ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 36/342 191/7206 4.95918728938e-13 ko04512 ECM-receptor interaction 15/342 79/7206 3.46230766837e-06 ko00643 Styrene degradation 4/342 4/7206 4.98934733379e-06 ko04672 Intestinal immune network for IgA production 10/342 37/7206 5.61881320657e-06 ko04658 Th1 and Th2 cell differentiation 16/342 96/7206 9.60439390819e-06 ko05321 Inflammatory bowel disease (IBD) 11/342 56/7206 5.09623896396e-05 ko00140 Steroid hormone biosynthesis 9/342 41/7206 9.99249040764e-05 ko00350 Tyrosine metabolism 8/342 33/7206 0.000115936226358 ko05145 Toxoplasmosis 16/342 126/7206 0.000282238367093 ko04621 NOD-like receptor signaling pathway 18/342 157/7206 0.000431953455169 ko04659 Th17 cell differentiation 14/342 106/7206 0.000448508538833 ko04668 TNF signaling pathway 15/342 120/7206 0.000516242095905 ko04064 NF-kappa B signaling pathway 13/342 96/7206 0.000558983931489 ko05146 Amoebiasis 13/342 99/7206 0.000753506889978 ko04640 Hematopoietic cell lineage 10/342 64/7206 0.00077906697516 ko05323 Rheumatoid arthritis 12/342 89/7206 0.00094171343117 ko04510 Focal adhesion 23/342 240/7206 0.0016030812966 ko04380 Osteoclast differentiation 15/342 134/7206 0.00163353879002 ko04062 Chemokine signaling pathway 20/342 201/7206 0.00187069890046 ko00120 Primary bile acid biosynthesis 5/342 20/7206 0.00200824182446 ko04660 T cell receptor signaling pathway 14/342 124/7206 0.00213274449206 ko04657 IL-17 signaling pathway 11/342 87/7206 0.00257258852381 ko05164 Influenza A 17/342 167/7206 0.00259963574821 ko05140 Leishmaniasis 10/342 75/7206 0.00268544686594 ko00565 Ether lipid metabolism 7/342 42/7206 0.0032705291577 ko05161 Hepatitis B 17/342 173/7206 0.00534792442477 ko04974 Protein digestion and absorption 11/342 96/7206 0.00554517090242 ko05132 Salmonella infection 11/342 98/7206 0.00647731065089 ko05012 Parkinson's disease 1/342 155/7206 0.00705837240842 ko05162 Measles 13/342 120/7206 0.0071380505912 ko04666 Fc gamma R-mediated phagocytosis 13/342 122/7206 0.0075373570258 ko04622 RIG-I-like receptor signaling pathway 8/342 62/7206 0.0085285271404 ko05322 Systemic lupus erythematosus 1/342 151/7206 0.0103963246916 ko00590 Arachidonic acid metabolism 7/342 52/7206 0.0108220528779 ko04630 Jak-STAT signaling pathway 13/342 132/7206 0.0111652764679 ko04610 Complement and coagulation cascades 9/342 79/7206 0.01206105351 ko05340 Primary immunodeficiency 5/342 30/7206 0.012512951366 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 2/342 4/7206 0.0126441858217 ko04933 AGE-RAGE signaling pathway in diabetic complications 13/342 135/7206 0.0128429399968 ko00051 Fructose and mannose metabolism 6/342 42/7206 0.0135152596688 ko05016 Huntington's disease 3/342 215/7206 0.0136209531931 ko04151 PI3K-Akt signaling pathway 29/342 390/7206 0.014018656324 ko04120 Ubiquitin mediated proteolysis 1/342 138/7206 0.0148225282543 ko04110 Cell cycle 1/342 145/7206 0.0154727329166 ko04810 Regulation of actin cytoskeleton 21/342 264/7206 0.0176891621206 ko05410 Hypertrophic cardiomyopathy (HCM) 10/342 100/7206 0.0272612546521 ko00190 Oxidative phosphorylation 1/342 127/7206 0.0317496262982 ko05160 Hepatitis C 13/342 153/7206 0.0342690293213 ko04662 B cell receptor signaling pathway 9/342 88/7206 0.036625774434 ko04623 Cytosolic DNA-sensing pathway 5/342 41/7206 0.0431680871087 ko00360 Phenylalanine metabolism 3/342 17/7206 0.0439399553161 ko05320 Autoimmune thyroid disease 4/342 29/7206 0.0463963013244 ko00966 Glucosinolate biosynthesis 1/342 1/7206 0.0474604496254 ko00401 Novobiocin biosynthesis 1/342 1/7206 0.0474604496254 ko04650 Natural killer cell mediated cytotoxicity 9/342 97/7206 0.0487271145342