ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	162/930	423/7206	7.44029384258e-43
ko04724	Glutamatergic synapse	80/930	152/7206	1.18526443828e-32
ko05033	Nicotine addiction	46/930	56/7206	4.56473179082e-32
ko05032	Morphine addiction	63/930	110/7206	1.12662443017e-28
ko04727	GABAergic synapse	59/930	110/7206	7.19904729509e-25
ko04728	Dopaminergic synapse	75/930	185/7206	1.28707096807e-21
ko04713	Circadian entrainment	62/930	136/7206	3.29147546438e-21
ko04723	Retrograde endocannabinoid signaling	70/930	175/7206	7.59044515464e-20
ko04721	Synaptic vesicle cycle	44/930	80/7206	2.11129429013e-19
ko04725	Cholinergic synapse	65/930	160/7206	6.41764453662e-19
ko04024	cAMP signaling pathway	89/930	279/7206	3.32807559821e-17
ko04911	Insulin secretion	51/930	117/7206	1.26703283733e-16
ko04921	Oxytocin signaling pathway	67/930	209/7206	2.12420371756e-13
ko04742	Taste transduction	31/930	61/7206	8.39676178161e-13
ko04261	Adrenergic signaling in cardiomyocytes	65/930	205/7206	1.1932158135e-12
ko04020	Calcium signaling pathway	75/930	265/7206	9.4841708338e-12
ko05031	Amphetamine addiction	36/930	91/7206	1.24238275233e-10
ko04726	Serotonergic synapse	46/930	137/7206	2.46243598691e-10
ko04720	Long-term potentiation	36/930	99/7206	1.95060189825e-09
ko05030	Cocaine addiction	28/930	73/7206	3.23926760319e-08
ko04925	Aldosterone synthesis and secretion	35/930	105/7206	4.36535091755e-08
ko03040	Spliceosome	1/930	145/7206	5.76181645423e-08
ko05203	Viral carcinogenesis	10/930	277/7206	1.20846264014e-07
ko04970	Salivary secretion	32/930	95/7206	1.2563095552e-07
ko04744	Phototransduction	17/930	36/7206	5.14144457419e-07
ko04072	Phospholipase D signaling pathway	50/930	197/7206	1.40174873445e-06
ko04010	MAPK signaling pathway	72/930	321/7206	1.40542864146e-06
ko04360	Axon guidance	56/930	233/7206	2.20299878041e-06
ko04972	Pancreatic secretion	33/930	111/7206	2.24047932204e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/930	74/7206	2.81873288909e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/930	79/7206	3.12480172758e-06
ko04971	Gastric acid secretion	30/930	98/7206	4.24987561245e-06
ko04060	Cytokine-cytokine receptor interaction	6/930	191/7206	4.89475206764e-06
ko04514	Cell adhesion molecules (CAMs)	36/930	130/7206	7.29680003825e-06
ko05168	Herpes simplex infection	6/930	182/7206	9.74415516945e-06
ko04022	cGMP-PKG signaling pathway	51/930	216/7206	1.1496800903e-05
ko04260	Cardiac muscle contraction	28/930	98/7206	4.61118486336e-05
ko03013	RNA transport	6/930	166/7206	5.63269598803e-05
ko05322	Systemic lupus erythematosus	5/930	151/7206	7.0000846003e-05
ko05110	Vibrio cholerae infection	20/930	63/7206	7.59737294082e-05
ko05414	Dilated cardiomyopathy	30/930	112/7206	8.17695570225e-05
ko04110	Cell cycle	5/930	145/7206	0.000141754479617
ko04745	Phototransduction - fly	14/930	38/7206	0.000154532202122
ko04070	Phosphatidylinositol signaling system	29/930	112/7206	0.000167520226403
ko04966	Collecting duct acid secretion	11/930	26/7206	0.000189786313342
ko04915	Estrogen signaling pathway	32/930	131/7206	0.000299177762365
ko05205	Proteoglycans in cancer	17/930	271/7206	0.000420438882422
ko04141	Protein processing in endoplasmic reticulum	9/930	184/7206	0.000477287099337
ko04740	Olfactory transduction	22/930	80/7206	0.000546626797518
ko05164	Influenza A	8/930	167/7206	0.000638516310608
ko04730	Long-term depression	21/930	78/7206	0.00090053691859
ko04350	TGF-beta signaling pathway	3/930	103/7206	0.000907456302547
ko04540	Gap junction	30/930	128/7206	0.00118367639536
ko04621	NOD-like receptor signaling pathway	8/930	157/7206	0.00162460619936
ko03008	Ribosome biogenesis in eukaryotes	2/930	79/7206	0.00218140304406
ko05410	Hypertrophic cardiomyopathy (HCM)	24/930	100/7206	0.00224908606196
ko04640	Hematopoietic cell lineage	1/930	64/7206	0.00235614019271
ko04750	Inflammatory mediator regulation of TRP channels	28/930	122/7206	0.00235748177833
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/930	59/7206	0.00283712107618
ko05169	Epstein-Barr virus infection	13/930	206/7206	0.00295177857761
ko04120	Ubiquitin mediated proteolysis	7/930	138/7206	0.00306708222123
ko04612	Antigen processing and presentation	2/930	77/7206	0.00317582149201
ko04976	Bile secretion	20/930	80/7206	0.00356830740817
ko05140	Leishmaniasis	2/930	75/7206	0.00473515575809
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/930	14/7206	0.00543454493862
ko05162	Measles	6/930	120/7206	0.00579493214253
ko04214	Apoptosis - fly	2/930	72/7206	0.00689738837162
ko05321	Inflammatory bowel disease (IBD)	1/930	56/7206	0.00787592035236
ko04064	NF-kappa B signaling pathway	4/930	96/7206	0.00822158883645
ko04924	Renin secretion	20/930	86/7206	0.00848535844072
ko04918	Thyroid hormone synthesis	20/930	86/7206	0.00848535844072
ko00590	Arachidonic acid metabolism	1/930	52/7206	0.0114509490728
ko04015	Rap1 signaling pathway	50/930	278/7206	0.0134515375048
ko04014	Ras signaling pathway	50/930	279/7206	0.0137343502366
ko05161	Hepatitis B	12/930	173/7206	0.0155241043598
ko04146	Peroxisome	4/930	89/7206	0.0156680853574
ko00260	Glycine, serine and threonine metabolism	1/930	48/7206	0.01685786571
ko04630	Jak-STAT signaling pathway	8/930	132/7206	0.0174076305039
ko04210	Apoptosis	13/930	180/7206	0.0179561910447
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/930	182/7206	0.018081235018
ko00330	Arginine and proline metabolism	2/930	61/7206	0.0199094187757
ko05202	Transcriptional misregulation in cancer	14/930	188/7206	0.0205287206627
ko00310	Lysine degradation	3/930	73/7206	0.0211613137141
ko00230	Purine metabolism	36/930	194/7206	0.0221652621054
ko04930	Type II diabetes mellitus	13/930	54/7206	0.0226246631871
ko04217	Necroptosis	13/930	178/7206	0.022998798828
ko05016	Huntington's disease	17/930	215/7206	0.0231418418222
ko04071	Sphingolipid signaling pathway	31/930	162/7206	0.0234845924168
ko04923	Regulation of lipolysis in adipocytes	17/930	77/7206	0.0244662975939
ko00071	Fatty acid degradation	1/930	45/7206	0.0248486483289
ko03420	Nucleotide excision repair	1/930	46/7206	0.0250895539551
ko04550	Signaling pathways regulating pluripotency of stem cells	12/930	165/7206	0.0255836714371
ko00512	Mucin type O-glycan biosynthesis	8/930	29/7206	0.0266195262132
ko04964	Proximal tubule bicarbonate reclamation	8/930	29/7206	0.0266195262132
ko03320	PPAR signaling pathway	3/930	69/7206	0.0294209433162
ko04137	Mitophagy - animal	4/930	82/7206	0.0295166604535
ko04371	Apelin signaling pathway	33/930	177/7206	0.0300839002036
ko05215	Prostate cancer	7/930	111/7206	0.0324314470827
ko04960	Aldosterone-regulated sodium reabsorption	10/930	41/7206	0.0355840449675
ko05231	Choline metabolism in cancer	26/930	134/7206	0.0360665794548
ko04916	Melanogenesis	27/930	142/7206	0.0417537923859
ko00240	Pyrimidine metabolism	7/930	110/7206	0.0432822730957
ko04658	Th1 and Th2 cell differentiation	6/930	96/7206	0.0467794938901