ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	147/806	423/7206	1.00110718871e-40
ko05033	Nicotine addiction	43/806	56/7206	2.02426193116e-30
ko04724	Glutamatergic synapse	72/806	152/7206	9.48825331901e-30
ko05032	Morphine addiction	53/806	110/7206	1.43572041553e-22
ko04727	GABAergic synapse	52/806	110/7206	1.10968601915e-21
ko04728	Dopaminergic synapse	69/806	185/7206	4.0070881093e-21
ko04713	Circadian entrainment	55/806	136/7206	6.27399435167e-19
ko04723	Retrograde endocannabinoid signaling	63/806	175/7206	1.8751480686e-18
ko04721	Synaptic vesicle cycle	38/806	80/7206	3.02768487192e-16
ko04024	cAMP signaling pathway	78/806	279/7206	2.70756226488e-15
ko04725	Cholinergic synapse	55/806	160/7206	3.10422201332e-15
ko04020	Calcium signaling pathway	69/806	265/7206	5.43222520265e-12
ko04911	Insulin secretion	41/806	117/7206	5.64635422225e-12
ko04726	Serotonergic synapse	44/806	137/7206	2.74770076731e-11
ko04921	Oxytocin signaling pathway	58/806	209/7206	2.86081473528e-11
ko05031	Amphetamine addiction	34/806	91/7206	4.98821455178e-11
ko04261	Adrenergic signaling in cardiomyocytes	56/806	205/7206	9.47809873729e-11
ko04744	Phototransduction	19/806	36/7206	9.2516072262e-10
ko04720	Long-term potentiation	33/806	99/7206	2.98891753955e-09
ko04742	Taste transduction	24/806	61/7206	1.08737680873e-08
ko05030	Cocaine addiction	26/806	73/7206	3.06598763283e-08
ko04010	MAPK signaling pathway	67/806	321/7206	2.5939461297e-07
ko03040	Spliceosome	1/806	145/7206	8.49788489437e-07
ko04970	Salivary secretion	28/806	95/7206	8.59075945009e-07
ko05203	Viral carcinogenesis	9/806	277/7206	2.12982909531e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	23/806	74/7206	2.99102843092e-06
ko04260	Cardiac muscle contraction	27/806	98/7206	5.61284624569e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/806	79/7206	1.02058986734e-05
ko04925	Aldosterone synthesis and secretion	28/806	105/7206	1.10556646576e-05
ko04514	Cell adhesion molecules (CAMs)	32/806	130/7206	1.37684563955e-05
ko04060	Cytokine-cytokine receptor interaction	5/806	191/7206	1.98941172667e-05
ko05164	Influenza A	4/806	167/7206	3.25359630325e-05
ko04971	Gastric acid secretion	25/806	98/7206	5.99205789829e-05
ko04072	Phospholipase D signaling pathway	41/806	197/7206	7.48829902201e-05
ko04730	Long-term depression	21/806	78/7206	8.80046113529e-05
ko04022	cGMP-PKG signaling pathway	43/806	216/7206	0.000158296054734
ko04972	Pancreatic secretion	26/806	111/7206	0.000197003154525
ko05322	Systemic lupus erythematosus	4/806	151/7206	0.000200277133046
ko04740	Olfactory transduction	21/806	80/7206	0.000202304998484
ko05169	Epstein-Barr virus infection	8/806	206/7206	0.000279281948767
ko04621	NOD-like receptor signaling pathway	5/806	157/7206	0.000453489141919
ko05168	Herpes simplex infection	7/806	182/7206	0.000505871126108
ko04141	Protein processing in endoplasmic reticulum	7/806	184/7206	0.000508964873208
ko04120	Ubiquitin mediated proteolysis	4/806	138/7206	0.000562845246284
ko04745	Phototransduction - fly	12/806	38/7206	0.000604419677503
ko03013	RNA transport	6/806	166/7206	0.000672625150587
ko05162	Measles	3/806	120/7206	0.000682336779222
ko04350	TGF-beta signaling pathway	2/806	103/7206	0.000777849019386
ko04110	Cell cycle	5/806	145/7206	0.00123134639518
ko04966	Collecting duct acid secretion	9/806	26/7206	0.00140367233528
ko04612	Antigen processing and presentation	1/806	77/7206	0.0017394635588
ko03008	Ribosome biogenesis in eukaryotes	1/806	79/7206	0.00177742225922
ko05215	Prostate cancer	3/806	111/7206	0.00202976647454
ko04550	Signaling pathways regulating pluripotency of stem cells	7/806	165/7206	0.0024568709367
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/806	14/7206	0.00261362716973
ko04924	Renin secretion	19/806	86/7206	0.0029867149042
ko05205	Proteoglycans in cancer	16/806	271/7206	0.00314315027138
ko05161	Hepatitis B	8/806	173/7206	0.00322382420914
ko04964	Proximal tubule bicarbonate reclamation	9/806	29/7206	0.00330656298507
ko04014	Ras signaling pathway	47/806	279/7206	0.00352642277936
ko05414	Dilated cardiomyopathy	23/806	112/7206	0.0035689363856
ko04070	Phosphatidylinositol signaling system	23/806	112/7206	0.0035689363856
ko05410	Hypertrophic cardiomyopathy (HCM)	21/806	100/7206	0.00363711951177
ko04214	Apoptosis - fly	1/806	72/7206	0.00391047361293
ko05166	HTLV-I infection	18/806	292/7206	0.00425976645428
ko04064	NF-kappa B signaling pathway	3/806	96/7206	0.00816407114236
ko04640	Hematopoietic cell lineage	1/806	64/7206	0.00835118266596
ko00240	Pyrimidine metabolism	4/806	110/7206	0.00865402408362
ko04540	Gap junction	24/806	128/7206	0.0101601764961
ko05200	Pathways in cancer	38/806	492/7206	0.0115278801058
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/806	182/7206	0.0118004750805
ko04510	Focal adhesion	15/806	240/7206	0.0120254209886
ko05110	Vibrio cholerae infection	14/806	63/7206	0.0134941771295
ko00310	Lysine degradation	2/806	73/7206	0.0146577703581
ko04360	Axon guidance	38/806	233/7206	0.0148977651048
ko05140	Leishmaniasis	2/806	75/7206	0.0149745874423
ko04915	Estrogen signaling pathway	24/806	131/7206	0.0162105260468
ko04146	Peroxisome	3/806	89/7206	0.0162625725234
ko00480	Glutathione metabolism	1/806	55/7206	0.0178984427046
ko03320	PPAR signaling pathway	2/806	69/7206	0.0209382814453
ko03018	RNA degradation	3/806	84/7206	0.0222871004097
ko04630	Jak-STAT signaling pathway	7/806	132/7206	0.0257185834282
ko04217	Necroptosis	11/806	178/7206	0.0297941548168
ko04210	Apoptosis	11/806	180/7206	0.0301309307351
ko04140	Autophagy - animal	10/806	164/7206	0.0330913209272
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/806	59/7206	0.0354768510728
ko05034	Alcoholism	37/806	238/7206	0.0359516218239
ko05231	Choline metabolism in cancer	23/806	134/7206	0.0365159885016
ko00260	Glycine, serine and threonine metabolism	1/806	48/7206	0.038316436578
ko05010	Alzheimer's disease	32/806	202/7206	0.0407538725679
ko04750	Inflammatory mediator regulation of TRP channels	21/806	122/7206	0.0414072481216
ko05222	Small cell lung cancer	4/806	89/7206	0.0415881646248
ko04330	Notch signaling pathway	2/806	62/7206	0.0422429080036
ko01524	Platinum drug resistance	3/806	76/7206	0.0428956267644
ko04626	Plant-pathogen interaction	5/806	18/7206	0.0429092170355
ko04973	Carbohydrate digestion and absorption	9/806	42/7206	0.0461940113883
ko04976	Bile secretion	15/806	80/7206	0.0466666745537
ko04930	Type II diabetes mellitus	11/806	54/7206	0.0468014751727