ko pathway ratio_in_study ratio_in_pop p_value ko04360 Axon guidance 40/217 233/7206 5.03824506087e-20 ko04550 Signaling pathways regulating pluripotency of stem cells 29/217 165/7206 5.71215736951e-15 ko04390 Hippo signaling pathway 30/217 188/7206 2.80460602373e-14 ko05217 Basal cell carcinoma 19/217 68/7206 5.18197047934e-14 ko05200 Pathways in cancer 42/217 492/7206 3.9365888008e-10 ko04340 Hedgehog signaling pathway 14/217 58/7206 1.04268289022e-09 ko05224 Breast cancer 23/217 174/7206 1.70282243596e-09 ko04310 Wnt signaling pathway 20/217 181/7206 4.26213206766e-07 ko04391 Hippo signaling pathway - fly 13/217 90/7206 2.47469021858e-06 ko04080 Neuroactive ligand-receptor interaction 1/217 423/7206 4.78909962253e-05 ko05205 Proteoglycans in cancer 21/217 271/7206 6.074308308e-05 ko04350 TGF-beta signaling pathway 11/217 103/7206 0.000250767982935 ko05166 HTLV-I infection 21/217 292/7206 0.000285869721307 ko04520 Adherens junction 10/217 103/7206 0.00101834495225 ko04916 Melanogenesis 12/217 142/7206 0.00113628150737 ko04392 Hippo signaling pathway -multiple species 5/217 31/7206 0.00211965638891 ko00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 4/217 19/7206 0.00217153227561 ko04330 Notch signaling pathway 7/217 62/7206 0.00245457995353 ko04150 mTOR signaling pathway 13/217 184/7206 0.00358876984416 ko04020 Calcium signaling pathway 1/217 265/7206 0.00504034117257 ko05222 Small cell lung cancer 8/217 89/7206 0.00517196215062 ko04341 Hedgehog signaling pathway - fly 5/217 38/7206 0.00528012999547 ko04151 PI3K-Akt signaling pathway 21/217 390/7206 0.0087985418932 ko04512 ECM-receptor interaction 7/217 79/7206 0.00941820909124 ko05034 Alcoholism 1/217 238/7206 0.0106141409182 ko04919 Thyroid hormone signaling pathway 10/217 143/7206 0.0108927546068 ko05206 MicroRNAs in cancer 12/217 177/7206 0.0111813682469 ko04015 Rap1 signaling pathway 16/217 278/7206 0.0112466659407 ko01521 EGFR tyrosine kinase inhibitor resistance 8/217 106/7206 0.014323920524 ko05210 Colorectal cancer 7/217 86/7206 0.0146441571933 ko04510 Focal adhesion 14/217 240/7206 0.0183567772263 ko04921 Oxytocin signaling pathway 1/217 209/7206 0.0219849384148 ko04530 Tight junction 13/217 228/7206 0.0269205715398 ko05010 Alzheimer's disease 1/217 202/7206 0.0328545536884 ko00515 Mannose type O-glycan biosynthesis 3/217 25/7206 0.0380384858563 ko05212 Pancreatic cancer 6/217 83/7206 0.0385065678947 ko04210 Apoptosis 1/217 180/7206 0.04532953021 ko04141 Protein processing in endoplasmic reticulum 1/217 184/7206 0.0458390597232