ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	74/524	145/7206	1.09298159203e-46
ko04110	Cell cycle	48/524	145/7206	2.74371990039e-20
ko05322	Systemic lupus erythematosus	49/524	151/7206	2.87144901865e-20
ko04111	Cell cycle - yeast	36/524	90/7206	1.4135751166e-18
ko03013	RNA transport	49/524	166/7206	2.61515409454e-18
ko03030	DNA replication	23/524	38/7206	2.28558543221e-17
ko03440	Homologous recombination	21/524	41/7206	5.75481544917e-14
ko05034	Alcoholism	52/524	238/7206	2.21669239529e-13
ko03008	Ribosome biogenesis in eukaryotes	28/524	79/7206	3.76354919032e-13
ko04113	Meiosis - yeast	25/524	70/7206	5.81176088087e-12
ko03460	Fanconi anemia pathway	20/524	51/7206	1.10687307948e-10
ko04144	Endocytosis	1/524	342/7206	1.54661738899e-10
ko03410	Base excision repair	17/524	38/7206	2.3617562359e-10
ko00240	Pyrimidine metabolism	29/524	110/7206	5.35523185128e-10
ko03430	Mismatch repair	12/524	22/7206	6.37501596897e-09
ko03018	RNA degradation	23/524	84/7206	1.54964325014e-08
ko03420	Nucleotide excision repair	16/524	46/7206	6.23093676749e-08
ko05203	Viral carcinogenesis	46/524	277/7206	8.38004304128e-08
ko04024	cAMP signaling pathway	3/524	279/7206	1.65387058719e-06
ko04151	PI3K-Akt signaling pathway	8/524	390/7206	4.73864378669e-06
ko03022	Basal transcription factors	13/524	44/7206	8.73257931381e-06
ko04060	Cytokine-cytokine receptor interaction	1/524	191/7206	1.34823171776e-05
ko05152	Tuberculosis	1/524	187/7206	2.05305832433e-05
ko04022	cGMP-PKG signaling pathway	2/524	216/7206	2.36933475751e-05
ko04261	Adrenergic signaling in cardiomyocytes	2/524	205/7206	5.05600364014e-05
ko03015	mRNA surveillance pathway	18/524	93/7206	0.000103258105522
ko04510	Focal adhesion	4/524	240/7206	0.000121769467241
ko04728	Dopaminergic synapse	2/524	185/7206	0.000150050832545
ko04114	Oocyte meiosis	23/524	139/7206	0.000176396883023
ko04921	Oxytocin signaling pathway	3/524	209/7206	0.000203377304602
ko04142	Lysosome	1/524	151/7206	0.000207727697213
ko04724	Glutamatergic synapse	1/524	152/7206	0.000208011720762
ko05202	Transcriptional misregulation in cancer	28/524	188/7206	0.000271788434259
ko04723	Retrograde endocannabinoid signaling	2/524	175/7206	0.000316974091039
ko04072	Phospholipase D signaling pathway	3/524	197/7206	0.00041271689596
ko04914	Progesterone-mediated oocyte maturation	18/524	104/7206	0.00044447049783
ko05166	HTLV-I infection	38/524	292/7206	0.000469025715334
ko04810	Regulation of actin cytoskeleton	6/524	264/7206	0.000607146455871
ko04713	Circadian entrainment	1/524	136/7206	0.000665831812806
ko03020	RNA polymerase	8/524	29/7206	0.000810138463121
ko04141	Protein processing in endoplasmic reticulum	3/524	184/7206	0.000833868336505
ko04621	NOD-like receptor signaling pathway	2/524	157/7206	0.000952348401059
ko05205	Proteoglycans in cancer	7/524	271/7206	0.0011406205478
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/524	182/7206	0.0012132275285
ko04120	Ubiquitin mediated proteolysis	21/524	138/7206	0.00124104401945
ko05012	Parkinson's disease	2/524	155/7206	0.00141696636649
ko04010	MAPK signaling pathway	10/524	321/7206	0.00191679716715
ko04015	Rap1 signaling pathway	8/524	278/7206	0.00205631562902
ko04014	Ras signaling pathway	8/524	279/7206	0.00206082233406
ko04668	TNF signaling pathway	1/524	120/7206	0.00211223226491
ko04750	Inflammatory mediator regulation of TRP channels	1/524	122/7206	0.00218569416905
ko04911	Insulin secretion	1/524	117/7206	0.00323604487439
ko04145	Phagosome	3/524	162/7206	0.00333861539698
ko04611	Platelet activation	3/524	163/7206	0.00334942592092
ko04530	Tight junction	6/524	228/7206	0.00393662696277
ko04931	Insulin resistance	2/524	137/7206	0.00409687619027
ko04727	GABAergic synapse	1/524	110/7206	0.00457884318877
ko04725	Cholinergic synapse	3/524	160/7206	0.00485396663399
ko04152	AMPK signaling pathway	3/524	161/7206	0.00494736073046
ko04371	Apelin signaling pathway	4/524	177/7206	0.00507120344911
ko05142	Chagas disease (American trypanosomiasis)	2/524	130/7206	0.00578532162762
ko04514	Cell adhesion molecules (CAMs)	2/524	130/7206	0.00578532162762
ko05145	Toxoplasmosis	2/524	126/7206	0.00835358976987
ko01200	Carbon metabolism	2/524	128/7206	0.00864069630408
ko04971	Gastric acid secretion	1/524	98/7206	0.00961081148101
ko04140	Autophagy - animal	4/524	164/7206	0.013667884112
ko00230	Purine metabolism	23/524	194/7206	0.0169840446907
ko04380	Osteoclast differentiation	3/524	134/7206	0.0178496870465
ko05231	Choline metabolism in cancer	3/524	134/7206	0.0178496870465
ko04726	Serotonergic synapse	3/524	137/7206	0.018327898639
ko04360	Axon guidance	8/524	233/7206	0.0200840892133
ko04924	Renin secretion	1/524	86/7206	0.0201662662617
ko05323	Rheumatoid arthritis	1/524	89/7206	0.0209558140769
ko05167	Kaposi's sarcoma-associated herpesvirus infection	6/524	191/7206	0.0229339689259
ko04659	Th17 cell differentiation	2/524	106/7206	0.0234124935545
ko05032	Morphine addiction	2/524	110/7206	0.0240437762503
ko04972	Pancreatic secretion	2/524	111/7206	0.0244559452466
ko04915	Estrogen signaling pathway	3/524	131/7206	0.0252696336894
ko04630	Jak-STAT signaling pathway	3/524	132/7206	0.0256379362508
ko04217	Necroptosis	21/524	178/7206	0.0269004413562
ko04740	Olfactory transduction	1/524	80/7206	0.0291831439845
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	1/524	79/7206	0.029194274689
ko04512	ECM-receptor interaction	1/524	79/7206	0.029194274689
ko04071	Sphingolipid signaling pathway	5/524	162/7206	0.0321981613959
ko04912	GnRH signaling pathway	3/524	122/7206	0.0340523820924
ko04666	Fc gamma R-mediated phagocytosis	3/524	122/7206	0.0340523820924
ko04066	HIF-1 signaling pathway	3/524	123/7206	0.0341638065553
ko04062	Chemokine signaling pathway	7/524	201/7206	0.0373613349283
ko05140	Leishmaniasis	1/524	75/7206	0.0423004469949
ko04612	Antigen processing and presentation	1/524	77/7206	0.0431807904533
ko04658	Th1 and Th2 cell differentiation	2/524	96/7206	0.0463565364154
ko00564	Glycerophospholipid metabolism	2/524	99/7206	0.0477126775433
ko04620	Toll-like receptor signaling pathway	2/524	100/7206	0.0485188371356
ko04139	Mitophagy - yeast	6/524	37/7206	0.0486034472986