ko pathway ratio_in_study ratio_in_pop p_value ko05200 Pathways in cancer 49/197 492/7206 4.2639049081e-16 ko04390 Hippo signaling pathway 28/197 188/7206 1.09421965809e-13 ko05217 Basal cell carcinoma 17/197 68/7206 1.76499476358e-12 ko04360 Axon guidance 27/197 233/7206 1.30529279828e-10 ko05224 Breast cancer 22/197 174/7206 1.46974796448e-09 ko04550 Signaling pathways regulating pluripotency of stem cells 20/197 165/7206 1.79203804249e-08 ko04916 Melanogenesis 17/197 142/7206 2.66996913879e-07 ko05205 Proteoglycans in cancer 24/197 271/7206 2.95226692708e-07 ko04391 Hippo signaling pathway - fly 13/197 90/7206 8.29951975504e-07 ko05222 Small cell lung cancer 12/197 89/7206 4.67521537381e-06 ko04151 PI3K-Akt signaling pathway 27/197 390/7206 6.57031207476e-06 ko04310 Wnt signaling pathway 17/197 181/7206 8.06889481444e-06 ko04340 Hedgehog signaling pathway 9/197 58/7206 2.37281543224e-05 ko04512 ECM-receptor interaction 10/197 79/7206 5.176543204e-05 ko04392 Hippo signaling pathway -multiple species 6/197 31/7206 0.000160928325383 ko04350 TGF-beta signaling pathway 10/197 103/7206 0.000480031609339 ko01522 Endocrine resistance 11/197 124/7206 0.000549687461056 ko04015 Rap1 signaling pathway 18/197 278/7206 0.000566772391541 ko04658 Th1 and Th2 cell differentiation 9/197 96/7206 0.0011811309716 ko05166 HTLV-I infection 18/197 292/7206 0.00126445643001 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 8/197 79/7206 0.00133939870378 ko04330 Notch signaling pathway 7/197 62/7206 0.00141221026261 ko05219 Bladder cancer 6/197 48/7206 0.00182375105552 ko05212 Pancreatic cancer 8/197 83/7206 0.00184537193683 ko04514 Cell adhesion molecules (CAMs) 10/197 130/7206 0.00286702555076 ko04011 MAPK signaling pathway - yeast 6/197 53/7206 0.00304772432158 ko05206 MicroRNAs in cancer 12/197 177/7206 0.00325135871538 ko04341 Hedgehog signaling pathway - fly 5/197 38/7206 0.00349801038014 ko04933 AGE-RAGE signaling pathway in diabetic complications 10/197 135/7206 0.00376805635804 ko04080 Neuroactive ligand-receptor interaction 3/197 423/7206 0.00499054050758 ko05146 Amoebiasis 8/197 99/7206 0.00553008806555 ko04919 Thyroid hormone signaling pathway 10/197 143/7206 0.00566282242385 ko04060 Cytokine-cytokine receptor interaction 12/197 191/7206 0.00598314351828 ko04510 Focal adhesion 14/197 240/7206 0.00708703285093 ko04670 Leukocyte transendothelial migration 10/197 151/7206 0.00823305875075 ko05220 Chronic myeloid leukemia 7/197 85/7206 0.0083755101497 ko00514 Other types of O-glycan biosynthesis 4/197 30/7206 0.00850846405986 ko05215 Prostate cancer 8/197 111/7206 0.010816155295 ko04530 Tight junction 13/197 228/7206 0.0111238046186 ko04722 Neurotrophin signaling pathway 10/197 160/7206 0.0121097684618 ko00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 3/197 19/7206 0.0141179394836 ko04668 TNF signaling pathway 8/197 120/7206 0.0167410269157 ko04150 mTOR signaling pathway 11/197 184/7206 0.0175956005413 ko04810 Regulation of actin cytoskeleton 14/197 264/7206 0.0182173129617 ko04962 Vasopressin-regulated water reabsorption 5/197 58/7206 0.0206128601618 ko05145 Toxoplasmosis 8/197 126/7206 0.021810429591 ko04961 Endocrine and other factor-regulated calcium reabsorption 5/197 59/7206 0.0220375789377 ko04520 Adherens junction 7/197 103/7206 0.0223542249075 ko04014 Ras signaling pathway 14/197 279/7206 0.02383568813 ko05131 Shigellosis 6/197 82/7206 0.0242972887101 ko05142 Chagas disease (American trypanosomiasis) 8/197 130/7206 0.02574184252 ko00944 Flavone and flavonol biosynthesis 1/197 1/7206 0.0273383291702 ko05221 Acute myeloid leukemia 5/197 63/7206 0.0283703756109 ko01523 Antifolate resistance 3/197 30/7206 0.0475606357454