ko pathway ratio_in_study ratio_in_pop p_value ko04013 MAPK signaling pathway - fly 8/80 115/7206 3.67005389173e-05 ko04722 Neurotrophin signaling pathway 8/80 160/7206 0.000370212578203 ko04910 Insulin signaling pathway 8/80 172/7206 0.000600734115206 ko05206 MicroRNAs in cancer 8/80 177/7206 0.000725980176214 ko05100 Bacterial invasion of epithelial cells 6/80 99/7206 0.00076421070938 ko04114 Oocyte meiosis 7/80 139/7206 0.000839431803156 ko04921 Oxytocin signaling pathway 8/80 209/7206 0.00211447103073 ko05418 Fluid shear stress and atherosclerosis 7/80 173/7206 0.00296280971628 ko04391 Hippo signaling pathway - fly 5/80 90/7206 0.00312900523189 ko04015 Rap1 signaling pathway 9/80 278/7206 0.00349251658806 ko04072 Phospholipase D signaling pathway 7/80 197/7206 0.00604107323369 ko05169 Epstein-Barr virus infection 7/80 206/7206 0.00766471017584 ko04810 Regulation of actin cytoskeleton 8/80 264/7206 0.00864321046531 ko04152 AMPK signaling pathway 6/80 161/7206 0.008727953935 ko05014 Amyotrophic lateral sclerosis (ALS) 4/80 74/7206 0.00900318409431 ko03013 RNA transport 6/80 166/7206 0.0100678413779 ko05130 Pathogenic Escherichia coli infection 4/80 77/7206 0.0103279579703 ko05214 Glioma 4/80 79/7206 0.0112778521947 ko04211 Longevity regulating pathway 5/80 123/7206 0.0115923274605 ko05131 Shigellosis 4/80 82/7206 0.0128055910022 ko04144 Endocytosis 9/80 342/7206 0.0130414871079 ko04218 Cellular senescence 6/80 177/7206 0.0135223371531 ko04922 Glucagon signaling pathway 5/80 128/7206 0.0136007117555 ko04915 Estrogen signaling pathway 5/80 131/7206 0.0149123272909 ko05210 Colorectal cancer 4/80 86/7206 0.0150401467486 ko05133 Pertussis 4/80 87/7206 0.0156348784883 ko04626 Plant-pathogen interaction 2/80 18/7206 0.0165977496107 ko04624 Toll and Imd signaling pathway 3/80 49/7206 0.0168306085109 ko05152 Tuberculosis 6/80 187/7206 0.0173196886246 ko05031 Amphetamine addiction 4/80 91/7206 0.018161505601 ko04120 Ubiquitin mediated proteolysis 5/80 138/7206 0.0182974264201 ko04016 MAPK signaling pathway - plant 2/80 20/7206 0.0203190906052 ko04011 MAPK signaling pathway - yeast 3/80 53/7206 0.0207364770255 ko05211 Renal cell carcinoma 4/80 96/7206 0.0216594807672 ko03050 Proteasome 3/80 54/7206 0.0217842734863 ko03040 Spliceosome 5/80 145/7206 0.0221570887579 ko04062 Chemokine signaling pathway 6/80 201/7206 0.0237911557764 ko04720 Long-term potentiation 4/80 99/7206 0.0239435811752 ko04350 TGF-beta signaling pathway 4/80 103/7206 0.0272092778739 ko04270 Vascular smooth muscle contraction 5/80 154/7206 0.0278520165236 ko04022 cGMP-PKG signaling pathway 6/80 216/7206 0.032351583792 ko05203 Viral carcinogenesis 7/80 277/7206 0.0335215773758 ko04071 Sphingolipid signaling pathway 5/80 162/7206 0.0336349091484 ko04014 Ras signaling pathway 7/80 279/7206 0.03466031355 ko05161 Hepatitis B 5/80 173/7206 0.0427337195849 ko04912 GnRH signaling pathway 4/80 122/7206 0.046243249005 ko04750 Inflammatory mediator regulation of TRP channels 4/80 122/7206 0.046243249005 ko04666 Fc gamma R-mediated phagocytosis 4/80 122/7206 0.046243249005 ko05034 Alcoholism 6/80 238/7206 0.0482032900847 ko04660 T cell receptor signaling pathway 4/80 124/7206 0.0485890311767 ko05134 Legionellosis 3/80 74/7206 0.048687281506