ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	150/884	423/7206	1.09109286323e-37
ko04724	Glutamatergic synapse	69/884	152/7206	1.11122039608e-24
ko05033	Nicotine addiction	39/884	56/7206	1.6830408327e-23
ko04728	Dopaminergic synapse	65/884	185/7206	2.71322595754e-16
ko04713	Circadian entrainment	53/884	136/7206	1.12867410962e-15
ko04727	GABAergic synapse	46/884	110/7206	3.93954548897e-15
ko05032	Morphine addiction	46/884	110/7206	3.93954548897e-15
ko04721	Synaptic vesicle cycle	38/884	80/7206	6.65327485511e-15
ko04725	Cholinergic synapse	55/884	160/7206	1.67133067627e-13
ko04723	Retrograde endocannabinoid signaling	58/884	175/7206	2.16816386733e-13
ko04024	cAMP signaling pathway	78/884	279/7206	5.01047275111e-13
ko04020	Calcium signaling pathway	74/884	265/7206	2.3062848616e-12
ko04726	Serotonergic synapse	46/884	137/7206	4.2975181378e-11
ko04911	Insulin secretion	39/884	117/7206	1.69386767676e-09
ko05031	Amphetamine addiction	33/884	91/7206	2.73817273453e-09
ko04921	Oxytocin signaling pathway	56/884	209/7206	6.13586529628e-09
ko04970	Salivary secretion	31/884	95/7206	1.39688927816e-07
ko04720	Long-term potentiation	31/884	99/7206	3.9626218832e-07
ko03010	Ribosome	1/884	129/7206	1.13723013664e-06
ko04744	Phototransduction	16/884	36/7206	1.54158438354e-06
ko04514	Cell adhesion molecules (CAMs)	36/884	130/7206	2.02319291362e-06
ko03040	Spliceosome	2/884	145/7206	2.2003120359e-06
ko04971	Gastric acid secretion	29/884	98/7206	3.39547821692e-06
ko04742	Taste transduction	21/884	61/7206	5.63011176911e-06
ko03013	RNA transport	4/884	166/7206	6.78358841873e-06
ko05322	Systemic lupus erythematosus	3/884	151/7206	7.26891186498e-06
ko05030	Cocaine addiction	23/884	73/7206	1.11123279242e-05
ko04360	Axon guidance	52/884	233/7206	1.50732420366e-05
ko04925	Aldosterone synthesis and secretion	29/884	105/7206	1.60476719256e-05
ko04261	Adrenergic signaling in cardiomyocytes	47/884	205/7206	1.83746722947e-05
ko05203	Viral carcinogenesis	13/884	277/7206	2.14883243115e-05
ko04710	Circadian rhythm	16/884	43/7206	2.42402939939e-05
ko04022	cGMP-PKG signaling pathway	48/884	216/7206	3.13243932803e-05
ko04120	Ubiquitin mediated proteolysis	3/884	138/7206	3.34105308732e-05
ko04070	Phosphatidylinositol signaling system	29/884	112/7206	6.26494272708e-05
ko04014	Ras signaling pathway	57/884	279/7206	7.93137742325e-05
ko04966	Collecting duct acid secretion	11/884	26/7206	0.000119408318324
ko04730	Long-term depression	22/884	78/7206	0.000147831315203
ko05164	Influenza A	6/884	167/7206	0.000171268226255
ko05014	Amyotrophic lateral sclerosis (ALS)	21/884	74/7206	0.000205275062467
ko05168	Herpes simplex infection	8/884	182/7206	0.00035253356454
ko04972	Pancreatic secretion	27/884	111/7206	0.000368556050729
ko04745	Phototransduction - fly	13/884	38/7206	0.000370312728409
ko04626	Plant-pathogen interaction	8/884	18/7206	0.000700311447622
ko04612	Antigen processing and presentation	1/884	77/7206	0.000741214848624
ko04141	Protein processing in endoplasmic reticulum	9/884	184/7206	0.000894633751071
ko05162	Measles	4/884	120/7206	0.00106709570781
ko04110	Cell cycle	6/884	145/7206	0.00122254855001
ko04621	NOD-like receptor signaling pathway	7/884	157/7206	0.00124167954607
ko04072	Phospholipase D signaling pathway	40/884	197/7206	0.00125445418154
ko04750	Inflammatory mediator regulation of TRP channels	27/884	122/7206	0.00192841123452
ko05169	Epstein-Barr virus infection	12/884	206/7206	0.00247410121629
ko04960	Aldosterone-regulated sodium reabsorption	12/884	41/7206	0.00285858807577
ko05110	Vibrio cholerae infection	16/884	63/7206	0.0033825589912
ko04010	MAPK signaling pathway	57/884	321/7206	0.00389275061329
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/884	14/7206	0.00420231945805
ko05166	HTLV-I infection	21/884	292/7206	0.00605295354539
ko04964	Proximal tubule bicarbonate reclamation	9/884	29/7206	0.0061687251537
ko05140	Leishmaniasis	2/884	75/7206	0.00694252266771
ko05016	Huntington's disease	14/884	215/7206	0.00792883677815
ko00562	Inositol phosphate metabolism	20/884	89/7206	0.0081502988049
ko04015	Rap1 signaling pathway	49/884	278/7206	0.00870184634865
ko04630	Jak-STAT signaling pathway	7/884	132/7206	0.0105189341515
ko05205	Proteoglycans in cancer	20/884	271/7206	0.0106021480041
ko00280	Valine, leucine and isoleucine degradation	1/884	54/7206	0.011686095773
ko05161	Hepatitis B	11/884	173/7206	0.0134802102218
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/884	59/7206	0.014408610044
ko04711	Circadian rhythm - fly	5/884	13/7206	0.0151646576826
ko04540	Gap junction	25/884	128/7206	0.0196374263812
ko04924	Renin secretion	18/884	86/7206	0.0196992629179
ko04217	Necroptosis	12/884	178/7206	0.0203336098772
ko04740	Olfactory transduction	17/884	80/7206	0.0237515068802
ko05219	Bladder cancer	1/884	48/7206	0.0254484369934
ko00240	Pyrimidine metabolism	6/884	110/7206	0.0269446142684
ko04214	Apoptosis - fly	3/884	72/7206	0.0299434224695
ko04060	Cytokine-cytokine receptor interaction	14/884	191/7206	0.0333929761544
ko04371	Apelin signaling pathway	31/884	177/7206	0.0364569069209
ko03022	Basal transcription factors	1/884	44/7206	0.037213392569
ko05120	Epithelial cell signaling in Helicobacter pylori infection	18/884	92/7206	0.0374900356216
ko04210	Apoptosis	13/884	180/7206	0.0376342203577
ko04071	Sphingolipid signaling pathway	29/884	162/7206	0.0382676624874
ko03420	Nucleotide excision repair	1/884	46/7206	0.0384894122619
ko05145	Toxoplasmosis	8/884	126/7206	0.0394534011497
ko04260	Cardiac muscle contraction	19/884	98/7206	0.0419607983868