ko pathway ratio_in_study ratio_in_pop p_value ko04713 Circadian entrainment 19/228 136/7206 4.28101273616e-08 ko04724 Glutamatergic synapse 19/228 152/7206 2.60898655797e-07 ko04921 Oxytocin signaling pathway 22/228 209/7206 6.11083567738e-07 ko04911 Insulin secretion 16/228 117/7206 7.00250762742e-07 ko04725 Cholinergic synapse 17/228 160/7206 1.08093561559e-05 ko04745 Phototransduction - fly 8/228 38/7206 1.91175617827e-05 ko04727 GABAergic synapse 13/228 110/7206 3.94748370009e-05 ko05032 Morphine addiction 13/228 110/7206 3.94748370009e-05 ko04070 Phosphatidylinositol signaling system 13/228 112/7206 4.78265077102e-05 ko04710 Circadian rhythm 8/228 43/7206 4.94500518496e-05 ko05033 Nicotine addiction 9/228 56/7206 5.62222155586e-05 ko04720 Long-term potentiation 12/228 99/7206 6.10583275293e-05 ko00680 Methane metabolism 7/228 34/7206 7.50658789207e-05 ko04925 Aldosterone synthesis and secretion 12/228 105/7206 0.000109034721274 ko04723 Retrograde endocannabinoid signaling 16/228 175/7206 0.000123857664474 ko04726 Serotonergic synapse 13/228 137/7206 0.000373840617679 ko00010 Glycolysis / Gluconeogenesis 9/228 74/7206 0.000500369029008 ko05031 Amphetamine addiction 10/228 91/7206 0.000561511221001 ko04728 Dopaminergic synapse 15/228 185/7206 0.000733861942367 ko04730 Long-term depression 9/228 78/7206 0.000739967740457 ko04970 Salivary secretion 10/228 95/7206 0.000790718057658 ko04721 Synaptic vesicle cycle 9/228 80/7206 0.000890866387067 ko04740 Olfactory transduction 9/228 80/7206 0.000890866387067 ko04966 Collecting duct acid secretion 5/228 26/7206 0.00115847183432 ko04626 Plant-pathogen interaction 4/228 18/7206 0.00210542790285 ko04922 Glucagon signaling pathway 11/228 128/7206 0.00234584715243 ko04261 Adrenergic signaling in cardiomyocytes 15/228 205/7206 0.00331749450154 ko05110 Vibrio cholerae infection 7/228 63/7206 0.00354760131271 ko04971 Gastric acid secretion 9/228 98/7206 0.00369997727094 ko04066 HIF-1 signaling pathway 10/228 123/7206 0.00544301614703 ko04020 Calcium signaling pathway 17/228 265/7206 0.00596441196722 ko00190 Oxidative phosphorylation 10/228 127/7206 0.0068016636051 ko04711 Circadian rhythm - fly 3/228 13/7206 0.00706784096039 ko00051 Fructose and mannose metabolism 5/228 42/7206 0.00994411881958 ko04912 GnRH signaling pathway 9/228 122/7206 0.0149679543511 ko04750 Inflammatory mediator regulation of TRP channels 9/228 122/7206 0.0149679543511 ko01230 Biosynthesis of amino acids 7/228 85/7206 0.017670545817 ko01200 Carbon metabolism 9/228 128/7206 0.019902239059 ko04360 Axon guidance 14/228 233/7206 0.0200395032132 ko04024 cAMP signaling pathway 16/228 279/7206 0.0211406163809 ko05166 HTLV-I infection 3/228 292/7206 0.0261062666523 ko05168 Herpes simplex infection 1/228 182/7206 0.0315010599522 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/228 1/7206 0.0316402997502 ko04060 Cytokine-cytokine receptor interaction 1/228 191/7206 0.0325050675218 ko04260 Cardiac muscle contraction 7/228 98/7206 0.0352140556227 ko04722 Neurotrophin signaling pathway 10/228 160/7206 0.0356653779677 ko04510 Focal adhesion 2/228 240/7206 0.0360699632825 ko05214 Glioma 6/228 79/7206 0.0384322114389 ko04138 Autophagy - yeast 6/228 81/7206 0.0426292910014 ko04114 Oocyte meiosis 9/228 139/7206 0.0428036297027 ko04068 FoxO signaling pathway 10/228 167/7206 0.0431595521083 ko05224 Breast cancer 1/228 174/7206 0.0455929882342