ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	57/452	152/7206	1.34324080754e-30
ko04080	Neuroactive ligand-receptor interaction	85/452	423/7206	2.14750417874e-23
ko05033	Nicotine addiction	29/452	56/7206	8.54494545168e-21
ko04713	Circadian entrainment	39/452	136/7206	1.71867239827e-16
ko04727	GABAergic synapse	35/452	110/7206	1.7781548227e-16
ko04723	Retrograde endocannabinoid signaling	44/452	175/7206	4.16918726991e-16
ko04728	Dopaminergic synapse	44/452	185/7206	3.81469831767e-15
ko05032	Morphine addiction	33/452	110/7206	9.33534046265e-15
ko04720	Long-term potentiation	31/452	99/7206	1.65837057736e-14
ko04020	Calcium signaling pathway	51/452	265/7206	2.05289834746e-13
ko04911	Insulin secretion	31/452	117/7206	2.50460600872e-12
ko04024	cAMP signaling pathway	49/452	279/7206	2.1552858241e-11
ko05031	Amphetamine addiction	26/452	91/7206	2.4033084531e-11
ko04726	Serotonergic synapse	31/452	137/7206	2.05855434246e-10
ko04921	Oxytocin signaling pathway	39/452	209/7206	4.37241867304e-10
ko04721	Synaptic vesicle cycle	22/452	80/7206	1.9037455143e-09
ko05014	Amyotrophic lateral sclerosis (ALS)	20/452	74/7206	1.45641197683e-08
ko04261	Adrenergic signaling in cardiomyocytes	35/452	205/7206	3.91616090803e-08
ko04725	Cholinergic synapse	30/452	160/7206	4.36684993094e-08
ko04010	MAPK signaling pathway	45/452	321/7206	2.19805661321e-07
ko04970	Salivary secretion	21/452	95/7206	2.7934529143e-07
ko04925	Aldosterone synthesis and secretion	22/452	105/7206	3.92745769695e-07
ko04730	Long-term depression	18/452	78/7206	1.02253973718e-06
ko04742	Taste transduction	15/452	61/7206	3.51705627365e-06
ko04971	Gastric acid secretion	19/452	98/7206	8.2116524111e-06
ko05030	Cocaine addiction	16/452	73/7206	8.34521022215e-06
ko04972	Pancreatic secretion	20/452	111/7206	1.50550033491e-05
ko04514	Cell adhesion molecules (CAMs)	22/452	130/7206	1.60620557268e-05
ko04072	Phospholipase D signaling pathway	28/452	197/7206	3.71570288919e-05
ko04022	cGMP-PKG signaling pathway	30/452	216/7206	3.94341315324e-05
ko04070	Phosphatidylinositol signaling system	19/452	112/7206	5.85694892159e-05
ko04750	Inflammatory mediator regulation of TRP channels	19/452	122/7206	0.000190639200933
ko04260	Cardiac muscle contraction	16/452	98/7206	0.000350262396851
ko05203	Viral carcinogenesis	5/452	277/7206	0.000563794089578
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	13/452	79/7206	0.00114366041137
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/452	14/7206	0.00118387072367
ko03040	Spliceosome	1/452	145/7206	0.00149809555543
ko05414	Dilated cardiomyopathy	16/452	112/7206	0.00222948729224
ko03013	RNA transport	2/452	166/7206	0.00299334550208
ko05164	Influenza A	2/452	167/7206	0.00303877254254
ko04961	Endocrine and other factor-regulated calcium reabsorption	10/452	59/7206	0.00332959919326
ko04740	Olfactory transduction	12/452	80/7206	0.00389829087386
ko05168	Herpes simplex infection	3/452	182/7206	0.00485065034379
ko04915	Estrogen signaling pathway	17/452	131/7206	0.00512592551607
ko04930	Type II diabetes mellitus	9/452	54/7206	0.0058923529337
ko04745	Phototransduction - fly	7/452	38/7206	0.00842831625429
ko04110	Cell cycle	2/452	145/7206	0.00853220621189
ko04012	ErbB signaling pathway	14/452	109/7206	0.0087003790574
ko04918	Thyroid hormone synthesis	12/452	86/7206	0.01072204337
ko05231	Choline metabolism in cancer	16/452	134/7206	0.0109901558541
ko05010	Alzheimer's disease	22/452	202/7206	0.0112573458764
ko04014	Ras signaling pathway	28/452	279/7206	0.0115629973126
ko04144	Endocytosis	33/452	342/7206	0.011655945743
ko04151	PI3K-Akt signaling pathway	13/452	390/7206	0.012949524936
ko04540	Gap junction	15/452	128/7206	0.0160328293535
ko04630	Jak-STAT signaling pathway	2/452	132/7206	0.0171185861209
ko04360	Axon guidance	24/452	233/7206	0.0182736649913
ko05169	Epstein-Barr virus infection	5/452	206/7206	0.018474505173
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/452	182/7206	0.0188385917863
ko04114	Oocyte meiosis	16/452	139/7206	0.019331965373
ko04924	Renin secretion	11/452	86/7206	0.021667415117
ko04912	GnRH signaling pathway	14/452	122/7206	0.023302511988
ko04666	Fc gamma R-mediated phagocytosis	14/452	122/7206	0.023302511988
ko00562	Inositol phosphate metabolism	11/452	89/7206	0.0257383097201
ko00512	Mucin type O-glycan biosynthesis	5/452	29/7206	0.0323235561482
ko04964	Proximal tubule bicarbonate reclamation	5/452	29/7206	0.0323235561482
ko05410	Hypertrophic cardiomyopathy (HCM)	12/452	100/7206	0.0334302838982
ko04550	Signaling pathways regulating pluripotency of stem cells	4/452	165/7206	0.0342173990678
ko05162	Measles	2/452	120/7206	0.0342321749525
ko04371	Apelin signaling pathway	18/452	177/7206	0.0396587019973
ko04960	Aldosterone-regulated sodium reabsorption	6/452	41/7206	0.0409304801424
ko04015	Rap1 signaling pathway	26/452	278/7206	0.0420904512953
ko00513	Various types of N-glycan biosynthesis	6/452	42/7206	0.0453311707031
ko04973	Carbohydrate digestion and absorption	6/452	42/7206	0.0453311707031