ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	130/919	423/7206	7.24375175333e-24
ko04724	Glutamatergic synapse	65/919	152/7206	1.27258212203e-20
ko04713	Circadian entrainment	50/919	136/7206	5.13827411935e-13
ko04020	Calcium signaling pathway	75/919	265/7206	5.92897383645e-12
ko04727	GABAergic synapse	42/919	110/7206	9.24998302338e-12
ko05032	Morphine addiction	41/919	110/7206	4.03328715208e-11
ko04728	Dopaminergic synapse	57/919	185/7206	5.9568182112e-11
ko05033	Nicotine addiction	27/919	56/7206	9.28572333614e-11
ko04744	Phototransduction	21/919	36/7206	1.12158642042e-10
ko04721	Synaptic vesicle cycle	33/919	80/7206	1.45042151425e-10
ko04726	Serotonergic synapse	46/919	137/7206	1.64100852277e-10
ko04024	cAMP signaling pathway	74/919	279/7206	3.15296763793e-10
ko04911	Insulin secretion	40/919	117/7206	1.42611054197e-09
ko04725	Cholinergic synapse	48/919	160/7206	5.06228388848e-09
ko04723	Retrograde endocannabinoid signaling	51/919	175/7206	5.61405924845e-09
ko04921	Oxytocin signaling pathway	57/919	209/7206	1.02226304163e-08
ko05322	Systemic lupus erythematosus	1/919	151/7206	3.95194703583e-08
ko04720	Long-term potentiation	33/919	99/7206	7.95724104519e-08
ko05031	Amphetamine addiction	31/919	91/7206	1.12323817541e-07
ko03010	Ribosome	1/919	129/7206	7.19528257671e-07
ko04070	Phosphatidylinositol signaling system	34/919	112/7206	8.38926124893e-07
ko03040	Spliceosome	2/919	145/7206	9.17446773709e-07
ko04970	Salivary secretion	30/919	95/7206	1.15049564111e-06
ko04261	Adrenergic signaling in cardiomyocytes	50/919	205/7206	3.51197198774e-06
ko04925	Aldosterone synthesis and secretion	31/919	105/7206	4.34035550044e-06
ko04966	Collecting duct acid secretion	13/919	26/7206	4.55215804136e-06
ko04745	Phototransduction - fly	16/919	38/7206	6.17336306033e-06
ko04730	Long-term depression	25/919	78/7206	6.63939649122e-06
ko03013	RNA transport	5/919	166/7206	1.69510038872e-05
ko04072	Phospholipase D signaling pathway	47/919	197/7206	1.73782053769e-05
ko04110	Cell cycle	4/919	145/7206	4.14415768283e-05
ko05203	Viral carcinogenesis	15/919	277/7206	6.6584623529e-05
ko04971	Gastric acid secretion	27/919	98/7206	8.37994888293e-05
ko04742	Taste transduction	19/919	61/7206	0.000129402499597
ko04022	cGMP-PKG signaling pathway	47/919	216/7206	0.000169186477519
ko05030	Cocaine addiction	21/919	73/7206	0.000250723904695
ko04014	Ras signaling pathway	56/919	279/7206	0.00045705537464
ko03008	Ribosome biogenesis in eukaryotes	1/919	79/7206	0.0004939474668
ko04964	Proximal tubule bicarbonate reclamation	11/919	29/7206	0.000530516143792
ko04710	Circadian rhythm	14/919	43/7206	0.000595292045458
ko05168	Herpes simplex infection	9/919	182/7206	0.000646634128078
ko05110	Vibrio cholerae infection	18/919	63/7206	0.00080731588437
ko04750	Inflammatory mediator regulation of TRP channels	29/919	122/7206	0.00082592766851
ko04626	Plant-pathogen interaction	8/919	18/7206	0.000911947561712
ko05224	Breast cancer	9/919	174/7206	0.00118029247455
ko04972	Pancreatic secretion	26/919	111/7206	0.00219826799226
ko04612	Antigen processing and presentation	2/919	77/7206	0.00318778430373
ko04740	Olfactory transduction	20/919	80/7206	0.00341059340928
ko04141	Protein processing in endoplasmic reticulum	11/919	184/7206	0.00342559508846
ko05169	Epstein-Barr virus infection	13/919	206/7206	0.00393997207086
ko04960	Aldosterone-regulated sodium reabsorption	12/919	41/7206	0.00396024828848
ko04922	Glucagon signaling pathway	28/919	128/7206	0.00446854303276
ko04540	Gap junction	28/919	128/7206	0.00446854303276
ko04514	Cell adhesion molecules (CAMs)	28/919	130/7206	0.00484204463384
ko04010	MAPK signaling pathway	58/919	321/7206	0.00593449867176
ko00910	Nitrogen metabolism	7/919	19/7206	0.00672770159026
ko05200	Pathways in cancer	44/919	492/7206	0.00769558982809
ko00520	Amino sugar and nucleotide sugar metabolism	1/919	55/7206	0.00776006969661
ko04924	Renin secretion	20/919	86/7206	0.00811529236637
ko05217	Basal cell carcinoma	2/919	68/7206	0.0096646540937
ko03050	Proteasome	1/919	54/7206	0.0119384712738
ko04371	Apelin signaling pathway	34/919	177/7206	0.0119592988362
ko05231	Choline metabolism in cancer	27/919	134/7206	0.0128617169196
ko05014	Amyotrophic lateral sclerosis (ALS)	17/919	74/7206	0.0131501707625
ko05164	Influenza A	11/919	167/7206	0.0132884489033
ko05130	Pathogenic Escherichia coli infection	3/919	77/7206	0.0151102177603
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/919	182/7206	0.0180448064618
ko05162	Measles	7/919	120/7206	0.0184917734945
ko04270	Vascular smooth muscle contraction	30/919	154/7206	0.0194191892034
ko05161	Hepatitis B	12/919	173/7206	0.0202823208553
ko04657	IL-17 signaling pathway	4/919	87/7206	0.0218813724483
ko04510	Focal adhesion	19/919	240/7206	0.0230312255248
ko00562	Inositol phosphate metabolism	19/919	89/7206	0.0234338521271
ko03420	Nucleotide excision repair	1/919	46/7206	0.025020278283
ko05219	Bladder cancer	1/919	48/7206	0.0263821238517
ko04120	Ubiquitin mediated proteolysis	9/919	138/7206	0.0274447881705
ko04360	Axon guidance	41/919	233/7206	0.0279600738283
ko04621	NOD-like receptor signaling pathway	11/919	157/7206	0.0287171496174
ko05131	Shigellosis	4/919	82/7206	0.0292735401993
ko04810	Regulation of actin cytoskeleton	22/919	264/7206	0.0300476087123
ko05166	HTLV-I infection	25/919	292/7206	0.0310462496865
ko04919	Thyroid hormone signaling pathway	27/919	143/7206	0.0311878088786
ko04260	Cardiac muscle contraction	20/919	98/7206	0.0312560597144
ko05205	Proteoglycans in cancer	23/919	271/7206	0.0323400216769
ko00680	Methane metabolism	9/919	34/7206	0.0328422259167
ko04550	Signaling pathways regulating pluripotency of stem cells	12/919	165/7206	0.032874863403
ko00010	Glycolysis / Gluconeogenesis	16/919	74/7206	0.0331333858976
ko00120	Primary bile acid biosynthesis	6/919	20/7206	0.0338169156738
ko04520	Adherens junction	6/919	103/7206	0.0357408894036
ko05222	Small cell lung cancer	5/919	89/7206	0.0378728676063
ko00280	Valine, leucine and isoleucine degradation	2/919	54/7206	0.0405654772802
ko04210	Apoptosis	14/919	180/7206	0.041483924166
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/919	59/7206	0.0466349133702
ko01230	Biosynthesis of amino acids	17/919	85/7206	0.0496766639353