ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	152/906	423/7206	1.18639247158e-37
ko04724	Glutamatergic synapse	73/906	152/7206	2.62818040647e-27
ko05033	Nicotine addiction	42/906	56/7206	6.46321700341e-27
ko04728	Dopaminergic synapse	76/906	185/7206	4.87794449801e-23
ko04721	Synaptic vesicle cycle	46/906	80/7206	8.44947328963e-22
ko05032	Morphine addiction	54/906	110/7206	5.11339807486e-21
ko04713	Circadian entrainment	59/906	136/7206	1.70369661681e-19
ko04727	GABAergic synapse	52/906	110/7206	2.39841399874e-19
ko04725	Cholinergic synapse	61/906	160/7206	8.52727128902e-17
ko04723	Retrograde endocannabinoid signaling	63/906	175/7206	6.91385290799e-16
ko04024	cAMP signaling pathway	81/906	279/7206	8.41291890479e-14
ko04726	Serotonergic synapse	50/906	137/7206	4.0827572685e-13
ko04742	Taste transduction	29/906	61/7206	2.01410828777e-11
ko04911	Insulin secretion	42/906	117/7206	5.95599751773e-11
ko04744	Phototransduction	21/906	36/7206	8.53431415672e-11
ko05031	Amphetamine addiction	35/906	91/7206	2.71940700708e-10
ko04921	Oxytocin signaling pathway	58/906	209/7206	2.04290148749e-09
ko04020	Calcium signaling pathway	68/906	265/7206	3.73559716943e-09
ko04261	Adrenergic signaling in cardiomyocytes	55/906	205/7206	2.16866248407e-08
ko04720	Long-term potentiation	33/906	99/7206	5.62053810384e-08
ko05203	Viral carcinogenesis	9/906	277/7206	8.08594722458e-08
ko03040	Spliceosome	1/906	145/7206	9.1894830986e-08
ko04970	Salivary secretion	30/906	95/7206	8.47087350219e-07
ko04360	Axon guidance	56/906	233/7206	9.53695893754e-07
ko05030	Cocaine addiction	25/906	73/7206	1.3013908609e-06
ko04060	Cytokine-cytokine receptor interaction	5/906	191/7206	1.33627928613e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/906	74/7206	1.73487084877e-06
ko04740	Olfactory transduction	26/906	80/7206	2.48464832635e-06
ko04120	Ubiquitin mediated proteolysis	2/906	138/7206	3.13290496229e-06
ko04966	Collecting duct acid secretion	13/906	26/7206	3.87142235459e-06
ko05164	Influenza A	4/906	167/7206	4.58355632982e-06
ko04971	Gastric acid secretion	28/906	98/7206	1.84979931461e-05
ko04010	MAPK signaling pathway	67/906	321/7206	2.02773747308e-05
ko05168	Herpes simplex infection	6/906	182/7206	2.05281282665e-05
ko03013	RNA transport	5/906	166/7206	2.48428307108e-05
ko05322	Systemic lupus erythematosus	4/906	151/7206	2.96108915891e-05
ko04621	NOD-like receptor signaling pathway	5/906	157/7206	7.38106801694e-05
ko04514	Cell adhesion molecules (CAMs)	33/906	130/7206	7.43232604353e-05
ko04925	Aldosterone synthesis and secretion	28/906	105/7206	7.71845112029e-05
ko04730	Long-term depression	23/906	78/7206	8.09896017194e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/906	14/7206	9.04013958561e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/906	79/7206	9.10617535702e-05
ko04745	Phototransduction - fly	14/906	38/7206	0.000116166481465
ko04972	Pancreatic secretion	28/906	111/7206	0.000231804360649
ko04141	Protein processing in endoplasmic reticulum	8/906	184/7206	0.000259795156913
ko05205	Proteoglycans in cancer	16/906	271/7206	0.000351028322322
ko03008	Ribosome biogenesis in eukaryotes	1/906	79/7206	0.000487998345296
ko04014	Ras signaling pathway	55/906	279/7206	0.000595642268578
ko04924	Renin secretion	22/906	86/7206	0.000847980213602
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/906	59/7206	0.0010228697983
ko04260	Cardiac muscle contraction	24/906	98/7206	0.00104112908383
ko04022	cGMP-PKG signaling pathway	44/906	216/7206	0.0011139605751
ko05161	Hepatitis B	9/906	173/7206	0.0016098633336
ko05169	Epstein-Barr virus infection	12/906	206/7206	0.00185051748705
ko04964	Proximal tubule bicarbonate reclamation	10/906	29/7206	0.00197623674629
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/906	182/7206	0.00207695357448
ko04064	NF-kappa B signaling pathway	3/906	96/7206	0.00273292195668
ko05162	Measles	5/906	120/7206	0.00314085983383
ko00561	Glycerolipid metabolism	1/906	63/7206	0.0035691477532
ko04640	Hematopoietic cell lineage	1/906	64/7206	0.00364561521257
ko05166	HTLV-I infection	21/906	292/7206	0.00375518903267
ko01200	Carbon metabolism	6/906	128/7206	0.0043306942821
ko04626	Plant-pathogen interaction	7/906	18/7206	0.00439447025922
ko05140	Leishmaniasis	2/906	75/7206	0.0046576781153
ko04612	Antigen processing and presentation	2/906	77/7206	0.00481293250117
ko00330	Arginine and proline metabolism	1/906	61/7206	0.0054466491269
ko05110	Vibrio cholerae infection	16/906	63/7206	0.00606809933857
ko04110	Cell cycle	8/906	145/7206	0.00740491843261
ko03018	RNA degradation	3/906	84/7206	0.00760219233455
ko04630	Jak-STAT signaling pathway	7/906	132/7206	0.00772926027336
ko00240	Pyrimidine metabolism	5/906	110/7206	0.00830055010164
ko04140	Autophagy - animal	10/906	164/7206	0.00851388110516
ko00480	Glutathione metabolism	1/906	55/7206	0.0121334212388
ko05414	Dilated cardiomyopathy	23/906	112/7206	0.0143409973286
ko04540	Gap junction	26/906	128/7206	0.0144678483738
ko04146	Peroxisome	4/906	89/7206	0.0154625715501
ko00590	Arachidonic acid metabolism	1/906	52/7206	0.0180820038015
ko01524	Platinum drug resistance	3/906	76/7206	0.0218393083811
ko04391	Hippo signaling pathway - fly	19/906	90/7206	0.0232984511744
ko04668	TNF signaling pathway	7/906	120/7206	0.0250986294738
ko03420	Nucleotide excision repair	1/906	46/7206	0.0251139782143
ko05120	Epithelial cell signaling in Helicobacter pylori infection	19/906	92/7206	0.0256199825439
ko05219	Bladder cancer	1/906	48/7206	0.0258592230587
ko04750	Inflammatory mediator regulation of TRP channels	24/906	122/7206	0.0261977377756
ko04214	Apoptosis - fly	3/906	72/7206	0.0301039097676
ko04070	Phosphatidylinositol signaling system	22/906	112/7206	0.0301863685239
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/906	15/7206	0.0316286340525
ko04915	Estrogen signaling pathway	25/906	131/7206	0.0321213493035
ko05410	Hypertrophic cardiomyopathy (HCM)	20/906	100/7206	0.0322056172429
ko03022	Basal transcription factors	1/906	44/7206	0.0373014459002
ko00071	Fatty acid degradation	1/906	45/7206	0.038318330998
ko04930	Type II diabetes mellitus	12/906	54/7206	0.0391267451015
ko04722	Neurotrophin signaling pathway	29/906	160/7206	0.0395741912413
ko05321	Inflammatory bowel disease (IBD)	2/906	56/7206	0.0410043384367
ko05215	Prostate cancer	7/906	111/7206	0.0430763520446