ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 32/274 191/7206 6.85195944102e-13 ko04380 Osteoclast differentiation 26/274 134/7206 3.52552117965e-12 ko04610 Complement and coagulation cascades 17/274 79/7206 4.23229906408e-09 ko05150 Staphylococcus aureus infection 10/274 36/7206 5.67659468225e-07 ko05140 Leishmaniasis 14/274 75/7206 6.60890596178e-07 ko05164 Influenza A 21/274 167/7206 1.19002917536e-06 ko05152 Tuberculosis 22/274 187/7206 2.05934215074e-06 ko05162 Measles 17/274 120/7206 2.45864971316e-06 ko04650 Natural killer cell mediated cytotoxicity 15/274 97/7206 3.20088019838e-06 ko04621 NOD-like receptor signaling pathway 19/274 157/7206 6.90491990698e-06 ko04672 Intestinal immune network for IgA production 9/274 37/7206 7.10207836911e-06 ko05340 Primary immunodeficiency 8/274 30/7206 1.11347466821e-05 ko05321 Inflammatory bowel disease (IBD) 10/274 56/7206 4.05378514856e-05 ko05145 Toxoplasmosis 15/274 126/7206 7.89024806201e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 19/274 191/7206 0.000109644108215 ko04630 Jak-STAT signaling pathway 15/274 132/7206 0.000134557476175 ko04933 AGE-RAGE signaling pathway in diabetic complications 15/274 135/7206 0.000173417059973 ko04659 Th17 cell differentiation 13/274 106/7206 0.000174730431905 ko05168 Herpes simplex infection 18/274 182/7206 0.000179043477002 ko05132 Salmonella infection 12/274 98/7206 0.000314172038651 ko04611 Platelet activation 16/274 163/7206 0.000444585998217 ko05160 Hepatitis C 15/274 153/7206 0.000676746697091 ko04666 Fc gamma R-mediated phagocytosis 13/274 122/7206 0.000700799142126 ko04217 Necroptosis 16/274 178/7206 0.00116396464922 ko04620 Toll-like receptor signaling pathway 11/274 100/7206 0.00137603208066 ko04662 B cell receptor signaling pathway 10/274 88/7206 0.00176111288123 ko04612 Antigen processing and presentation 9/274 77/7206 0.00243541801527 ko04664 Fc epsilon RI signaling pathway 9/274 77/7206 0.00243541801527 ko04660 T cell receptor signaling pathway 12/274 124/7206 0.0025628906715 ko04640 Hematopoietic cell lineage 8/274 64/7206 0.00274798750772 ko04658 Th1 and Th2 cell differentiation 10/274 96/7206 0.0033728779598 ko05161 Hepatitis B 15/274 173/7206 0.00347965308389 ko04062 Chemokine signaling pathway 16/274 201/7206 0.00440110633725 ko05166 HTLV-I infection 21/274 292/7206 0.00440407118842 ko04145 Phagosome 14/274 162/7206 0.00510130441386 ko05133 Pertussis 9/274 87/7206 0.00556967277854 ko04668 TNF signaling pathway 11/274 120/7206 0.00577771242723 ko00120 Primary bile acid biosynthesis 4/274 20/7206 0.00611924402751 ko05323 Rheumatoid arthritis 9/274 89/7206 0.00646306583058 ko05144 Malaria 6/274 45/7206 0.00669326854031 ko05034 Alcoholism 2/274 238/7206 0.00891545358888 ko04064 NF-kappa B signaling pathway 9/274 96/7206 0.0104787397664 ko04072 Phospholipase D signaling pathway 15/274 197/7206 0.0118189915079 ko05330 Allograft rejection 4/274 24/7206 0.0119138296852 ko05131 Shigellosis 8/274 82/7206 0.0123191365471 ko05212 Pancreatic cancer 8/274 83/7206 0.0131988980025 ko04144 Endocytosis 22/274 342/7206 0.013410090452 ko05142 Chagas disease (American trypanosomiasis) 11/274 130/7206 0.0165529905358 ko05202 Transcriptional misregulation in cancer 14/274 188/7206 0.0175328207217 ko05320 Autoimmune thyroid disease 4/274 29/7206 0.0229678507922 ko04015 Rap1 signaling pathway 18/274 278/7206 0.0241646022484 ko05310 Asthma 3/274 17/7206 0.0249007647927 ko05332 Graft-versus-host disease 3/274 18/7206 0.0290603337406 ko04622 RIG-I-like receptor signaling pathway 6/274 62/7206 0.0296382343332 ko04670 Leukocyte transendothelial migration 11/274 151/7206 0.0312819265651 ko05012 Parkinson's disease 1/274 155/7206 0.0314914824082 ko05215 Prostate cancer 9/274 111/7206 0.0381108407353 ko05169 Epstein-Barr virus infection 14/274 206/7206 0.0384081453736 ko05200 Pathways in cancer 27/274 492/7206 0.0499534835833