ko pathway ratio_in_study ratio_in_pop p_value ko03008 Ribosome biogenesis in eukaryotes 27/288 79/7206 8.33663014609e-19 ko04110 Cell cycle 31/288 145/7206 6.03023945289e-15 ko03040 Spliceosome 30/288 145/7206 4.31688883269e-14 ko03440 Homologous recombination 16/288 41/7206 1.17397857861e-12 ko04111 Cell cycle - yeast 22/288 90/7206 3.57792745421e-12 ko03013 RNA transport 27/288 166/7206 3.07927196617e-10 ko05322 Systemic lupus erythematosus 25/288 151/7206 9.86132283933e-10 ko03460 Fanconi anemia pathway 14/288 51/7206 6.60731269398e-09 ko04113 Meiosis - yeast 15/288 70/7206 7.31054368655e-08 ko05034 Alcoholism 25/288 238/7206 8.14837234751e-06 ko03410 Base excision repair 9/288 38/7206 1.34658508869e-05 ko03018 RNA degradation 13/288 84/7206 2.46929028532e-05 ko04114 Oocyte meiosis 16/288 139/7206 0.00012419862415 ko04914 Progesterone-mediated oocyte maturation 13/288 104/7206 0.000235687823988 ko03030 DNA replication 7/288 38/7206 0.000657442860123 ko05203 Viral carcinogenesis 23/288 277/7206 0.000795494046602 ko04510 Focal adhesion 1/288 240/7206 0.0011140533744 ko00240 Pyrimidine metabolism 12/288 110/7206 0.00139649550783 ko04024 cAMP signaling pathway 2/288 279/7206 0.00151567257417 ko04014 Ras signaling pathway 2/288 279/7206 0.00151567257417 ko04810 Regulation of actin cytoskeleton 2/288 264/7206 0.0021546083873 ko04022 cGMP-PKG signaling pathway 1/288 216/7206 0.00232258497973 ko04218 Cellular senescence 16/288 177/7206 0.00251092776355 ko04115 p53 signaling pathway 9/288 74/7206 0.00258858172914 ko04151 PI3K-Akt signaling pathway 5/288 390/7206 0.00303403999568 ko05166 HTLV-I infection 22/288 292/7206 0.00351066458636 ko03015 mRNA surveillance pathway 10/288 93/7206 0.0038199089482 ko04072 Phospholipase D signaling pathway 1/288 197/7206 0.00494171249072 ko03020 RNA polymerase 5/288 29/7206 0.00531102825117 ko03420 Nucleotide excision repair 6/288 46/7206 0.00943204531988 ko03430 Mismatch repair 4/288 22/7206 0.0103396907933 ko05016 Huntington's disease 2/288 215/7206 0.0125750316383 ko04261 Adrenergic signaling in cardiomyocytes 2/288 205/7206 0.0177529906316 ko04921 Oxytocin signaling pathway 2/288 209/7206 0.0180391393995 ko04010 MAPK signaling pathway 5/288 321/7206 0.018730023622 ko05012 Parkinson's disease 1/288 155/7206 0.021674472092 ko04621 NOD-like receptor signaling pathway 1/288 157/7206 0.0217575358128 ko04152 AMPK signaling pathway 1/288 161/7206 0.0223434293608 ko04360 Axon guidance 3/288 233/7206 0.0261349142321 ko04015 Rap1 signaling pathway 4/288 278/7206 0.0268350719507 ko04724 Glutamatergic synapse 1/288 152/7206 0.0325129082072 ko04728 Dopaminergic synapse 2/288 185/7206 0.0350475006874 ko05152 Tuberculosis 2/288 187/7206 0.0352777750376 ko04530 Tight junction 3/288 228/7206 0.0367126847699 ko04122 Sulfur relay system 2/288 8/7206 0.0380011702994 ko04713 Circadian entrainment 1/288 136/7206 0.044948691353 ko04931 Insulin resistance 1/288 137/7206 0.0450800394234 ko04723 Retrograde endocannabinoid signaling 2/288 175/7206 0.0489874740909 ko04371 Apelin signaling pathway 2/288 177/7206 0.0493356750613