ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	91/792	145/7206	4.40213705956e-52
ko03013	RNA transport	74/792	166/7206	6.41289749409e-29
ko04110	Cell cycle	64/792	145/7206	8.18303232496e-25
ko03440	Homologous recombination	32/792	41/7206	1.54179463001e-23
ko04111	Cell cycle - yeast	48/792	90/7206	2.36759604502e-23
ko05322	Systemic lupus erythematosus	63/792	151/7206	8.06693074802e-23
ko03460	Fanconi anemia pathway	33/792	51/7206	4.90406960241e-20
ko03030	DNA replication	28/792	38/7206	1.46434195953e-19
ko04080	Neuroactive ligand-receptor interaction	2/792	423/7206	2.22697702946e-19
ko03008	Ribosome biogenesis in eukaryotes	39/792	79/7206	1.20940818003e-17
ko03022	Basal transcription factors	27/792	44/7206	9.34371981394e-16
ko04113	Meiosis - yeast	33/792	70/7206	2.24418075088e-14
ko00240	Pyrimidine metabolism	41/792	110/7206	2.98955253356e-13
ko03420	Nucleotide excision repair	25/792	46/7206	5.38737098167e-13
ko04144	Endocytosis	4/792	342/7206	5.68676773758e-13
ko05034	Alcoholism	64/792	238/7206	3.59530553673e-12
ko03430	Mismatch repair	16/792	22/7206	1.55377467619e-11
ko04020	Calcium signaling pathway	2/792	265/7206	1.97970306422e-11
ko05203	Viral carcinogenesis	69/792	277/7206	2.34658060887e-11
ko03020	RNA polymerase	18/792	29/7206	4.8843669605e-11
ko04024	cAMP signaling pathway	4/792	279/7206	5.25886858256e-10
ko03015	mRNA surveillance pathway	32/792	93/7206	1.35522703338e-09
ko04151	PI3K-Akt signaling pathway	12/792	390/7206	5.65589893347e-09
ko03018	RNA degradation	29/792	84/7206	7.41122023422e-09
ko04810	Regulation of actin cytoskeleton	5/792	264/7206	1.76531536541e-08
ko04510	Focal adhesion	4/792	240/7206	4.02182239794e-08
ko04022	cGMP-PKG signaling pathway	3/792	216/7206	5.41079115015e-08
ko04060	Cytokine-cytokine receptor interaction	2/792	191/7206	1.06109588419e-07
ko04921	Oxytocin signaling pathway	3/792	209/7206	1.19031436454e-07
ko03410	Base excision repair	17/792	38/7206	1.29710742152e-07
ko05010	Alzheimer's disease	3/792	202/7206	2.61482687162e-07
ko04724	Glutamatergic synapse	1/792	152/7206	5.7772658505e-07
ko04014	Ras signaling pathway	9/792	279/7206	2.0831439862e-06
ko04723	Retrograde endocannabinoid signaling	3/792	175/7206	3.80729979351e-06
ko04713	Circadian entrainment	1/792	136/7206	4.7117433354e-06
ko04261	Adrenergic signaling in cardiomyocytes	5/792	205/7206	6.79997494503e-06
ko04015	Rap1 signaling pathway	10/792	278/7206	8.52000851794e-06
ko00190	Oxidative phosphorylation	1/792	127/7206	9.96126849476e-06
ko04072	Phospholipase D signaling pathway	5/792	197/7206	1.38605782076e-05
ko04725	Cholinergic synapse	3/792	160/7206	1.73047378123e-05
ko04914	Progesterone-mediated oocyte maturation	27/792	104/7206	1.84954673543e-05
ko04911	Insulin secretion	1/792	117/7206	3.40808171658e-05
ko05012	Parkinson's disease	3/792	155/7206	3.84613592851e-05
ko04728	Dopaminergic synapse	5/792	185/7206	4.00774540487e-05
ko04114	Oocyte meiosis	32/792	139/7206	4.55757987872e-05
ko03450	Non-homologous end-joining	8/792	15/7206	6.52739043019e-05
ko04611	Platelet activation	4/792	163/7206	6.79195667423e-05
ko04010	MAPK signaling pathway	15/792	321/7206	7.42772409844e-05
ko04727	GABAergic synapse	1/792	110/7206	7.66533685605e-05
ko04371	Apelin signaling pathway	5/792	177/7206	8.08871332363e-05
ko04360	Axon guidance	9/792	233/7206	0.000109017400652
ko04062	Chemokine signaling pathway	7/792	201/7206	0.000138894564513
ko04621	NOD-like receptor signaling pathway	4/792	157/7206	0.000141004321972
ko05205	Proteoglycans in cancer	12/792	271/7206	0.000147385134721
ko04750	Inflammatory mediator regulation of TRP channels	2/792	122/7206	0.000183774011747
ko04530	Tight junction	9/792	228/7206	0.000212447880009
ko04971	Gastric acid secretion	1/792	98/7206	0.000245966509152
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/792	182/7206	0.000258112282742
ko04120	Ubiquitin mediated proteolysis	30/792	138/7206	0.000261932168236
ko04514	Cell adhesion molecules (CAMs)	3/792	130/7206	0.000334465761492
ko04915	Estrogen signaling pathway	3/792	131/7206	0.00033682832729
ko04070	Phosphatidylinositol signaling system	2/792	112/7206	0.000370329546273
ko05152	Tuberculosis	7/792	187/7206	0.000513275527961
ko05031	Amphetamine addiction	1/792	91/7206	0.000546547571643
ko05032	Morphine addiction	2/792	110/7206	0.000553902242793
ko04972	Pancreatic secretion	2/792	111/7206	0.000573224279884
ko04924	Renin secretion	1/792	86/7206	0.000799655449216
ko04726	Serotonergic synapse	4/792	137/7206	0.000806577036632
ko04146	Peroxisome	1/792	89/7206	0.000860435463596
ko04920	Adipocytokine signaling pathway	1/792	89/7206	0.000860435463596
ko04668	TNF signaling pathway	3/792	120/7206	0.0009978568118
ko04380	Osteoclast differentiation	4/792	134/7206	0.00114733992191
ko05231	Choline metabolism in cancer	4/792	134/7206	0.00114733992191
ko05142	Chagas disease (American trypanosomiasis)	4/792	130/7206	0.00161208455078
ko00564	Glycerophospholipid metabolism	2/792	99/7206	0.00170477813809
ko04512	ECM-receptor interaction	1/792	79/7206	0.00175646539283
ko04721	Synaptic vesicle cycle	1/792	80/7206	0.0017792682451
ko04740	Olfactory transduction	1/792	80/7206	0.0017792682451
ko05200	Pathways in cancer	34/792	492/7206	0.00212341166735
ko05169	Epstein-Barr virus infection	37/792	206/7206	0.0021663227848
ko03060	Protein export	8/792	23/7206	0.00222900082814
ko05145	Toxoplasmosis	4/792	126/7206	0.00226063468072
ko01200	Carbon metabolism	4/792	128/7206	0.00234831415644
ko04666	Fc gamma R-mediated phagocytosis	4/792	122/7206	0.00316323645987
ko04660	T cell receptor signaling pathway	4/792	124/7206	0.00327133793828
ko00230	Purine metabolism	35/792	194/7206	0.00330088991052
ko00562	Inositol phosphate metabolism	2/792	89/7206	0.00346926171164
ko05030	Cocaine addiction	1/792	73/7206	0.00391724034834
ko05166	HTLV-I infection	48/792	292/7206	0.00397056110973
ko00010	Glycolysis / Gluconeogenesis	1/792	74/7206	0.0040494999558
ko04659	Th17 cell differentiation	3/792	106/7206	0.00419114582758
ko05162	Measles	4/792	120/7206	0.00454785183527
ko04630	Jak-STAT signaling pathway	5/792	132/7206	0.00458645147718
ko04620	Toll-like receptor signaling pathway	3/792	100/7206	0.00573986195445
ko05167	Kaposi's sarcoma-associated herpesvirus infection	10/792	191/7206	0.00685550287993
ko04658	Th1 and Th2 cell differentiation	3/792	96/7206	0.00809446139957
ko04720	Long-term potentiation	3/792	99/7206	0.00849020763131
ko04066	HIF-1 signaling pathway	5/792	123/7206	0.0086382429269
ko04976	Bile secretion	2/792	80/7206	0.0105180603907
ko04933	AGE-RAGE signaling pathway in diabetic complications	6/792	135/7206	0.0116174860796
ko04912	GnRH signaling pathway	5/792	122/7206	0.0120649839626
ko00561	Glycerolipid metabolism	1/792	63/7206	0.0129276526756
ko05418	Fluid shear stress and atherosclerosis	9/792	173/7206	0.0130895120865
ko04218	Cellular senescence	30/792	177/7206	0.0144650923129
ko05140	Leishmaniasis	2/792	75/7206	0.01478954094
ko04923	Regulation of lipolysis in adipocytes	2/792	77/7206	0.0153335845197
ko04662	B cell receptor signaling pathway	3/792	88/7206	0.0159628422473
ko05323	Rheumatoid arthritis	3/792	89/7206	0.0160043527626
ko04391	Hippo signaling pathway - fly	3/792	90/7206	0.0161932707515
ko04520	Adherens junction	4/792	103/7206	0.0163654448353
ko04925	Aldosterone synthesis and secretion	4/792	105/7206	0.0168984177094
ko04962	Vasopressin-regulated water reabsorption	1/792	58/7206	0.0182581318152
ko04922	Glucagon signaling pathway	6/792	128/7206	0.0212375607934
ko04540	Gap junction	6/792	128/7206	0.0212375607934
ko05132	Salmonella infection	4/792	98/7206	0.0223936108593
ko04918	Thyroid hormone synthesis	3/792	86/7206	0.022558530775
ko05133	Pertussis	3/792	87/7206	0.0229777824892
ko04142	Lysosome	8/792	151/7206	0.0242622919923
ko04670	Leukocyte transendothelial migration	8/792	151/7206	0.0242622919923
ko04931	Insulin resistance	7/792	137/7206	0.0261599518929
ko04930	Type II diabetes mellitus	1/792	54/7206	0.026608268499
ko04152	AMPK signaling pathway	9/792	161/7206	0.0290742768641
ko04012	ErbB signaling pathway	5/792	109/7206	0.0295779782914
ko04064	NF-kappa B signaling pathway	4/792	96/7206	0.0310277038188
ko05230	Central carbon metabolism in cancer	3/792	81/7206	0.0310636972964
ko04650	Natural killer cell mediated cytotoxicity	4/792	97/7206	0.0315437422548
ko05202	Transcriptional misregulation in cancer	30/792	188/7206	0.03296980457
ko05168	Herpes simplex infection	29/792	182/7206	0.0401897662378
ko04916	Melanogenesis	8/792	142/7206	0.040930347926
ko05110	Vibrio cholerae infection	2/792	63/7206	0.0424441298739
ko00600	Sphingolipid metabolism	2/792	63/7206	0.0424441298739
ko05130	Pathogenic Escherichia coli infection	3/792	77/7206	0.0430361876188
ko04730	Long-term depression	3/792	78/7206	0.0433390846076
ko04910	Insulin signaling pathway	11/792	172/7206	0.0485965420692