ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	158/934	423/7206	6.81127895834e-40
ko04724	Glutamatergic synapse	76/934	152/7206	5.57257046914e-29
ko05033	Nicotine addiction	42/934	56/7206	2.24919556283e-26
ko04721	Synaptic vesicle cycle	49/934	80/7206	2.81034178281e-24
ko05032	Morphine addiction	58/934	110/7206	7.33475398702e-24
ko04727	GABAergic synapse	57/934	110/7206	5.72341784618e-23
ko04728	Dopaminergic synapse	75/934	185/7206	1.67922902187e-21
ko04713	Circadian entrainment	61/934	136/7206	2.44322835872e-20
ko04723	Retrograde endocannabinoid signaling	68/934	175/7206	2.12649628513e-18
ko04725	Cholinergic synapse	64/934	160/7206	3.90696543848e-18
ko04024	cAMP signaling pathway	89/934	279/7206	4.01557632389e-17
ko04921	Oxytocin signaling pathway	70/934	209/7206	6.12696459138e-15
ko04020	Calcium signaling pathway	81/934	265/7206	1.69524380341e-14
ko04726	Serotonergic synapse	52/934	137/7206	7.53593857045e-14
ko04744	Phototransduction	24/934	36/7206	1.03003525032e-13
ko04742	Taste transduction	32/934	61/7206	1.26731647976e-13
ko04911	Insulin secretion	46/934	117/7206	4.83088443544e-13
ko04261	Adrenergic signaling in cardiomyocytes	63/934	205/7206	1.14959300178e-11
ko05031	Amphetamine addiction	37/934	91/7206	2.98229979421e-11
ko04720	Long-term potentiation	37/934	99/7206	5.33597116903e-10
ko04966	Collecting duct acid secretion	16/934	26/7206	8.39028103412e-09
ko05203	Viral carcinogenesis	10/934	277/7206	1.23108220907e-07
ko04970	Salivary secretion	32/934	95/7206	1.39006436894e-07
ko03040	Spliceosome	2/934	145/7206	5.98186264773e-07
ko04971	Gastric acid secretion	31/934	98/7206	1.04731710863e-06
ko04925	Aldosterone synthesis and secretion	32/934	105/7206	2.18217988619e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/934	74/7206	3.05091311872e-06
ko04022	cGMP-PKG signaling pathway	52/934	216/7206	6.90796541895e-06
ko04745	Phototransduction - fly	16/934	38/7206	7.6363912619e-06
ko05322	Systemic lupus erythematosus	4/934	151/7206	1.33497645759e-05
ko04360	Axon guidance	54/934	233/7206	1.53238010513e-05
ko04060	Cytokine-cytokine receptor interaction	7/934	191/7206	1.5709606827e-05
ko04626	Plant-pathogen interaction	10/934	18/7206	2.08775103819e-05
ko05110	Vibrio cholerae infection	21/934	63/7206	2.3617517501e-05
ko05030	Cocaine addiction	23/934	73/7206	2.75462867701e-05
ko04010	MAPK signaling pathway	67/934	321/7206	5.58046533476e-05
ko05164	Influenza A	6/934	167/7206	5.67632240412e-05
ko04120	Ubiquitin mediated proteolysis	4/934	138/7206	5.83851228948e-05
ko04070	Phosphatidylinositol signaling system	30/934	112/7206	8.48179983643e-05
ko05162	Measles	3/934	120/7206	9.60735836617e-05
ko04260	Cardiac muscle contraction	27/934	98/7206	9.96928481307e-05
ko04730	Long-term depression	23/934	78/7206	0.000106697341875
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/934	14/7206	0.000112788927201
ko05169	Epstein-Barr virus infection	10/934	206/7206	0.00013264688721
ko04740	Olfactory transduction	23/934	80/7206	0.000149038281079
ko04972	Pancreatic secretion	29/934	111/7206	0.000156477227169
ko04540	Gap junction	32/934	128/7206	0.000167480524866
ko05168	Herpes simplex infection	8/934	182/7206	0.000184297594838
ko03013	RNA transport	7/934	166/7206	0.000239467279562
ko04924	Renin secretion	24/934	86/7206	0.000246506957637
ko04610	Complement and coagulation cascades	1/934	79/7206	0.000318405431015
ko05161	Hepatitis B	8/934	173/7206	0.000337026477138
ko04072	Phospholipase D signaling pathway	43/934	197/7206	0.000502506030438
ko05414	Dilated cardiomyopathy	28/934	112/7206	0.000517546735065
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/934	79/7206	0.000519005758924
ko04750	Inflammatory mediator regulation of TRP channels	30/934	122/7206	0.000536620517141
ko04514	Cell adhesion molecules (CAMs)	31/934	130/7206	0.000540743163761
ko04621	NOD-like receptor signaling pathway	7/934	157/7206	0.000651652176545
ko05205	Proteoglycans in cancer	18/934	271/7206	0.000861869112982
ko04141	Protein processing in endoplasmic reticulum	10/934	184/7206	0.00113920365954
ko05120	Epithelial cell signaling in Helicobacter pylori infection	23/934	92/7206	0.00148743274469
ko04064	NF-kappa B signaling pathway	3/934	96/7206	0.00185456508187
ko03008	Ribosome biogenesis in eukaryotes	2/934	79/7206	0.0021700704586
ko04964	Proximal tubule bicarbonate reclamation	10/934	29/7206	0.00249175400283
ko01524	Platinum drug resistance	2/934	76/7206	0.00315383973342
ko04612	Antigen processing and presentation	2/934	77/7206	0.0031831379524
ko04915	Estrogen signaling pathway	29/934	131/7206	0.00346979244938
ko04014	Ras signaling pathway	53/934	279/7206	0.00348715832407
ko04976	Bile secretion	20/934	80/7206	0.00363951093434
ko04146	Peroxisome	3/934	89/7206	0.00373850293656
ko05215	Prostate cancer	5/934	111/7206	0.00420106588762
ko05166	HTLV-I infection	22/934	292/7206	0.00422415708551
ko04510	Focal adhesion	17/934	240/7206	0.00440479914076
ko04114	Oocyte meiosis	30/934	139/7206	0.0045702902178
ko00310	Lysine degradation	2/934	73/7206	0.00457706573141
ko05140	Leishmaniasis	2/934	75/7206	0.00477771526803
ko04110	Cell cycle	8/934	145/7206	0.00552375522413
ko04668	TNF signaling pathway	6/934	120/7206	0.005783096357
ko00240	Pyrimidine metabolism	5/934	110/7206	0.00593017072047
ko04214	Apoptosis - fly	2/934	72/7206	0.00696237657706
ko00280	Valine, leucine and isoleucine degradation	1/934	54/7206	0.00769873433701
ko00480	Glutathione metabolism	1/934	55/7206	0.00772567415567
ko05321	Inflammatory bowel disease (IBD)	1/934	56/7206	0.00791869225147
ko04371	Apelin signaling pathway	35/934	177/7206	0.00892401059211
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/934	59/7206	0.00954979948023
ko05410	Hypertrophic cardiomyopathy (HCM)	22/934	100/7206	0.0103448799852
ko05323	Rheumatoid arthritis	20/934	89/7206	0.0107831042974
ko00590	Arachidonic acid metabolism	1/934	52/7206	0.011464161199
ko05222	Small cell lung cancer	4/934	89/7206	0.0157911169925
ko05219	Bladder cancer	1/934	48/7206	0.0168193330488
ko04630	Jak-STAT signaling pathway	8/934	132/7206	0.0175565203865
ko04210	Apoptosis	13/934	180/7206	0.0179287485082
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/934	182/7206	0.0182046081812
ko04670	Leukocyte transendothelial migration	10/934	151/7206	0.0191340784251
ko00330	Arginine and proline metabolism	2/934	61/7206	0.0199502128068
ko04115	p53 signaling pathway	3/934	74/7206	0.0217340052867
ko05145	Toxoplasmosis	8/934	126/7206	0.0225364409192
ko05206	MicroRNAs in cancer	13/934	177/7206	0.022934361167
ko05034	Alcoholism	43/934	238/7206	0.0234036763463
ko05144	Malaria	1/934	45/7206	0.0248152999219
ko00071	Fatty acid degradation	1/934	45/7206	0.0248152999219
ko03420	Nucleotide excision repair	1/934	46/7206	0.0251484470724
ko05010	Alzheimer's disease	37/934	202/7206	0.0254911137255
ko00910	Nitrogen metabolism	6/934	19/7206	0.0284248199296
ko05200	Pathways in cancer	48/934	492/7206	0.0308122694995
ko04140	Autophagy - animal	12/934	164/7206	0.0332268269529
ko04016	MAPK signaling pathway - plant	6/934	20/7206	0.0362871815484
ko00983	Drug metabolism - other enzymes	1/934	42/7206	0.0365609578931
ko03022	Basal transcription factors	1/934	44/7206	0.038421550857
ko00230	Purine metabolism	35/934	194/7206	0.0389762332042
ko04912	GnRH signaling pathway	24/934	122/7206	0.0398729758933
ko04068	FoxO signaling pathway	13/934	167/7206	0.0467065870236