ko pathway ratio_in_study ratio_in_pop p_value ko04976 Bile secretion 24/388 80/7206 1.75437803161e-12 ko04974 Protein digestion and absorption 23/388 96/7206 7.78773662319e-10 ko04080 Neuroactive ligand-receptor interaction 48/388 423/7206 5.87102554661e-07 ko04610 Complement and coagulation cascades 17/388 79/7206 6.95487419188e-07 ko00983 Drug metabolism - other enzymes 12/388 42/7206 1.271445837e-06 ko00380 Tryptophan metabolism 13/388 50/7206 1.50030134506e-06 ko04972 Pancreatic secretion 19/388 111/7206 5.99174254031e-06 ko04977 Vitamin digestion and absorption 8/388 22/7206 1.07856585008e-05 ko04742 Taste transduction 13/388 61/7206 1.61482146394e-05 ko04614 Renin-angiotensin system 7/388 18/7206 2.35834828214e-05 ko02010 ABC transporters 10/388 39/7206 2.83892588287e-05 ko00260 Glycine, serine and threonine metabolism 11/388 48/7206 3.5523058988e-05 ko04978 Mineral absorption 10/388 40/7206 3.60625235481e-05 ko04975 Fat digestion and absorption 9/388 35/7206 7.00303501076e-05 ko05166 HTLV-I infection 3/388 292/7206 0.000156537601935 ko00360 Phenylalanine metabolism 6/388 17/7206 0.000174629905869 ko00340 Histidine metabolism 7/388 25/7206 0.000256459926078 ko00350 Tyrosine metabolism 8/388 33/7206 0.000277548952624 ko05203 Viral carcinogenesis 3/388 277/7206 0.000320637635842 ko04924 Renin secretion 13/388 86/7206 0.000628196335969 ko04310 Wnt signaling pathway 1/388 181/7206 0.000718587783458 ko04141 Protein processing in endoplasmic reticulum 1/388 184/7206 0.000723780085756 ko05016 Huntington's disease 2/388 215/7206 0.00103486982366 ko00140 Steroid hormone biosynthesis 8/388 41/7206 0.0013086609903 ko00950 Isoquinoline alkaloid biosynthesis 4/388 10/7206 0.00134066029526 ko00232 Caffeine metabolism 3/388 5/7206 0.00142803838396 ko05169 Epstein-Barr virus infection 2/388 206/7206 0.00147107807331 ko00830 Retinol metabolism 8/388 42/7206 0.00154217857043 ko05200 Pathways in cancer 12/388 492/7206 0.00174599612313 ko03013 RNA transport 1/388 166/7206 0.00240980322728 ko04744 Phototransduction 7/388 36/7206 0.00266742963426 ko00982 Drug metabolism - cytochrome P450 7/388 37/7206 0.00314080645564 ko05012 Parkinson's disease 1/388 155/7206 0.00332001708631 ko00120 Primary bile acid biosynthesis 5/388 20/7206 0.00349012555148 ko04740 Olfactory transduction 11/388 80/7206 0.00349837121486 ko03320 PPAR signaling pathway 10/388 69/7206 0.00358433985957 ko00250 Alanine, aspartate and glutamate metabolism 7/388 38/7206 0.00367577749556 ko05204 Chemical carcinogenesis 8/388 48/7206 0.00371896381118 ko04932 Non-alcoholic fatty liver disease (NAFLD) 2/388 182/7206 0.00428951667907 ko04110 Cell cycle 1/388 145/7206 0.00477316924322 ko04020 Calcium signaling pathway 25/388 265/7206 0.00527207548264 ko00770 Pantothenate and CoA biosynthesis 4/388 14/7206 0.00538090017063 ko00591 Linoleic acid metabolism 5/388 22/7206 0.00542439044912 ko04270 Vascular smooth muscle contraction 17/388 154/7206 0.00547343141345 ko04971 Gastric acid secretion 12/388 98/7206 0.00610048676282 ko04144 Endocytosis 8/388 342/7206 0.00677789505906 ko04120 Ubiquitin mediated proteolysis 1/388 138/7206 0.00694455075026 ko04151 PI3K-Akt signaling pathway 10/388 390/7206 0.00779016208951 ko04146 Peroxisome 11/388 89/7206 0.00791754975657 ko05031 Amphetamine addiction 11/388 91/7206 0.0093239486023 ko00230 Purine metabolism 19/388 194/7206 0.00956159232035 ko04933 AGE-RAGE signaling pathway in diabetic complications 1/388 135/7206 0.0104930754034 ko04722 Neurotrophin signaling pathway 2/388 160/7206 0.0122986709316 ko05205 Proteoglycans in cancer 6/388 271/7206 0.0132701522361 ko05152 Tuberculosis 3/388 187/7206 0.0134249273176 ko00965 Betalain biosynthesis 2/388 4/7206 0.0161377898414 ko04142 Lysosome 2/388 151/7206 0.0173518203939 ko04970 Salivary secretion 11/388 95/7206 0.0177317181248 ko04964 Proximal tubule bicarbonate reclamation 5/388 29/7206 0.0179652997233 ko04950 Maturity onset diabetes of the young 5/388 29/7206 0.0179652997233 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 3/388 11/7206 0.0184905707056 ko04150 mTOR signaling pathway 3/388 184/7206 0.0189352217137 ko04913 Ovarian steroidogenesis 8/388 63/7206 0.0189711522065 ko04726 Serotonergic synapse 14/388 137/7206 0.0195167213965 ko04973 Carbohydrate digestion and absorption 6/388 42/7206 0.023758971382 ko00100 Steroid biosynthesis 4/388 21/7206 0.0238910717795 ko04919 Thyroid hormone signaling pathway 2/388 143/7206 0.0244416518495 ko05161 Hepatitis B 3/388 173/7206 0.0256977060916 ko05224 Breast cancer 3/388 174/7206 0.0257742511651 ko04218 Cellular senescence 3/388 177/7206 0.0262988205211 ko00053 Ascorbate and aldarate metabolism 4/388 22/7206 0.027994778742 ko04010 MAPK signaling pathway 9/388 321/7206 0.0315148804442 ko00680 Methane metabolism 5/388 34/7206 0.0338371182635 ko00362 Benzoate degradation 2/388 6/7206 0.0375453365221 ko00410 beta-Alanine metabolism 5/388 35/7206 0.037798023389 ko04750 Inflammatory mediator regulation of TRP channels 12/388 122/7206 0.0397329501237 ko04724 Glutamatergic synapse 14/388 152/7206 0.0438904277735 ko04520 Adherens junction 1/388 103/7206 0.044463840456 ko01230 Biosynthesis of amino acids 9/388 85/7206 0.0471892890248 ko04630 Jak-STAT signaling pathway 2/388 132/7206 0.0486405804176 ko04380 Osteoclast differentiation 2/388 134/7206 0.0495757137815