ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	156/877	423/7206	3.44576618923e-42
ko04724	Glutamatergic synapse	66/877	152/7206	1.63849784948e-22
ko05033	Nicotine addiction	38/877	56/7206	2.04568141104e-22
ko04721	Synaptic vesicle cycle	44/877	80/7206	2.01296172869e-20
ko05032	Morphine addiction	50/877	110/7206	2.38249086899e-18
ko04728	Dopaminergic synapse	66/877	185/7206	4.2684640871e-17
ko04727	GABAergic synapse	47/877	110/7206	5.19550593703e-16
ko04713	Circadian entrainment	53/877	136/7206	7.99936047933e-16
ko04723	Retrograde endocannabinoid signaling	59/877	175/7206	3.96035058949e-14
ko04024	cAMP signaling pathway	78/877	279/7206	3.65351597846e-13
ko04725	Cholinergic synapse	54/877	160/7206	4.72548547622e-13
ko04911	Insulin secretion	43/877	117/7206	4.73344003449e-12
ko04921	Oxytocin signaling pathway	61/877	209/7206	1.91434217052e-11
ko04726	Serotonergic synapse	46/877	137/7206	3.25714170386e-11
ko05031	Amphetamine addiction	35/877	91/7206	1.09165610592e-10
ko04020	Calcium signaling pathway	70/877	265/7206	1.47401387641e-10
ko04742	Taste transduction	26/877	61/7206	2.09247329082e-09
ko04966	Collecting duct acid secretion	16/877	26/7206	3.30422645173e-09
ko04970	Salivary secretion	33/877	95/7206	7.83519939084e-09
ko04261	Adrenergic signaling in cardiomyocytes	53/877	205/7206	5.04888971063e-08
ko05322	Systemic lupus erythematosus	1/877	151/7206	9.70451737167e-08
ko03040	Spliceosome	1/877	145/7206	2.25044469951e-07
ko04720	Long-term potentiation	31/877	99/7206	3.3141125221e-07
ko05203	Viral carcinogenesis	10/877	277/7206	7.48273668611e-07
ko04971	Gastric acid secretion	30/877	98/7206	8.82086080956e-07
ko04925	Aldosterone synthesis and secretion	31/877	105/7206	1.39340671699e-06
ko05164	Influenza A	3/877	167/7206	1.64911000689e-06
ko05030	Cocaine addiction	24/877	73/7206	2.69537215797e-06
ko04120	Ubiquitin mediated proteolysis	2/877	138/7206	4.77446881727e-06
ko04924	Renin secretion	26/877	86/7206	6.07660394601e-06
ko05168	Herpes simplex infection	5/877	182/7206	8.78318935777e-06
ko05110	Vibrio cholerae infection	21/877	63/7206	8.85015029594e-06
ko04626	Plant-pathogen interaction	10/877	18/7206	1.18252627373e-05
ko04060	Cytokine-cytokine receptor interaction	6/877	191/7206	1.48678380961e-05
ko04745	Phototransduction - fly	15/877	38/7206	1.73061579147e-05
ko04972	Pancreatic secretion	30/877	111/7206	2.28855667811e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	22/877	74/7206	4.16893960379e-05
ko05166	HTLV-I infection	15/877	292/7206	5.07229776901e-05
ko04022	cGMP-PKG signaling pathway	46/877	216/7206	0.000118360862358
ko04730	Long-term depression	22/877	78/7206	0.00013829100502
ko04964	Proximal tubule bicarbonate reclamation	11/877	29/7206	0.000351771945161
ko05169	Epstein-Barr virus infection	10/877	206/7206	0.000481359884202
ko04510	Focal adhesion	13/877	240/7206	0.000576344232015
ko05205	Proteoglycans in cancer	16/877	271/7206	0.000620238990371
ko03013	RNA transport	7/877	166/7206	0.000665989114862
ko04744	Phototransduction	12/877	36/7206	0.000752834972839
ko04540	Gap junction	29/877	128/7206	0.000865199091409
ko04514	Cell adhesion molecules (CAMs)	29/877	130/7206	0.000992394379212
ko04010	MAPK signaling pathway	59/877	321/7206	0.00114784452376
ko04110	Cell cycle	6/877	145/7206	0.00122057817318
ko04621	NOD-like receptor signaling pathway	7/877	157/7206	0.00124532302931
ko04740	Olfactory transduction	20/877	80/7206	0.0014863165128
ko04260	Cardiac muscle contraction	23/877	98/7206	0.00156556412429
ko05120	Epithelial cell signaling in Helicobacter pylori infection	22/877	92/7206	0.00181649819513
ko04978	Mineral absorption	12/877	40/7206	0.00211997312022
ko04550	Signaling pathways regulating pluripotency of stem cells	8/877	165/7206	0.00233750725878
ko04141	Protein processing in endoplasmic reticulum	10/877	184/7206	0.00281924723794
ko05161	Hepatitis B	9/877	173/7206	0.00299437566758
ko04630	Jak-STAT signaling pathway	6/877	132/7206	0.00439780281376
ko04612	Antigen processing and presentation	2/877	77/7206	0.004751280622
ko03008	Ribosome biogenesis in eukaryotes	2/877	79/7206	0.00483070817401
ko04070	Phosphatidylinositol signaling system	24/877	112/7206	0.00507362331556
ko04330	Notch signaling pathway	1/877	62/7206	0.00540851741322
ko05140	Leishmaniasis	2/877	75/7206	0.0068940338833
ko01524	Platinum drug resistance	2/877	76/7206	0.0070448037226
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/877	182/7206	0.00797273574652
ko05215	Prostate cancer	5/877	111/7206	0.00826761365619
ko04922	Glucagon signaling pathway	26/877	128/7206	0.00874889623828
ko04976	Bile secretion	18/877	80/7206	0.00875462525938
ko04214	Apoptosis - fly	2/877	72/7206	0.00999603085276
ko04915	Estrogen signaling pathway	26/877	131/7206	0.0100086361106
ko00310	Lysine degradation	2/877	73/7206	0.0102667998955
ko04371	Apelin signaling pathway	33/877	177/7206	0.0103251004201
ko05220	Chronic myeloid leukemia	3/877	85/7206	0.0111195952182
ko04064	NF-kappa B signaling pathway	4/877	96/7206	0.0113332219557
ko00280	Valine, leucine and isoleucine degradation	1/877	54/7206	0.0117496785957
ko05321	Inflammatory bowel disease (IBD)	1/877	56/7206	0.0119828552825
ko05323	Rheumatoid arthritis	19/877	89/7206	0.01318456087
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/877	59/7206	0.0139632915557
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/877	79/7206	0.0151842086815
ko04750	Inflammatory mediator regulation of TRP channels	24/877	122/7206	0.0165669082348
ko00680	Methane metabolism	9/877	34/7206	0.0175741714245
ko04011	MAPK signaling pathway - yeast	1/877	53/7206	0.0178415062557
ko04014	Ras signaling pathway	47/877	279/7206	0.0191733383255
ko04145	Phagosome	30/877	162/7206	0.0199868683854
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/877	14/7206	0.0205859757385
ko00910	Nitrogen metabolism	6/877	19/7206	0.0214031101782
ko04350	TGF-beta signaling pathway	5/877	103/7206	0.021419536324
ko05222	Small cell lung cancer	4/877	89/7206	0.0216239269193
ko04933	AGE-RAGE signaling pathway in diabetic complications	8/877	135/7206	0.0231389307561
ko04360	Axon guidance	40/877	233/7206	0.0243716214504
ko05219	Bladder cancer	1/877	48/7206	0.0254427265339
ko05146	Amoebiasis	5/877	99/7206	0.0288032155063
ko04611	Platelet activation	11/877	163/7206	0.0290514531508
ko04657	IL-17 signaling pathway	4/877	87/7206	0.0301723895912
ko05200	Pathways in cancer	45/877	492/7206	0.0321259686196
ko05418	Fluid shear stress and atherosclerosis	12/877	173/7206	0.033379047712
ko04668	TNF signaling pathway	7/877	120/7206	0.0333999442992
ko05016	Huntington's disease	16/877	215/7206	0.0334110432199
ko04072	Phospholipase D signaling pathway	34/877	197/7206	0.034927718145
ko01521	EGFR tyrosine kinase inhibitor resistance	6/877	106/7206	0.0358251665773
ko00071	Fatty acid degradation	1/877	45/7206	0.0374648439857
ko04210	Apoptosis	13/877	180/7206	0.037591755956
ko03420	Nucleotide excision repair	1/877	46/7206	0.0381819999861
ko05212	Pancreatic cancer	4/877	83/7206	0.0409409644977
ko04270	Vascular smooth muscle contraction	27/877	154/7206	0.0457547048412