ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko00120	Primary bile acid biosynthesis	13/524	20/7206	6.6515227177e-11
ko00071	Fatty acid degradation	17/524	45/7206	5.59441859199e-09
ko00380	Tryptophan metabolism	17/524	50/7206	3.54269458755e-08
ko04610	Complement and coagulation cascades	20/524	79/7206	5.49100838342e-07
ko04146	Peroxisome	21/524	89/7206	1.01352848285e-06
ko00350	Tyrosine metabolism	12/524	33/7206	1.66265940001e-06
ko00640	Propanoate metabolism	12/524	34/7206	2.40193065497e-06
ko01200	Carbon metabolism	25/524	128/7206	4.09379093598e-06
ko05150	Staphylococcus aureus infection	12/524	36/7206	4.79102936885e-06
ko03320	PPAR signaling pathway	17/524	69/7206	5.83456042505e-06
ko00362	Benzoate degradation	5/524	6/7206	1.1264889594e-05
ko01212	Fatty acid metabolism	15/524	60/7206	1.70857079751e-05
ko00500	Starch and sucrose metabolism	11/524	35/7206	2.26271897943e-05
ko00643	Styrene degradation	4/524	4/7206	2.76646920545e-05
ko05034	Alcoholism	3/524	238/7206	3.35847363756e-05
ko00982	Drug metabolism - cytochrome P450	11/524	37/7206	4.05639721129e-05
ko04974	Protein digestion and absorption	19/524	96/7206	4.838138078e-05
ko00360	Phenylalanine metabolism	7/524	17/7206	0.00010557148239
ko00140	Steroid hormone biosynthesis	11/524	41/7206	0.000114765754987
ko05204	Chemical carcinogenesis	12/524	48/7206	0.000119025435589
ko00592	alpha-Linolenic acid metabolism	7/524	19/7206	0.000240570297556
ko00920	Sulfur metabolism	5/524	10/7206	0.000369705048336
ko00280	Valine, leucine and isoleucine degradation	12/524	54/7206	0.000392166118306
ko00980	Metabolism of xenobiotics by cytochrome P450	10/524	40/7206	0.000438278578963
ko03040	Spliceosome	1/524	145/7206	0.000486463033791
ko00983	Drug metabolism - other enzymes	10/524	42/7206	0.000666755459971
ko00830	Retinol metabolism	10/524	42/7206	0.000666755459971
ko05203	Viral carcinogenesis	7/524	277/7206	0.000837076757118
ko03010	Ribosome	1/524	129/7206	0.000974633599041
ko00330	Arginine and proline metabolism	12/524	61/7206	0.00124854391806
ko00620	Pyruvate metabolism	10/524	46/7206	0.00141947986418
ko00960	Tropane, piperidine and pyridine alkaloid biosynthesis	3/524	4/7206	0.0014469005639
ko01040	Biosynthesis of unsaturated fatty acids	7/524	25/7206	0.00156420830528
ko00051	Fructose and mannose metabolism	9/524	42/7206	0.00270653957391
ko00410	beta-Alanine metabolism	8/524	35/7206	0.00301696681877
ko00100	Steroid biosynthesis	6/524	21/7206	0.00303454515091
ko03013	RNA transport	3/524	166/7206	0.00347502036744
ko04144	Endocytosis	12/524	342/7206	0.0038306089363
ko00950	Isoquinoline alkaloid biosynthesis	4/524	10/7206	0.004074761522
ko04727	GABAergic synapse	1/524	110/7206	0.00457884318877
ko05032	Morphine addiction	1/524	110/7206	0.00457884318877
ko00720	Carbon fixation pathways in prokaryotes	5/524	17/7206	0.00592242181921
ko00310	Lysine degradation	12/524	73/7206	0.00594305226537
ko04060	Cytokine-cytokine receptor interaction	24/524	191/7206	0.0070589447899
ko04723	Retrograde endocannabinoid signaling	4/524	175/7206	0.00718252439509
ko00040	Pentose and glucuronate interconversions	6/524	26/7206	0.00943877559355
ko00650	Butanoate metabolism	6/524	26/7206	0.00943877559355
ko00565	Ether lipid metabolism	8/524	42/7206	0.00966405902
ko04390	Hippo signaling pathway	5/524	188/7206	0.00977409593689
ko00010	Glycolysis / Gluconeogenesis	12/524	74/7206	0.0102775821628
ko04380	Osteoclast differentiation	18/524	134/7206	0.0105394510706
ko00590	Arachidonic acid metabolism	9/524	52/7206	0.0116946391756
ko04310	Wnt signaling pathway	5/524	181/7206	0.0132028264412
ko04728	Dopaminergic synapse	5/524	185/7206	0.0136142904003
ko03015	mRNA surveillance pathway	1/524	93/7206	0.0140659380256
ko04922	Glucagon signaling pathway	17/524	128/7206	0.0146261259691
ko00480	Glutathione metabolism	9/524	55/7206	0.0166673176972
ko00630	Glyoxylate and dicarboxylate metabolism	7/524	38/7206	0.018077154353
ko04120	Ubiquitin mediated proteolysis	3/524	138/7206	0.0186230887306
ko00053	Ascorbate and aldarate metabolism	5/524	22/7206	0.0186465835607
ko05340	Primary immunodeficiency	6/524	30/7206	0.0190255402868
ko04080	Neuroactive ligand-receptor interaction	19/524	423/7206	0.0204241403582
ko04010	MAPK signaling pathway	13/524	321/7206	0.0205196138735
ko05134	Legionellosis	11/524	74/7206	0.0208372886295
ko00260	Glycine, serine and threonine metabolism	8/524	48/7206	0.0211019862898
ko04111	Cell cycle - yeast	1/524	90/7206	0.021447018111
ko00627	Aminobenzoate degradation	3/524	9/7206	0.0230651315938
ko00930	Caprolactam degradation	3/524	9/7206	0.0230651315938
ko00561	Glycerolipid metabolism	10/524	63/7206	0.0230833555688
ko04540	Gap junction	3/524	128/7206	0.0246975453123
ko04724	Glutamatergic synapse	4/524	152/7206	0.0253127216454
ko04721	Synaptic vesicle cycle	1/524	80/7206	0.0291831439845
ko04022	cGMP-PKG signaling pathway	24/524	216/7206	0.0328943651764
ko05133	Pertussis	12/524	87/7206	0.0334884594883
ko04662	B cell receptor signaling pathway	12/524	88/7206	0.0347343627494
ko04614	Renin-angiotensin system	4/524	18/7206	0.0373374070495
ko04975	Fat digestion and absorption	6/524	35/7206	0.0383152362434
ko00020	Citrate cycle (TCA cycle)	6/524	35/7206	0.0383152362434
ko04360	Axon guidance	9/524	233/7206	0.0396946720246
ko04270	Vascular smooth muscle contraction	18/524	154/7206	0.0404163176316
ko00130	Ubiquinone and other terpenoid-quinone biosynthesis	3/524	11/7206	0.0406407055226
ko05144	Malaria	7/524	45/7206	0.0420543636912
ko00710	Carbon fixation in photosynthetic organisms	5/524	27/7206	0.0424346407091
ko04512	ECM-receptor interaction	11/524	79/7206	0.044911510041
ko04726	Serotonergic synapse	4/524	137/7206	0.0453849186576
ko00400	Phenylalanine, tyrosine and tryptophan biosynthesis	2/524	5/7206	0.0455418032929
ko00281	Geraniol degradation	2/524	5/7206	0.0455418032929
ko04114	Oocyte meiosis	4/524	139/7206	0.0458120460425
ko05100	Bacterial invasion of epithelial cells	2/524	99/7206	0.0477126775433
ko04672	Intestinal immune network for IgA production	6/524	37/7206	0.0486034472986