ko pathway ratio_in_study ratio_in_pop p_value ko04110 Cell cycle 39/244 145/7206 3.42837041634e-25 ko04111 Cell cycle - yeast 31/244 90/7206 8.89266946872e-24 ko03040 Spliceosome 30/244 145/7206 4.51133571652e-16 ko04113 Meiosis - yeast 21/244 70/7206 4.97157704354e-15 ko03030 DNA replication 16/244 38/7206 2.0973714033e-14 ko03410 Base excision repair 11/244 38/7206 2.87147251295e-08 ko03013 RNA transport 18/244 166/7206 1.14018307698e-05 ko00240 Pyrimidine metabolism 14/244 110/7206 1.81354398561e-05 ko05206 MicroRNAs in cancer 18/244 177/7206 2.7563646857e-05 ko05166 HTLV-I infection 24/244 292/7206 4.65659252891e-05 ko03430 Mismatch repair 6/244 22/7206 6.69935928599e-05 ko04114 Oocyte meiosis 14/244 139/7206 0.000241188099397 ko04550 Signaling pathways regulating pluripotency of stem cells 15/244 165/7206 0.000446622625986 ko04020 Calcium signaling pathway 1/244 265/7206 0.00159344735596 ko03018 RNA degradation 9/244 84/7206 0.00202838880614 ko03440 Homologous recombination 6/244 41/7206 0.00235573266414 ko04914 Progesterone-mediated oocyte maturation 10/244 104/7206 0.00262994209009 ko03015 mRNA surveillance pathway 9/244 93/7206 0.00407377785954 ko03420 Nucleotide excision repair 6/244 46/7206 0.00426328276637 ko04330 Notch signaling pathway 7/244 62/7206 0.00470608186777 ko04144 Endocytosis 3/244 342/7206 0.00512041517328 ko05168 Herpes simplex infection 14/244 182/7206 0.00514439407764 ko04024 cAMP signaling pathway 2/244 279/7206 0.0062723421858 ko04120 Ubiquitin mediated proteolysis 11/244 138/7206 0.00696144027514 ko03460 Fanconi anemia pathway 6/244 51/7206 0.00712436597564 ko05217 Basal cell carcinoma 7/244 68/7206 0.0078190113618 ko05203 Viral carcinogenesis 18/244 277/7206 0.00955196541466 ko05222 Small cell lung cancer 8/244 89/7206 0.010244717659 ko04022 cGMP-PKG signaling pathway 1/244 216/7206 0.0110227038183 ko05215 Prostate cancer 9/244 111/7206 0.0126788248293 ko05322 Systemic lupus erythematosus 11/244 151/7206 0.0184577138658 ko04218 Cellular senescence 12/244 177/7206 0.0188541751423 ko05200 Pathways in cancer 26/244 492/7206 0.0200070036807 ko00270 Cysteine and methionine metabolism 5/244 47/7206 0.0205832659789 ko04310 Wnt signaling pathway 12/244 181/7206 0.0214664165536 ko05152 Tuberculosis 1/244 187/7206 0.0220519362576 ko05219 Bladder cancer 5/244 48/7206 0.0223626748952 ko05220 Chronic myeloid leukemia 7/244 85/7206 0.024604660704 ko04530 Tight junction 2/244 228/7206 0.0250540649697 ko04371 Apelin signaling pathway 1/244 177/7206 0.0321076403956 ko05202 Transcriptional misregulation in cancer 12/244 188/7206 0.0365504514571 ko00310 Lysine degradation 6/244 73/7206 0.0365509081707 ko04151 PI3K-Akt signaling pathway 6/244 390/7206 0.0419868748104 ko04725 Cholinergic synapse 1/244 160/7206 0.0452146923493 ko04611 Platelet activation 1/244 163/7206 0.0455984557834 ko04261 Adrenergic signaling in cardiomyocytes 2/244 205/7206 0.0490862858357 ko04921 Oxytocin signaling pathway 2/244 209/7206 0.0495529323434