ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03030	DNA replication	29/403	38/7206	1.84978887731e-29
ko04110	Cell cycle	52/403	145/7206	2.47652012821e-29
ko04111	Cell cycle - yeast	34/403	90/7206	2.69367290043e-20
ko03410	Base excision repair	22/403	38/7206	1.56021227986e-18
ko03040	Spliceosome	38/403	145/7206	2.45749089311e-16
ko03430	Mismatch repair	16/403	22/7206	3.76157276888e-16
ko04113	Meiosis - yeast	24/403	70/7206	1.45022479192e-13
ko03440	Homologous recombination	18/403	41/7206	1.21467608114e-12
ko03460	Fanconi anemia pathway	19/403	51/7206	9.75653178393e-12
ko03420	Nucleotide excision repair	17/403	46/7206	1.4352037623e-10
ko00240	Pyrimidine metabolism	25/403	110/7206	1.04160276635e-09
ko04144	Endocytosis	1/403	342/7206	8.41631812716e-08
ko04020	Calcium signaling pathway	1/403	265/7206	7.03362634007e-06
ko05217	Basal cell carcinoma	13/403	68/7206	8.07968161112e-05
ko04072	Phospholipase D signaling pathway	1/403	197/7206	0.000224923730401
ko04810	Regulation of actin cytoskeleton	3/403	264/7206	0.000309091537663
ko04060	Cytokine-cytokine receptor interaction	1/403	191/7206	0.000332527154902
ko03008	Ribosome biogenesis in eukaryotes	13/403	79/7206	0.000387914993718
ko03013	RNA transport	21/403	166/7206	0.00041427795469
ko05166	HTLV-I infection	31/403	292/7206	0.000584423681567
ko04723	Retrograde endocannabinoid signaling	1/403	175/7206	0.000712420221583
ko04015	Rap1 signaling pathway	4/403	278/7206	0.000733606211397
ko04115	p53 signaling pathway	12/403	74/7206	0.00073980685539
ko04151	PI3K-Akt signaling pathway	8/403	390/7206	0.000887379856075
ko04218	Cellular senescence	21/403	177/7206	0.00122103987024
ko04062	Chemokine signaling pathway	2/403	201/7206	0.00149811388712
ko04114	Oocyte meiosis	17/403	139/7206	0.00214155804437
ko04270	Vascular smooth muscle contraction	1/403	154/7206	0.00223202633304
ko05012	Parkinson's disease	1/403	155/7206	0.0022384135209
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/403	182/7206	0.0029894755453
ko04724	Glutamatergic synapse	1/403	152/7206	0.00343696057208
ko00230	Purine metabolism	21/403	194/7206	0.0036469431389
ko04022	cGMP-PKG signaling pathway	3/403	216/7206	0.0036674376345
ko04340	Hedgehog signaling pathway	9/403	58/7206	0.00453129113718
ko04261	Adrenergic signaling in cardiomyocytes	3/403	205/7206	0.00495566895154
ko04910	Insulin signaling pathway	2/403	172/7206	0.00623542733891
ko04380	Osteoclast differentiation	1/403	134/7206	0.00693640754454
ko04726	Serotonergic synapse	1/403	137/7206	0.00717638831325
ko04024	cAMP signaling pathway	6/403	279/7206	0.00736823422678
ko04014	Ras signaling pathway	6/403	279/7206	0.00736823422678
ko04725	Cholinergic synapse	2/403	160/7206	0.00863228408876
ko05142	Chagas disease (American trypanosomiasis)	1/403	130/7206	0.0104394443344
ko04514	Cell adhesion molecules (CAMs)	1/403	130/7206	0.0104394443344
ko05206	MicroRNAs in cancer	18/403	177/7206	0.0121319435703
ko04010	MAPK signaling pathway	8/403	321/7206	0.0121464812599
ko05160	Hepatitis C	2/403	153/7206	0.012226310743
ko04728	Dopaminergic synapse	3/403	185/7206	0.0136713486006
ko04921	Oxytocin signaling pathway	4/403	209/7206	0.0137901615259
ko05152	Tuberculosis	3/403	187/7206	0.0140072741154
ko04510	Focal adhesion	5/403	240/7206	0.0140173423862
ko04668	TNF signaling pathway	1/403	120/7206	0.0146311360873
ko04750	Inflammatory mediator regulation of TRP channels	1/403	122/7206	0.0149347681735
ko05222	Small cell lung cancer	11/403	89/7206	0.01615763334
ko04670	Leukocyte transendothelial migration	2/403	151/7206	0.0178989067797
ko04530	Tight junction	5/403	228/7206	0.0184463294056
ko03015	mRNA surveillance pathway	11/403	93/7206	0.0187838883979
ko04371	Apelin signaling pathway	3/403	177/7206	0.0188375451503
ko04972	Pancreatic secretion	1/403	111/7206	0.0210140339039
ko04727	GABAergic synapse	1/403	110/7206	0.0210249300403
ko05032	Morphine addiction	1/403	110/7206	0.0210249300403
ko04070	Phosphatidylinositol signaling system	1/403	112/7206	0.0210708448185
ko04330	Notch signaling pathway	8/403	62/7206	0.0213021140203
ko04911	Insulin secretion	1/403	117/7206	0.0223745926919
ko04520	Adherens junction	1/403	103/7206	0.0303401837343
ko04925	Aldosterone synthesis and secretion	1/403	105/7206	0.0304517791473
ko04659	Th17 cell differentiation	1/403	106/7206	0.03064772064
ko01521	EGFR tyrosine kinase inhibitor resistance	1/403	106/7206	0.03064772064
ko04915	Estrogen signaling pathway	2/403	131/7206	0.0341522294764
ko04630	Jak-STAT signaling pathway	2/403	132/7206	0.0341989232971
ko04713	Circadian entrainment	2/403	136/7206	0.0351923707274
ko04722	Neurotrophin signaling pathway	3/403	160/7206	0.0353175634619
ko04931	Insulin resistance	2/403	137/7206	0.0356420556189
ko04611	Platelet activation	3/403	163/7206	0.036038465796
ko04550	Signaling pathways regulating pluripotency of stem cells	16/403	165/7206	0.0368619865642
ko04971	Gastric acid secretion	1/403	98/7206	0.0439216282531
ko00564	Glycerophospholipid metabolism	1/403	99/7206	0.0442262117067
ko05146	Amoebiasis	1/403	99/7206	0.0442262117067
ko04914	Progesterone-mediated oocyte maturation	11/403	104/7206	0.0476434932174
ko04660	T cell receptor signaling pathway	2/403	124/7206	0.0477902628666
ko05145	Toxoplasmosis	2/403	126/7206	0.0481171968661
ko04540	Gap junction	2/403	128/7206	0.0488672098832