ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	152/1116	423/7206	1.00649024771e-26
ko04724	Glutamatergic synapse	72/1116	152/7206	7.11722965784e-21
ko05032	Morphine addiction	53/1116	110/7206	4.54922769171e-16
ko05033	Nicotine addiction	35/1116	56/7206	1.36435460782e-15
ko04727	GABAergic synapse	52/1116	110/7206	2.37725651107e-15
ko04020	Calcium signaling pathway	91/1116	265/7206	1.29621486029e-14
ko04713	Circadian entrainment	58/1116	136/7206	1.80859644277e-14
ko04728	Dopaminergic synapse	70/1116	185/7206	7.10079006818e-14
ko04024	cAMP signaling pathway	89/1116	279/7206	2.38930188724e-12
ko04911	Insulin secretion	49/1116	117/7206	4.58656104571e-12
ko04725	Cholinergic synapse	60/1116	160/7206	6.90740825873e-12
ko04723	Retrograde endocannabinoid signaling	63/1116	175/7206	1.6442044924e-11
ko04726	Serotonergic synapse	53/1116	137/7206	2.43853000572e-11
ko04921	Oxytocin signaling pathway	70/1116	209/7206	4.6542484418e-11
ko04721	Synaptic vesicle cycle	35/1116	80/7206	1.31139686908e-09
ko03010	Ribosome	1/1116	129/7206	1.10267527584e-08
ko03040	Spliceosome	2/1116	145/7206	1.6899513243e-08
ko05031	Amphetamine addiction	36/1116	91/7206	2.0050682124e-08
ko04261	Adrenergic signaling in cardiomyocytes	63/1116	205/7206	2.2573316311e-08
ko04070	Phosphatidylinositol signaling system	41/1116	112/7206	3.51154918042e-08
ko04720	Long-term potentiation	37/1116	99/7206	1.26402938941e-07
ko04744	Phototransduction	19/1116	36/7206	2.15710130032e-07
ko05322	Systemic lupus erythematosus	4/1116	151/7206	3.23449764304e-07
ko04072	Phospholipase D signaling pathway	58/1116	197/7206	6.12168966787e-07
ko04742	Taste transduction	25/1116	61/7206	1.35686022368e-06
ko05030	Cocaine addiction	28/1116	73/7206	1.57663844107e-06
ko04925	Aldosterone synthesis and secretion	36/1116	105/7206	1.68071253571e-06
ko04970	Salivary secretion	33/1116	95/7206	2.67994932892e-06
ko04110	Cell cycle	5/1116	145/7206	4.28315003691e-06
ko04022	cGMP-PKG signaling pathway	59/1116	216/7206	5.668408249e-06
ko03013	RNA transport	7/1116	166/7206	6.08831409195e-06
ko04730	Long-term depression	27/1116	78/7206	2.41939390551e-05
ko04010	MAPK signaling pathway	78/1116	321/7206	2.52366480926e-05
ko04750	Inflammatory mediator regulation of TRP channels	37/1116	122/7206	3.63402549242e-05
ko04972	Pancreatic secretion	34/1116	111/7206	5.06684978386e-05
ko03008	Ribosome biogenesis in eukaryotes	1/1116	79/7206	5.34350674083e-05
ko04971	Gastric acid secretion	31/1116	98/7206	5.44988523632e-05
ko04710	Circadian rhythm	17/1116	43/7206	0.000114673141241
ko04514	Cell adhesion molecules (CAMs)	37/1116	130/7206	0.000126589242317
ko05203	Viral carcinogenesis	22/1116	277/7206	0.000180315911733
ko04141	Protein processing in endoplasmic reticulum	12/1116	184/7206	0.000270225298025
ko05231	Choline metabolism in cancer	36/1116	134/7206	0.000635416228373
ko04960	Aldosterone-regulated sodium reabsorption	15/1116	41/7206	0.000763090615516
ko04666	Fc gamma R-mediated phagocytosis	33/1116	122/7206	0.000904080654774
ko04014	Ras signaling pathway	64/1116	279/7206	0.000929595156553
ko00562	Inositol phosphate metabolism	26/1116	89/7206	0.000953847399819
ko04930	Type II diabetes mellitus	18/1116	54/7206	0.000963444576718
ko04745	Phototransduction - fly	14/1116	38/7206	0.00104945029822
ko04350	TGF-beta signaling pathway	5/1116	103/7206	0.00137264670051
ko03050	Proteasome	1/1116	54/7206	0.00205285216534
ko00520	Amino sugar and nucleotide sugar metabolism	1/1116	55/7206	0.00211819576774
ko05133	Pertussis	4/1116	87/7206	0.00253267999015
ko04966	Collecting duct acid secretion	10/1116	26/7206	0.00376704892127
ko04650	Natural killer cell mediated cytotoxicity	26/1116	97/7206	0.00417506271407
ko04922	Glucagon signaling pathway	32/1116	128/7206	0.00436969477927
ko00240	Pyrimidine metabolism	7/1116	110/7206	0.00503566948974
ko05014	Amyotrophic lateral sclerosis (ALS)	21/1116	74/7206	0.00517155854297
ko04924	Renin secretion	23/1116	86/7206	0.00642840419666
ko04923	Regulation of lipolysis in adipocytes	21/1116	77/7206	0.00672739330326
ko03420	Nucleotide excision repair	1/1116	46/7206	0.00690660192441
ko04915	Estrogen signaling pathway	32/1116	131/7206	0.00693322675017
ko05110	Vibrio cholerae infection	18/1116	63/7206	0.00765551443111
ko04711	Circadian rhythm - fly	6/1116	13/7206	0.00876955943021
ko04540	Gap junction	31/1116	128/7206	0.00914252848752
ko04973	Carbohydrate digestion and absorption	13/1116	42/7206	0.00959250970319
ko04360	Axon guidance	51/1116	233/7206	0.00961475962255
ko05130	Pathogenic Escherichia coli infection	4/1116	77/7206	0.0102198004861
ko03022	Basal transcription factors	1/1116	44/7206	0.0104745729921
ko04260	Cardiac muscle contraction	25/1116	98/7206	0.0104956345006
ko04071	Sphingolipid signaling pathway	37/1116	162/7206	0.0114321819453
ko04120	Ubiquitin mediated proteolysis	11/1116	138/7206	0.0121017103244
ko05230	Central carbon metabolism in cancer	21/1116	81/7206	0.0130112068225
ko00965	Betalain biosynthesis	3/1116	4/7206	0.0131065680451
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1116	14/7206	0.0133660441778
ko04062	Chemokine signaling pathway	44/1116	201/7206	0.0133796309293
ko04919	Thyroid hormone signaling pathway	33/1116	143/7206	0.0141643044931
ko05016	Huntington's disease	21/1116	215/7206	0.0165792274405
ko04662	B cell receptor signaling pathway	22/1116	88/7206	0.0173798685863
ko04270	Vascular smooth muscle contraction	35/1116	154/7206	0.0174095171153
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/1116	59/7206	0.018355562021
ko05169	Epstein-Barr virus infection	20/1116	206/7206	0.018730775408
ko05168	Herpes simplex infection	17/1116	182/7206	0.0217857688396
ko03410	Base excision repair	1/1116	38/7206	0.0229122960675
ko00120	Primary bile acid biosynthesis	7/1116	20/7206	0.0256207006345
ko04215	Apoptosis - multiple species	2/1116	47/7206	0.0262079056612
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	20/1116	79/7206	0.0268381879283
ko05217	Basal cell carcinoma	4/1116	68/7206	0.0271038596512
ko05414	Dilated cardiomyopathy	26/1116	112/7206	0.0338752645435
ko04918	Thyroid hormone synthesis	21/1116	86/7206	0.0340399588225
ko05145	Toxoplasmosis	11/1116	126/7206	0.034125721347
ko04964	Proximal tubule bicarbonate reclamation	9/1116	29/7206	0.0342874984725
ko04371	Apelin signaling pathway	38/1116	177/7206	0.0346029530047
ko00564	Glycerophospholipid metabolism	23/1116	99/7206	0.0361687929632
ko04550	Signaling pathways regulating pluripotency of stem cells	16/1116	165/7206	0.038142020478
ko05200	Pathways in cancer	60/1116	492/7206	0.0386296163715
ko05214	Glioma	19/1116	79/7206	0.0414260522377
ko05131	Shigellosis	6/1116	82/7206	0.0443135212795
ko04626	Plant-pathogen interaction	6/1116	18/7206	0.0478172658216
ko04214	Apoptosis - fly	5/1116	72/7206	0.0478705878909