ko pathway ratio_in_study ratio_in_pop p_value ko05217 Basal cell carcinoma 24/316 68/7206 2.8226925495e-16 ko04550 Signaling pathways regulating pluripotency of stem cells 33/316 165/7206 9.11787131215e-14 ko04360 Axon guidance 39/316 233/7206 2.00461126577e-13 ko05224 Breast cancer 29/316 174/7206 3.346441871e-10 ko04340 Hedgehog signaling pathway 16/316 58/7206 1.92250927608e-09 ko04390 Hippo signaling pathway 28/316 188/7206 9.40887866045e-09 ko04330 Notch signaling pathway 13/316 62/7206 2.06256728208e-06 ko05205 Proteoglycans in cancer 30/316 271/7206 2.24835920299e-06 ko04950 Maturity onset diabetes of the young 9/316 29/7206 2.46472792715e-06 ko04310 Wnt signaling pathway 23/316 181/7206 3.61729547129e-06 ko04391 Hippo signaling pathway - fly 15/316 90/7206 7.06365125237e-06 ko05200 Pathways in cancer 43/316 492/7206 1.03071239874e-05 ko04145 Phagosome 19/316 162/7206 7.92121755426e-05 ko04512 ECM-receptor interaction 12/316 79/7206 0.00014905442267 ko04612 Antigen processing and presentation 11/316 77/7206 0.000484151562247 ko04080 Neuroactive ligand-receptor interaction 6/316 423/7206 0.000838835394749 ko04341 Hedgehog signaling pathway - fly 7/316 38/7206 0.00113793768207 ko04916 Melanogenesis 15/316 142/7206 0.00133838775073 ko04514 Cell adhesion molecules (CAMs) 14/316 130/7206 0.00159652398566 ko05130 Pathogenic Escherichia coli infection 10/316 77/7206 0.00183307466243 ko04151 PI3K-Akt signaling pathway 30/316 390/7206 0.00216230759293 ko04072 Phospholipase D signaling pathway 1/316 197/7206 0.00230831704269 ko04974 Protein digestion and absorption 11/316 96/7206 0.0030491878449 ko05168 Herpes simplex infection 1/316 182/7206 0.00498956323073 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/316 182/7206 0.00498956323073 ko05202 Transcriptional misregulation in cancer 17/316 188/7206 0.00547494700915 ko00514 Other types of O-glycan biosynthesis 5/316 30/7206 0.00906916149122 ko05166 HTLV-I infection 22/316 292/7206 0.012219980609 ko05206 MicroRNAs in cancer 15/316 177/7206 0.0137403755943 ko04724 Glutamatergic synapse 1/316 152/7206 0.014957353842 ko05222 Small cell lung cancer 9/316 89/7206 0.0155879856317 ko04510 Focal adhesion 18/316 240/7206 0.0235771741973 ko03410 Base excision repair 5/316 38/7206 0.0240438901722 ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 4/316 26/7206 0.0252910131302 ko04144 Endocytosis 7/316 342/7206 0.0292839918365 ko04120 Ubiquitin mediated proteolysis 1/316 138/7206 0.0321316960908 ko04013 MAPK signaling pathway - fly 10/316 115/7206 0.034547078496 ko05034 Alcoholism 4/316 238/7206 0.0351807425124 ko05010 Alzheimer's disease 3/316 202/7206 0.0357759227421 ko04062 Chemokine signaling pathway 3/316 201/7206 0.0357773173856 ko04723 Retrograde endocannabinoid signaling 2/316 175/7206 0.0364301111656 ko04921 Oxytocin signaling pathway 3/316 209/7206 0.0369537760197 ko04658 Th1 and Th2 cell differentiation 9/316 96/7206 0.0375177715509 ko04020 Calcium signaling pathway 5/316 265/7206 0.0450661773134 ko00190 Oxidative phosphorylation 1/316 127/7206 0.0453982123893 ko01200 Carbon metabolism 1/316 128/7206 0.0457850654517 ko04350 TGF-beta signaling pathway 9/316 103/7206 0.0458394423094 ko00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 3/316 19/7206 0.0480848431689 ko04725 Cholinergic synapse 2/316 160/7206 0.0488559352501 ko00230 Purine metabolism 3/316 194/7206 0.0490721063977