ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	157/1044	423/7206	4.91302406604e-33
ko05033	Nicotine addiction	42/1044	56/7206	2.09701355858e-24
ko04724	Glutamatergic synapse	73/1044	152/7206	2.18290392346e-23
ko04713	Circadian entrainment	62/1044	136/7206	1.41884506885e-18
ko05032	Morphine addiction	54/1044	110/7206	3.98024352807e-18
ko04728	Dopaminergic synapse	74/1044	185/7206	6.114504006e-18
ko04727	GABAergic synapse	53/1044	110/7206	2.34058213902e-17
ko04725	Cholinergic synapse	63/1044	160/7206	4.75744560914e-15
ko04744	Phototransduction	26/1044	36/7206	6.87635464948e-15
ko04721	Synaptic vesicle cycle	40/1044	80/7206	4.31672500064e-14
ko04911	Insulin secretion	49/1044	117/7206	3.53446785319e-13
ko04723	Retrograde endocannabinoid signaling	63/1044	175/7206	6.12543916018e-13
ko04742	Taste transduction	32/1044	61/7206	2.88766774662e-12
ko04024	cAMP signaling pathway	85/1044	279/7206	3.45333849318e-12
ko04740	Olfactory transduction	37/1044	80/7206	8.02932295554e-12
ko04726	Serotonergic synapse	49/1044	137/7206	3.14715990896e-10
ko05203	Viral carcinogenesis	9/1044	277/7206	5.01455502841e-10
ko04261	Adrenergic signaling in cardiomyocytes	62/1044	205/7206	4.15060787346e-09
ko04921	Oxytocin signaling pathway	61/1044	209/7206	3.51980347839e-08
ko05031	Amphetamine addiction	34/1044	91/7206	4.84965562549e-08
ko03040	Spliceosome	2/1044	145/7206	6.4407026255e-08
ko04970	Salivary secretion	34/1044	95/7206	1.64480928788e-07
ko05164	Influenza A	4/1044	167/7206	1.69483045353e-07
ko04020	Calcium signaling pathway	70/1044	265/7206	2.62148196218e-07
ko04360	Axon guidance	62/1044	233/7206	9.43873491209e-07
ko04022	cGMP-PKG signaling pathway	58/1044	216/7206	1.65723908906e-06
ko04120	Ubiquitin mediated proteolysis	3/1044	138/7206	1.87738003893e-06
ko05168	Herpes simplex infection	7/1044	182/7206	3.31238815996e-06
ko04060	Cytokine-cytokine receptor interaction	8/1044	191/7206	5.36380467254e-06
ko03013	RNA transport	6/1044	166/7206	5.79776265674e-06
ko04514	Cell adhesion molecules (CAMs)	39/1044	130/7206	6.2487444388e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	26/1044	74/7206	6.90615354694e-06
ko04720	Long-term potentiation	32/1044	99/7206	7.88251957707e-06
ko05322	Systemic lupus erythematosus	5/1044	151/7206	1.02827392305e-05
ko04964	Proximal tubule bicarbonate reclamation	14/1044	29/7206	1.51630553125e-05
ko04924	Renin secretion	28/1044	86/7206	1.75704453819e-05
ko05030	Cocaine addiction	25/1044	73/7206	2.75067197643e-05
ko04976	Bile secretion	26/1044	80/7206	3.69480017045e-05
ko04141	Protein processing in endoplasmic reticulum	9/1044	184/7206	4.42400235881e-05
ko04974	Protein digestion and absorption	29/1044	96/7206	6.06095176137e-05
ko04925	Aldosterone synthesis and secretion	31/1044	105/7206	6.27697798275e-05
ko04621	NOD-like receptor signaling pathway	7/1044	157/7206	7.72707629304e-05
ko04512	ECM-receptor interaction	25/1044	79/7206	8.16591680075e-05
ko05162	Measles	4/1044	120/7206	0.000109910086638
ko04971	Gastric acid secretion	29/1044	98/7206	0.000115552920391
ko04610	Complement and coagulation cascades	1/1044	79/7206	0.000135436054667
ko03008	Ribosome biogenesis in eukaryotes	1/1044	79/7206	0.000135436054667
ko04730	Long-term depression	24/1044	78/7206	0.000242115495721
ko04010	MAPK signaling pathway	70/1044	321/7206	0.0003284609763
ko04745	Phototransduction - fly	14/1044	38/7206	0.000529140251667
ko04966	Collecting duct acid secretion	11/1044	26/7206	0.000533657560288
ko04972	Pancreatic secretion	30/1044	111/7206	0.00054316759931
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/1044	79/7206	0.000634883209521
ko05169	Epstein-Barr virus infection	14/1044	206/7206	0.000837887542405
ko00561	Glycerolipid metabolism	1/1044	63/7206	0.000964992321152
ko04146	Peroxisome	3/1044	89/7206	0.00118762994572
ko05166	HTLV-I infection	24/1044	292/7206	0.00120641024781
ko00564	Glycerophospholipid metabolism	4/1044	99/7206	0.00133369771008
ko05140	Leishmaniasis	2/1044	75/7206	0.0013868009782
ko04540	Gap junction	32/1044	128/7206	0.00139908162686
ko00240	Pyrimidine metabolism	5/1044	110/7206	0.00145432589566
ko00330	Arginine and proline metabolism	1/1044	61/7206	0.00146671062905
ko05205	Proteoglycans in cancer	22/1044	271/7206	0.00149411588341
ko04064	NF-kappa B signaling pathway	4/1044	96/7206	0.00189045639645
ko04260	Cardiac muscle contraction	26/1044	98/7206	0.00202240915818
ko04214	Apoptosis - fly	2/1044	72/7206	0.00202274663946
ko04151	PI3K-Akt signaling pathway	78/1044	390/7206	0.00234012950998
ko05161	Hepatitis B	12/1044	173/7206	0.00295560771588
ko00280	Valine, leucine and isoleucine degradation	1/1044	54/7206	0.00324268941703
ko04014	Ras signaling pathway	58/1044	279/7206	0.00401643922349
ko05016	Huntington's disease	17/1044	215/7206	0.00414167605773
ko04978	Mineral absorption	13/1044	40/7206	0.00496168830735
ko04612	Antigen processing and presentation	3/1044	77/7206	0.00497980187426
ko04110	Cell cycle	10/1044	145/7206	0.00597885259258
ko04640	Hematopoietic cell lineage	2/1044	64/7206	0.00638436693665
ko04371	Apelin signaling pathway	39/1044	177/7206	0.00650069193628
ko04932	Non-alcoholic fatty liver disease (NAFLD)	14/1044	182/7206	0.00728620155048
ko04142	Lysosome	11/1044	151/7206	0.00965277493479
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1044	14/7206	0.00966217264474
ko03420	Nucleotide excision repair	1/1044	46/7206	0.0107241151986
ko00260	Glycine, serine and threonine metabolism	1/1044	48/7206	0.0113899190653
ko01200	Carbon metabolism	9/1044	128/7206	0.0152414728695
ko03022	Basal transcription factors	1/1044	44/7206	0.0161371198511
ko00071	Fatty acid degradation	1/1044	45/7206	0.0167600255146
ko00480	Glutathione metabolism	2/1044	55/7206	0.0191132695523
ko05321	Inflammatory bowel disease (IBD)	2/1044	56/7206	0.0198126279312
ko04657	IL-17 signaling pathway	5/1044	87/7206	0.0200880733804
ko01524	Platinum drug resistance	4/1044	76/7206	0.0203674570752
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1044	40/7206	0.0236255891686
ko04630	Jak-STAT signaling pathway	10/1044	132/7206	0.0237191329741
ko00983	Drug metabolism - other enzymes	1/1044	42/7206	0.0246469992852
ko04668	TNF signaling pathway	9/1044	120/7206	0.0257972050008
ko05131	Shigellosis	5/1044	82/7206	0.0266041971002
ko04137	Mitophagy - animal	5/1044	82/7206	0.0266041971002
ko03018	RNA degradation	5/1044	84/7206	0.0273495588271
ko00590	Arachidonic acid metabolism	2/1044	52/7206	0.027412163425
ko04622	RIG-I-like receptor signaling pathway	3/1044	62/7206	0.0281879925269
ko05215	Prostate cancer	8/1044	111/7206	0.028610272543
ko04930	Type II diabetes mellitus	14/1044	54/7206	0.0297501349281
ko04620	Toll-like receptor signaling pathway	7/1044	100/7206	0.0310660349245
ko00982	Drug metabolism - cytochrome P450	1/1044	37/7206	0.0349763025673
ko03410	Base excision repair	1/1044	38/7206	0.0351857053478
ko04626	Plant-pathogen interaction	6/1044	18/7206	0.0358435969815
ko04217	Necroptosis	16/1044	178/7206	0.0396055519879
ko00380	Tryptophan metabolism	2/1044	50/7206	0.0403762380441
ko05414	Dilated cardiomyopathy	24/1044	112/7206	0.0418779000822
ko05110	Vibrio cholerae infection	15/1044	63/7206	0.0459047980638
ko04391	Hippo signaling pathway - fly	20/1044	90/7206	0.0482836010607
ko05012	Parkinson's disease	14/1044	155/7206	0.0499672673813