ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	151/981	423/7206	9.42521456794e-33
ko04724	Glutamatergic synapse	69/981	152/7206	5.43865724831e-22
ko05033	Nicotine addiction	37/981	56/7206	1.56395746667e-19
ko05032	Morphine addiction	52/981	110/7206	8.53321197035e-18
ko04713	Circadian entrainment	58/981	136/7206	4.431899248e-17
ko04721	Synaptic vesicle cycle	42/981	80/7206	1.04173480476e-16
ko04727	GABAergic synapse	50/981	110/7206	2.85049241967e-16
ko04728	Dopaminergic synapse	68/981	185/7206	8.86787806543e-16
ko04020	Calcium signaling pathway	83/981	265/7206	3.21661367205e-14
ko04725	Cholinergic synapse	57/981	160/7206	9.49696835971e-13
ko04723	Retrograde endocannabinoid signaling	60/981	175/7206	1.59502825178e-12
ko04911	Insulin secretion	46/981	117/7206	2.90137136414e-12
ko04921	Oxytocin signaling pathway	67/981	209/7206	3.88023357183e-12
ko04024	cAMP signaling pathway	81/981	279/7206	6.37349351141e-12
ko04726	Serotonergic synapse	48/981	137/7206	1.21391397396e-10
ko05031	Amphetamine addiction	34/981	91/7206	9.84787574682e-09
ko04744	Phototransduction	19/981	36/7206	2.58310035547e-08
ko04970	Salivary secretion	34/981	95/7206	3.47181395513e-08
ko04720	Long-term potentiation	34/981	99/7206	1.11573746844e-07
ko04261	Adrenergic signaling in cardiomyocytes	56/981	205/7206	1.35259109962e-07
ko03010	Ribosome	1/981	129/7206	1.82791831899e-07
ko05322	Systemic lupus erythematosus	3/981	151/7206	9.02282306519e-07
ko04966	Collecting duct acid secretion	14/981	26/7206	1.34573137407e-06
ko04925	Aldosterone synthesis and secretion	33/981	105/7206	1.91087386012e-06
ko03040	Spliceosome	3/981	145/7206	1.97180256553e-06
ko04742	Taste transduction	23/981	61/7206	2.03571615715e-06
ko04022	cGMP-PKG signaling pathway	55/981	216/7206	2.44408992912e-06
ko04745	Phototransduction - fly	17/981	38/7206	2.8453825086e-06
ko04971	Gastric acid secretion	31/981	98/7206	3.57010676721e-06
ko05203	Viral carcinogenesis	14/981	277/7206	3.99434585933e-06
ko05168	Herpes simplex infection	7/981	182/7206	1.4809021591e-05
ko05164	Influenza A	6/981	167/7206	1.84937142352e-05
ko04120	Ubiquitin mediated proteolysis	4/981	138/7206	2.63728474392e-05
ko03013	RNA transport	6/981	166/7206	2.72488983444e-05
ko04740	Olfactory transduction	25/981	80/7206	4.19439301701e-05
ko05162	Measles	3/981	120/7206	4.29045379962e-05
ko05110	Vibrio cholerae infection	21/981	63/7206	4.98400795552e-05
ko04110	Cell cycle	5/981	145/7206	6.76025701047e-05
ko04070	Phosphatidylinositol signaling system	31/981	112/7206	7.11250961814e-05
ko05030	Cocaine addiction	23/981	73/7206	8.23107170315e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	23/981	74/7206	9.55633746177e-05
ko04010	MAPK signaling pathway	68/981	321/7206	0.000160345680628
ko05161	Hepatitis B	8/981	173/7206	0.000174027942226
ko04730	Long-term depression	23/981	78/7206	0.000197706037856
ko03008	Ribosome biogenesis in eukaryotes	1/981	79/7206	0.000202416135261
ko04964	Proximal tubule bicarbonate reclamation	12/981	29/7206	0.00021082647969
ko05166	HTLV-I infection	20/981	292/7206	0.000321186754783
ko04710	Circadian rhythm	15/981	43/7206	0.000335158952489
ko04972	Pancreatic secretion	29/981	111/7206	0.000387309845363
ko04750	Inflammatory mediator regulation of TRP channels	31/981	122/7206	0.000434267235782
ko05140	Leishmaniasis	1/981	75/7206	0.000487686775477
ko04922	Glucagon signaling pathway	31/981	128/7206	0.00101704038277
ko04626	Plant-pathogen interaction	8/981	18/7206	0.00141472354082
ko04514	Cell adhesion molecules (CAMs)	31/981	130/7206	0.00168527732225
ko04621	NOD-like receptor signaling pathway	9/981	157/7206	0.00206165123739
ko04330	Notch signaling pathway	1/981	62/7206	0.00231214640725
ko04014	Ras signaling pathway	56/981	279/7206	0.00234148694816
ko04924	Renin secretion	22/981	86/7206	0.00243646479205
ko04540	Gap junction	30/981	128/7206	0.00246108372428
ko04657	IL-17 signaling pathway	3/981	87/7206	0.00251175641729
ko05169	Epstein-Barr virus infection	14/981	206/7206	0.00262599564879
ko04630	Jak-STAT signaling pathway	7/981	132/7206	0.00296731432222
ko05215	Prostate cancer	5/981	111/7206	0.00299374872482
ko04141	Protein processing in endoplasmic reticulum	12/981	184/7206	0.00307802633354
ko04060	Cytokine-cytokine receptor interaction	13/981	191/7206	0.00371906002294
ko04072	Phospholipase D signaling pathway	41/981	197/7206	0.00431480829123
ko00520	Amino sugar and nucleotide sugar metabolism	1/981	55/7206	0.00503640873414
ko05200	Pathways in cancer	47/981	492/7206	0.00631088130657
ko04260	Cardiac muscle contraction	23/981	98/7206	0.00709490277563
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/981	14/7206	0.00710206795089
ko04510	Focal adhesion	19/981	240/7206	0.00716154599475
ko04612	Antigen processing and presentation	3/981	77/7206	0.0072980916166
ko04610	Complement and coagulation cascades	3/981	79/7206	0.00740214302976
ko04210	Apoptosis	13/981	180/7206	0.0108225333342
ko05120	Epithelial cell signaling in Helicobacter pylori infection	21/981	92/7206	0.0138273631763
ko04371	Apelin signaling pathway	36/981	177/7206	0.0139993381043
ko04064	NF-kappa B signaling pathway	5/981	96/7206	0.0152616950099
ko04550	Signaling pathways regulating pluripotency of stem cells	12/981	165/7206	0.015280382967
ko00010	Glycolysis / Gluconeogenesis	18/981	74/7206	0.015361098314
ko03420	Nucleotide excision repair	1/981	46/7206	0.016452584064
ko05205	Proteoglycans in cancer	24/981	271/7206	0.0186422826199
ko05323	Rheumatoid arthritis	20/981	89/7206	0.0191861474295
ko05016	Huntington's disease	18/981	215/7206	0.0201521520205
ko05217	Basal cell carcinoma	3/981	68/7206	0.0205289142954
ko04960	Aldosterone-regulated sodium reabsorption	11/981	41/7206	0.0207066515445
ko04270	Vascular smooth muscle contraction	31/981	154/7206	0.0232756645199
ko03022	Basal transcription factors	1/981	44/7206	0.0247565631848
ko04620	Toll-like receptor signaling pathway	6/981	100/7206	0.0262239486617
ko05133	Pertussis	5/981	87/7206	0.0273139626535
ko00280	Valine, leucine and isoleucine degradation	2/981	54/7206	0.0277294167669
ko05222	Small cell lung cancer	5/981	89/7206	0.0278485815066
ko01524	Platinum drug resistance	4/981	76/7206	0.0284480171236
ko05130	Pathogenic Escherichia coli infection	4/981	77/7206	0.0285897574425
ko05321	Inflammatory bowel disease (IBD)	2/981	56/7206	0.0286891958251
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/981	79/7206	0.0298609356107
ko04360	Axon guidance	43/981	233/7206	0.0324957352771
ko04114	Oocyte meiosis	28/981	139/7206	0.032606547545
ko04660	T cell receptor signaling pathway	9/981	124/7206	0.0344711546876
ko04658	Th1 and Th2 cell differentiation	6/981	96/7206	0.0346957821859
ko05145	Toxoplasmosis	9/981	126/7206	0.0348462695378
ko05220	Chronic myeloid leukemia	5/981	85/7206	0.0372190965299
ko04915	Estrogen signaling pathway	26/981	131/7206	0.0398520549621
ko04622	RIG-I-like receptor signaling pathway	3/981	62/7206	0.0401988324394
ko00680	Methane metabolism	9/981	34/7206	0.040870002309
ko00562	Inositol phosphate metabolism	19/981	89/7206	0.0417338779558
ko04930	Type II diabetes mellitus	13/981	54/7206	0.0426909646264
ko05206	MicroRNAs in cancer	15/981	177/7206	0.0451846335358
ko00240	Pyrimidine metabolism	8/981	110/7206	0.0497115150257
ko04976	Bile secretion	17/981	80/7206	0.0497840187971