ko pathway ratio_in_study ratio_in_pop p_value ko00140 Steroid hormone biosynthesis 10/157 41/7206 1.13528412283e-08 ko00830 Retinol metabolism 10/157 42/7206 1.46242137524e-08 ko00983 Drug metabolism - other enzymes 9/157 42/7206 2.12027834148e-07 ko00350 Tyrosine metabolism 8/157 33/7206 3.71345901261e-07 ko05204 Chemical carcinogenesis 9/157 48/7206 7.13144762339e-07 ko04610 Complement and coagulation cascades 11/157 79/7206 9.32627321736e-07 ko00980 Metabolism of xenobiotics by cytochrome P450 8/157 40/7206 1.8069519616e-06 ko00591 Linoleic acid metabolism 6/157 22/7206 5.43465756653e-06 ko00260 Glycine, serine and threonine metabolism 8/157 48/7206 7.64716957286e-06 ko04976 Bile secretion 10/157 80/7206 8.03942441658e-06 ko04975 Fat digestion and absorption 7/157 35/7206 8.20845282724e-06 ko00380 Tryptophan metabolism 8/157 50/7206 1.04854284571e-05 ko00982 Drug metabolism - cytochrome P450 7/157 37/7206 1.2115752646e-05 ko00360 Phenylalanine metabolism 5/157 17/7206 2.30657587371e-05 ko00643 Styrene degradation 3/157 4/7206 3.99478720597e-05 ko04974 Protein digestion and absorption 10/157 96/7206 4.08543343595e-05 ko00120 Primary bile acid biosynthesis 5/157 20/7206 5.48103290149e-05 ko03320 PPAR signaling pathway 8/157 69/7206 0.000115023727232 ko04972 Pancreatic secretion 10/157 111/7206 0.000141127499808 ko00040 Pentose and glucuronate interconversions 5/157 26/7206 0.000209220514932 ko04973 Carbohydrate digestion and absorption 6/157 42/7206 0.00026652931491 ko00561 Glycerolipid metabolism 7/157 63/7206 0.000405161350114 ko04614 Renin-angiotensin system 4/157 18/7206 0.000522857175806 ko00950 Isoquinoline alkaloid biosynthesis 3/157 10/7206 0.00108802532194 ko00053 Ascorbate and aldarate metabolism 4/157 22/7206 0.00116785948268 ko00250 Alanine, aspartate and glutamate metabolism 5/157 38/7206 0.00129335578263 ko00340 Histidine metabolism 4/157 25/7206 0.00191957264757 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 2/157 4/7206 0.00274984962112 ko00270 Cysteine and methionine metabolism 5/157 47/7206 0.00337775122609 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/157 5/7206 0.00451756947911 ko00590 Arachidonic acid metabolism 5/157 52/7206 0.005246101373 ko00564 Glycerophospholipid metabolism 7/157 99/7206 0.00568126455191 ko00860 Porphyrin and chlorophyll metabolism 4/157 34/7206 0.00604635967916 ko00520 Amino sugar and nucleotide sugar metabolism 5/157 55/7206 0.00666558846137 ko04080 Neuroactive ligand-receptor interaction 2/157 423/7206 0.00879875675754 ko00630 Glyoxylate and dicarboxylate metabolism 4/157 38/7206 0.00899881859055 ko02010 ABC transporters 4/157 39/7206 0.0098606461033 ko00100 Steroid biosynthesis 3/157 21/7206 0.0101163096636 ko00330 Arginine and proline metabolism 5/157 61/7206 0.0102737469313 ko01230 Biosynthesis of amino acids 6/157 85/7206 0.0103279386321 ko00565 Ether lipid metabolism 4/157 42/7206 0.0127618273886 ko04920 Adipocytokine signaling pathway 6/157 89/7206 0.012786758902 ko00650 Butanoate metabolism 3/157 26/7206 0.0182710342046 ko00072 Synthesis and degradation of ketone bodies 2/157 10/7206 0.0189242046392 ko00401 Novobiocin biosynthesis 1/157 1/7206 0.0217873993894 ko05166 HTLV-I infection 1/157 292/7206 0.0219897466227 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 2/157 11/7206 0.0228024252115 ko00280 Valine, leucine and isoleucine degradation 4/157 54/7206 0.0295326601766 ko00480 Glutathione metabolism 4/157 55/7206 0.0313261559975 ko00640 Propanoate metabolism 3/157 34/7206 0.0370825414804 ko00410 beta-Alanine metabolism 3/157 35/7206 0.0399297065481 ko00500 Starch and sucrose metabolism 3/157 35/7206 0.0399297065481 ko05133 Pertussis 5/157 87/7206 0.0408337745974 ko05150 Staphylococcus aureus infection 3/157 36/7206 0.0428845774075 ko00254 Aflatoxin biosynthesis 1/157 2/7206 0.0431030660511 ko04146 Peroxisome 5/157 89/7206 0.044334858429 ko04913 Ovarian steroidogenesis 4/157 63/7206 0.0479502034101 ko04010 MAPK signaling pathway 2/157 321/7206 0.0487375535131