ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	58/355	423/7206	3.44490378663e-13
ko05033	Nicotine addiction	20/355	56/7206	6.45992925711e-13
ko04724	Glutamatergic synapse	29/355	152/7206	1.87992627366e-10
ko04727	GABAergic synapse	24/355	110/7206	4.18912340976e-10
ko04723	Retrograde endocannabinoid signaling	28/355	175/7206	2.40809424581e-08
ko04728	Dopaminergic synapse	28/355	185/7206	8.25473675317e-08
ko05032	Morphine addiction	20/355	110/7206	3.10564734095e-07
ko04713	Circadian entrainment	22/355	136/7206	6.5945105138e-07
ko04974	Protein digestion and absorption	18/355	96/7206	7.62755901333e-07
ko04721	Synaptic vesicle cycle	16/355	80/7206	1.28788632639e-06
ko05030	Cocaine addiction	15/355	73/7206	1.93684198343e-06
ko04978	Mineral absorption	11/355	40/7206	2.26184847856e-06
ko04976	Bile secretion	14/355	80/7206	2.97713769691e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	13/355	74/7206	5.49162124815e-05
ko04744	Phototransduction	8/355	36/7206	0.000287903698843
ko04725	Cholinergic synapse	19/355	160/7206	0.000306605834498
ko04726	Serotonergic synapse	17/355	137/7206	0.000376260681006
ko04730	Long-term depression	12/355	78/7206	0.000387661756681
ko04964	Proximal tubule bicarbonate reclamation	7/355	29/7206	0.000403932036002
ko05031	Amphetamine addiction	13/355	91/7206	0.000471105351577
ko04514	Cell adhesion molecules (CAMs)	16/355	130/7206	0.000609545148978
ko04911	Insulin secretion	14/355	117/7206	0.00173482993868
ko04740	Olfactory transduction	11/355	80/7206	0.00174593503424
ko05166	HTLV-I infection	4/355	292/7206	0.00205676414011
ko04970	Salivary secretion	12/355	95/7206	0.00229918384509
ko04217	Necroptosis	1/355	178/7206	0.00231856463744
ko04742	Taste transduction	9/355	61/7206	0.00276054302959
ko05169	Epstein-Barr virus infection	2/355	206/7206	0.00304174532343
ko04924	Renin secretion	11/355	86/7206	0.00313275428936
ko05164	Influenza A	1/355	167/7206	0.0033212008666
ko05161	Hepatitis B	1/355	173/7206	0.00353377418317
ko05203	Viral carcinogenesis	4/355	277/7206	0.00405028242732
ko04024	cAMP signaling pathway	25/355	279/7206	0.00416607627497
ko04512	ECM-receptor interaction	10/355	79/7206	0.00513501041445
ko04110	Cell cycle	1/355	145/7206	0.0103121446754
ko04972	Pancreatic secretion	12/355	111/7206	0.011715466036
ko05206	MicroRNAs in cancer	2/355	177/7206	0.0125342287765
ko04550	Signaling pathways regulating pluripotency of stem cells	2/355	165/7206	0.0175077255284
ko00350	Tyrosine metabolism	5/355	33/7206	0.0214673842409
ko00680	Methane metabolism	5/355	34/7206	0.0241847147611
ko04621	NOD-like receptor signaling pathway	2/355	157/7206	0.0246341199059
ko04060	Cytokine-cytokine receptor interaction	3/355	191/7206	0.026050743928
ko00410	beta-Alanine metabolism	5/355	35/7206	0.027114066776
ko00730	Thiamine metabolism	3/355	14/7206	0.0287799190898
ko00770	Pantothenate and CoA biosynthesis	3/355	14/7206	0.0287799190898
ko00430	Taurine and hypotaurine metabolism	3/355	14/7206	0.0287799190898
ko04971	Gastric acid secretion	10/355	98/7206	0.0287984568905
ko04720	Long-term potentiation	10/355	99/7206	0.0298971299353
ko04668	TNF signaling pathway	1/355	120/7206	0.0309949766864
ko04211	Longevity regulating pathway	1/355	123/7206	0.0318956743708
ko04261	Adrenergic signaling in cardiomyocytes	17/355	205/7206	0.0319014363593
ko04660	T cell receptor signaling pathway	1/355	124/7206	0.0323411818938
ko05034	Alcoholism	19/355	238/7206	0.0326040782725
ko05322	Systemic lupus erythematosus	2/355	151/7206	0.0347299622827
ko04210	Apoptosis	3/355	180/7206	0.0355523834463
ko04141	Protein processing in endoplasmic reticulum	3/355	184/7206	0.0361140199381
ko00710	Carbon fixation in photosynthetic organisms	4/355	27/7206	0.0414645810832
ko04012	ErbB signaling pathway	1/355	109/7206	0.044233215789
ko02025	Biofilm formation - Pseudomonas aeruginosa	1/355	1/7206	0.0492645018042
ko04218	Cellular senescence	3/355	177/7206	0.0499764257105