0.000885938713873 ko01230 Biosynthesis of amino acids 13/409 85/7206 0.0009182447097 ko04062 Chemokine signaling pathway 2/409 201/7206 0.00101198541938 ko03013 RNA transport 1/409 166/7206 0.00104117401829 ko04371 Apelin signaling pathway 21/409 177/7206 0.00134240007834 ko04142 Lysosome 1/409 151/7206 0.00222679836168 ko00680 Methane metabolism 7/409 34/7206 0.00254884163345 ko03040 Spliceosome 1/409 145/7206 0.00324953224113 ko05146 Amoebiasis 13/409 99/7206 0.00374068927095 ko04964 Proximal tubule bicarbonate reclamation 6/409 29/7206 0.0050148121812 ko04550 Signaling pathways regulating pluripotency of stem cells 2/409 165/7206 0.00606304858019 ko04072 Phospholipase D signaling pathway 3/409 197/7206 0.00705257638819 ko00030 Pentose phosphate pathway 6/409 32/7206 0.00828649316268 ko04140 Autophagy - animal 2/409 164/7206 0.00905377576995 ko00350 Tyrosine metabolism 6/409 33/7206 0.00965553628755 ko04810 Regulation of actin cytoskeleton 25/409 264/7206 0.00985978259162 ko04150 mTOR signaling pathway 3/409 184/7206 0.0139327793769 ko05203 Viral carcinogenesis 7/409 277/7206 0.0166754086915 ko05032 Morphine addiction 1/409 110/7206 0.0210014420035 ko04070 Phosphatidylinositol signaling system 1/409 112/7206 0.0212747038865 ko01210 2-Oxocarboxylic acid metabolism 4/409 20/7206 0.0240050979745 ko00280 Valine, leucine and isoleucine degradation 7/409 54/7206 0.0318057973116 ko04270 Vascular smooth muscle contraction 15/409 154/7206 0.0341922490654 ko04621 NOD-like receptor signaling pathway 3/409 157/7206 0.0351917339798 ko05144 Malaria 6/409 45/7206 0.0402294800931 ko00760 Nicotinate and nicotinamide metabolism 5/409 34/7206 0.0410931194904 ko00640 Propanoate metabolism 5/409 34/7206 0.0410931194904 ko00220 Arginine biosynthesis 4/409 24/7206 0.0440871703811