ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	27/400	56/7206	8.90514574838e-20
ko04721	Synaptic vesicle cycle	28/400	80/7206	5.59123552873e-16
ko04727	GABAergic synapse	31/400	110/7206	1.44713177808e-14
ko04724	Glutamatergic synapse	36/400	152/7206	3.8064478708e-14
ko04728	Dopaminergic synapse	37/400	185/7206	4.28016164331e-12
ko05032	Morphine addiction	28/400	110/7206	4.483484304e-12
ko04723	Retrograde endocannabinoid signaling	34/400	175/7206	7.67554803028e-11
ko04080	Neuroactive ligand-receptor interaction	55/400	423/7206	1.84977649524e-09
ko04713	Circadian entrainment	26/400	136/7206	2.01398343275e-08
ko04911	Insulin secretion	22/400	117/7206	3.43740603107e-07
ko04726	Serotonergic synapse	23/400	137/7206	1.51118227992e-06
ko04725	Cholinergic synapse	24/400	160/7206	6.93806005195e-06
ko05031	Amphetamine addiction	17/400	91/7206	8.26948725851e-06
ko04024	cAMP signaling pathway	34/400	279/7206	1.20861747566e-05
ko04261	Adrenergic signaling in cardiomyocytes	27/400	205/7206	2.88500310009e-05
ko05030	Cocaine addiction	14/400	73/7206	3.82949129496e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	14/400	74/7206	4.48863271495e-05
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/400	59/7206	7.5172067451e-05
ko04360	Axon guidance	27/400	233/7206	0.000224709715631
ko04145	Phagosome	21/400	162/7206	0.000311830756328
ko04720	Long-term potentiation	15/400	99/7206	0.00033135454618
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/400	14/7206	0.000677760686363
ko04514	Cell adhesion molecules (CAMs)	17/400	130/7206	0.000796237699534
ko04964	Proximal tubule bicarbonate reclamation	7/400	29/7206	0.000828397160609
ko04010	MAPK signaling pathway	32/400	321/7206	0.00106465177491
ko04611	Platelet activation	1/400	163/7206	0.00153194619103
ko05120	Epithelial cell signaling in Helicobacter pylori infection	13/400	92/7206	0.00158513691764
ko05164	Influenza A	1/400	167/7206	0.00160211034346
ko05110	Vibrio cholerae infection	10/400	63/7206	0.00224986821841
ko04966	Collecting duct acid secretion	6/400	26/7206	0.00250927717517
ko04971	Gastric acid secretion	13/400	98/7206	0.00282192896238
ko05203	Viral carcinogenesis	5/400	277/7206	0.00292364443953
ko05166	HTLV-I infection	6/400	292/7206	0.00558370113822
ko04970	Salivary secretion	12/400	95/7206	0.00603315848151
ko04120	Ubiquitin mediated proteolysis	1/400	138/7206	0.00718179433253
ko04921	Oxytocin signaling pathway	21/400	209/7206	0.00816243074547
ko03013	RNA transport	2/400	166/7206	0.00886750543213
ko04060	Cytokine-cytokine receptor interaction	3/400	191/7206	0.0096504275994
ko05205	Proteoglycans in cancer	6/400	271/7206	0.00987617153321
ko04972	Pancreatic secretion	13/400	111/7206	0.00990423128859
ko01200	Carbon metabolism	1/400	128/7206	0.0100968047766
ko04014	Ras signaling pathway	26/400	279/7206	0.0103886116542
ko04260	Cardiac muscle contraction	12/400	98/7206	0.0112908572679
ko04621	NOD-like receptor signaling pathway	2/400	157/7206	0.0123619495704
ko05168	Herpes simplex infection	3/400	182/7206	0.0133778266821
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/400	182/7206	0.0133778266821
ko04510	Focal adhesion	5/400	240/7206	0.0138307070579
ko04668	TNF signaling pathway	1/400	120/7206	0.0145740662757
ko01522	Endocrine resistance	1/400	124/7206	0.0151959515999
ko04626	Plant-pathogen interaction	4/400	18/7206	0.0153788265409
ko04015	Rap1 signaling pathway	25/400	278/7206	0.0155154005013
ko04540	Gap junction	14/400	128/7206	0.0166056379875
ko04745	Phototransduction - fly	6/400	38/7206	0.0171719532483
ko04742	Taste transduction	8/400	61/7206	0.0186957968277
ko04978	Mineral absorption	6/400	40/7206	0.021762887966
ko04960	Aldosterone-regulated sodium reabsorption	6/400	41/7206	0.0243419679757
ko03040	Spliceosome	2/400	145/7206	0.0252920285098
ko04973	Carbohydrate digestion and absorption	6/400	42/7206	0.0271177335817
ko04940	Type I diabetes mellitus	5/400	32/7206	0.0299848074631
ko04630	Jak-STAT signaling pathway	2/400	132/7206	0.0341789774406
ko04140	Autophagy - animal	3/400	164/7206	0.0359890483553
ko04730	Long-term depression	9/400	78/7206	0.0393470472547
ko05146	Amoebiasis	1/400	99/7206	0.0440246202945
ko05169	Epstein-Barr virus infection	5/400	206/7206	0.0441443530948
ko02024	Quorum sensing	3/400	15/7206	0.0469407934439
ko04150	mTOR signaling pathway	4/400	184/7206	0.047774060275
ko04141	Protein processing in endoplasmic reticulum	4/400	184/7206	0.047774060275
ko05322	Systemic lupus erythematosus	3/400	151/7206	0.0482359199291