ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	143/862	423/7206	1.71942107507e-34
ko05033	Nicotine addiction	40/862	56/7206	3.58935976032e-25
ko04721	Synaptic vesicle cycle	47/862	80/7206	9.44214044023e-24
ko04724	Glutamatergic synapse	66/862	152/7206	6.13355174353e-23
ko04728	Dopaminergic synapse	71/862	185/7206	7.89408451203e-21
ko05032	Morphine addiction	48/862	110/7206	4.41564087015e-17
ko04727	GABAergic synapse	47/862	110/7206	2.61268165332e-16
ko04713	Circadian entrainment	53/862	136/7206	3.77791251386e-16
ko04725	Cholinergic synapse	56/862	160/7206	1.37415749057e-14
ko04723	Retrograde endocannabinoid signaling	58/862	175/7206	7.13183629441e-14
ko04911	Insulin secretion	42/862	117/7206	1.1626869647e-11
ko04024	cAMP signaling pathway	73/862	279/7206	2.67187225341e-11
ko04726	Serotonergic synapse	45/862	137/7206	6.88564278614e-11
ko05031	Amphetamine addiction	34/862	91/7206	3.16311405098e-10
ko04742	Taste transduction	25/862	61/7206	7.93064417648e-09
ko04360	Axon guidance	58/862	233/7206	2.62174955809e-08
ko04966	Collecting duct acid secretion	15/862	26/7206	2.82111306037e-08
ko04261	Adrenergic signaling in cardiomyocytes	53/862	205/7206	3.64349493491e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	26/862	74/7206	1.66922297105e-07
ko04720	Long-term potentiation	31/862	99/7206	2.24359319391e-07
ko03040	Spliceosome	1/862	145/7206	3.62232204355e-07
ko04921	Oxytocin signaling pathway	51/862	209/7206	3.76037271327e-07
ko05030	Cocaine addiction	25/862	73/7206	5.05685752276e-07
ko04020	Calcium signaling pathway	60/862	265/7206	5.92102919486e-07
ko04120	Ubiquitin mediated proteolysis	1/862	138/7206	8.10228488497e-07
ko04514	Cell adhesion molecules (CAMs)	35/862	130/7206	3.17180977696e-06
ko04060	Cytokine-cytokine receptor interaction	5/862	191/7206	4.27617586629e-06
ko04744	Phototransduction	15/862	36/7206	6.35926065925e-06
ko05203	Viral carcinogenesis	12/862	277/7206	1.15911332594e-05
ko05168	Herpes simplex infection	5/862	182/7206	1.29433532495e-05
ko04970	Salivary secretion	27/862	95/7206	1.55880897842e-05
ko04010	MAPK signaling pathway	64/862	321/7206	2.95506450708e-05
ko04141	Protein processing in endoplasmic reticulum	6/862	184/7206	4.32477570572e-05
ko03013	RNA transport	5/862	166/7206	5.29892322371e-05
ko05164	Influenza A	5/862	167/7206	5.30343282035e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/862	14/7206	6.28434589248e-05
ko05110	Vibrio cholerae infection	19/862	63/7206	8.79845463217e-05
ko04621	NOD-like receptor signaling pathway	5/862	157/7206	0.000152735935762
ko04971	Gastric acid secretion	25/862	98/7206	0.000205374004039
ko04925	Aldosterone synthesis and secretion	26/862	105/7206	0.000216395846575
ko04730	Long-term depression	21/862	78/7206	0.000275624405249
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/862	59/7206	0.000375353654589
ko04924	Renin secretion	22/862	86/7206	0.000572511926962
ko03008	Ribosome biogenesis in eukaryotes	1/862	79/7206	0.000754908554685
ko05322	Systemic lupus erythematosus	6/862	151/7206	0.000891287621028
ko05120	Epithelial cell signaling in Helicobacter pylori infection	22/862	92/7206	0.00108371164033
ko04745	Phototransduction - fly	12/862	38/7206	0.00110920603961
ko05162	Measles	4/862	120/7206	0.00154414816644
ko04146	Peroxisome	2/862	89/7206	0.00157359576569
ko04740	Olfactory transduction	19/862	80/7206	0.00273237067702
ko04540	Gap junction	27/862	128/7206	0.00341848719403
ko04064	NF-kappa B signaling pathway	3/862	96/7206	0.00389888188747
ko04022	cGMP-PKG signaling pathway	40/862	216/7206	0.00395938957862
ko04972	Pancreatic secretion	24/862	111/7206	0.00445133027111
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/862	182/7206	0.00510688457126
ko04964	Proximal tubule bicarbonate reclamation	9/862	29/7206	0.00521480396459
ko00561	Glycerolipid metabolism	1/862	63/7206	0.00545312154097
ko04612	Antigen processing and presentation	2/862	77/7206	0.00704805076671
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/862	79/7206	0.00759651604986
ko04014	Ras signaling pathway	48/862	279/7206	0.00822791679705
ko01200	Carbon metabolism	6/862	128/7206	0.00833217319787
ko05166	HTLV-I infection	21/862	292/7206	0.00962085912926
ko05205	Proteoglycans in cancer	19/862	271/7206	0.00963847826712
ko00240	Pyrimidine metabolism	5/862	110/7206	0.0114035504756
ko00480	Glutathione metabolism	1/862	55/7206	0.0118350607529
ko05321	Inflammatory bowel disease (IBD)	1/862	56/7206	0.0118587108932
ko04391	Hippo signaling pathway - fly	19/862	90/7206	0.0128719337378
ko04110	Cell cycle	8/862	145/7206	0.0133970992291
ko04145	Phagosome	30/862	162/7206	0.0137215352355
ko04630	Jak-STAT signaling pathway	7/862	132/7206	0.0142465742501
ko03018	RNA degradation	3/862	84/7206	0.0161781262132
ko00590	Arachidonic acid metabolism	1/862	52/7206	0.0174065630759
ko05161	Hepatitis B	11/862	173/7206	0.0176384912027
ko00280	Valine, leucine and isoleucine degradation	1/862	54/7206	0.0180162870539
ko05323	Rheumatoid arthritis	18/862	89/7206	0.0209863852061
ko05169	Epstein-Barr virus infection	14/862	206/7206	0.0214277791587
ko04962	Vasopressin-regulated water reabsorption	13/862	58/7206	0.0228335478793
ko04750	Inflammatory mediator regulation of TRP channels	23/862	122/7206	0.0237139631961
ko05219	Bladder cancer	1/862	48/7206	0.0256343769874
ko04260	Cardiac muscle contraction	19/862	98/7206	0.0280060641684
ko00330	Arginine and proline metabolism	2/862	61/7206	0.0291454357256
ko04915	Estrogen signaling pathway	24/862	131/7206	0.0292343749725
ko05140	Leishmaniasis	3/862	75/7206	0.0303605271932
ko04640	Hematopoietic cell lineage	2/862	64/7206	0.0303852989795
ko04976	Bile secretion	16/862	80/7206	0.0357120158043
ko00071	Fatty acid degradation	1/862	45/7206	0.0375226301205
ko04140	Autophagy - animal	11/862	164/7206	0.0375910461033
ko00620	Pyruvate metabolism	1/862	46/7206	0.0377834806679
ko03420	Nucleotide excision repair	1/862	46/7206	0.0377834806679
ko04214	Apoptosis - fly	3/862	72/7206	0.0424836269862
ko04210	Apoptosis	13/862	180/7206	0.0475844979435
ko04071	Sphingolipid signaling pathway	28/862	162/7206	0.0487306714229