ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 38/283 79/7206 3.91050809576e-33 ko04975 Fat digestion and absorption 15/283 35/7206 9.04692032589e-13 ko04974 Protein digestion and absorption 20/283 96/7206 5.7105893199e-10 ko00983 Drug metabolism - other enzymes 12/283 42/7206 4.10796037021e-08 ko04977 Vitamin digestion and absorption 9/283 22/7206 6.2138765328e-08 ko05150 Staphylococcus aureus infection 11/283 36/7206 7.06805970371e-08 ko04978 Mineral absorption 11/283 40/7206 2.36310113985e-07 ko04976 Bile secretion 14/283 80/7206 2.20004401262e-06 ko04614 Renin-angiotensin system 7/283 18/7206 2.93457416462e-06 ko03320 PPAR signaling pathway 12/283 69/7206 1.26529023685e-05 ko05204 Chemical carcinogenesis 9/283 48/7206 8.51521369741e-05 ko00260 Glycine, serine and threonine metabolism 9/283 48/7206 8.51521369741e-05 ko00630 Glyoxylate and dicarboxylate metabolism 8/283 38/7206 8.96462013458e-05 ko04964 Proximal tubule bicarbonate reclamation 7/283 29/7206 9.91599641536e-05 ko04950 Maturity onset diabetes of the young 7/283 29/7206 9.91599641536e-05 ko04972 Pancreatic secretion 14/283 111/7206 0.000102539906335 ko00380 Tryptophan metabolism 9/283 50/7206 0.000118732844868 ko01200 Carbon metabolism 15/283 128/7206 0.000135925597385 ko05166 HTLV-I infection 1/283 292/7206 0.000159221269771 ko04973 Carbohydrate digestion and absorption 8/283 42/7206 0.000188736773386 ko05200 Pathways in cancer 6/283 492/7206 0.000428689131407 ko00232 Caffeine metabolism 3/283 5/7206 0.000565151414034 ko00980 Metabolism of xenobiotics by cytochrome P450 7/283 40/7206 0.000817817601755 ko00140 Steroid hormone biosynthesis 7/283 41/7206 0.000953643533334 ko00100 Steroid biosynthesis 5/283 21/7206 0.00109257184049 ko00830 Retinol metabolism 7/283 42/7206 0.00110662488531 ko00591 Linoleic acid metabolism 5/283 22/7206 0.00136907222795 ko04360 Axon guidance 1/283 233/7206 0.00161467122928 ko05133 Pertussis 10/283 87/7206 0.00205167768782 ko00040 Pentose and glucuronate interconversions 5/283 26/7206 0.00300712389356 ko05016 Huntington's disease 1/283 215/7206 0.00351153485573 ko02010 ABC transporters 6/283 39/7206 0.00380456609184 ko04144 Endocytosis 4/283 342/7206 0.00390509347241 ko04080 Neuroactive ligand-receptor interaction 6/283 423/7206 0.00409018549402 ko04922 Glucagon signaling pathway 12/283 128/7206 0.00433199022323 ko04152 AMPK signaling pathway 14/283 161/7206 0.00570895085085 ko01230 Biosynthesis of amino acids 9/283 85/7206 0.00588598052011 ko05034 Alcoholism 2/283 238/7206 0.00626142625438 ko00120 Primary bile acid biosynthesis 4/283 20/7206 0.00685688995394 ko04216 Ferroptosis 6/283 44/7206 0.00698923472524 ko04010 MAPK signaling pathway 4/283 321/7206 0.00747464547686 ko04920 Adipocytokine signaling pathway 9/283 89/7206 0.00793240493205 ko00643 Styrene degradation 2/283 4/7206 0.00875004601277 ko00270 Cysteine and methionine metabolism 6/283 47/7206 0.00964042935977 ko00053 Ascorbate and aldarate metabolism 4/283 22/7206 0.00973411740264 ko04217 Necroptosis 1/283 178/7206 0.0103835836627 ko04141 Protein processing in endoplasmic reticulum 1/283 184/7206 0.0106905599205 ko00982 Drug metabolism - cytochrome P450 5/283 37/7206 0.0140291369852 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/283 5/7206 0.0142066424121 ko00340 Histidine metabolism 4/283 25/7206 0.0153529246014 ko00590 Arachidonic acid metabolism 6/283 52/7206 0.0155365991293 ko00250 Alanine, aspartate and glutamate metabolism 5/283 38/7206 0.0156507345634 ko00770 Pantothenate and CoA biosynthesis 3/283 14/7206 0.0158117552194 ko05020 Prion diseases 5/283 40/7206 0.0192587008491 ko00710 Carbon fixation in photosynthetic organisms 4/283 27/7206 0.0200364913454 ko00480 Glutathione metabolism 6/283 55/7206 0.0200749085217 ko04621 NOD-like receptor signaling pathway 1/283 157/7206 0.0217002623066 ko04931 Insulin resistance 11/283 137/7206 0.0225393675842 ko03013 RNA transport 1/283 166/7206 0.0229026537423 ko04146 Peroxisome 8/283 89/7206 0.0231339811521 ko04062 Chemokine signaling pathway 2/283 201/7206 0.0252098418212 ko00010 Glycolysis / Gluconeogenesis 7/283 74/7206 0.0255207708677 ko05169 Epstein-Barr virus infection 2/283 206/7206 0.0261875833739 ko00061 Fatty acid biosynthesis 3/283 17/7206 0.0270871269881 ko00360 Phenylalanine metabolism 3/283 17/7206 0.0270871269881 ko00330 Arginine and proline metabolism 6/283 61/7206 0.0316846735422 ko00620 Pyruvate metabolism 5/283 46/7206 0.0332107567213 ko04913 Ovarian steroidogenesis 6/283 63/7206 0.0363585546525 ko00910 Nitrogen metabolism 3/283 19/7206 0.0364443113563 ko00350 Tyrosine metabolism 4/283 33/7206 0.0389311493052 ko00401 Novobiocin biosynthesis 1/283 1/7206 0.0392728281988 ko00670 One carbon pool by folate 3/283 20/7206 0.0416656210153 ko00680 Methane metabolism 4/283 34/7206 0.0428085014277 ko00640 Propanoate metabolism 4/283 34/7206 0.0428085014277 ko00860 Porphyrin and chlorophyll metabolism 4/283 34/7206 0.0428085014277 ko00410 beta-Alanine metabolism 4/283 35/7206 0.046895650367 ko00500 Starch and sucrose metabolism 4/283 35/7206 0.046895650367 ko04110 Cell cycle 1/283 145/7206 0.0469952840017 ko05206 MicroRNAs in cancer 2/283 177/7206 0.0489220871423