ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	102/577	423/7206	5.11337256359e-26
ko04724	Glutamatergic synapse	56/577	152/7206	4.4186935254e-24
ko04721	Synaptic vesicle cycle	40/577	80/7206	1.97538926531e-23
ko04728	Dopaminergic synapse	56/577	185/7206	2.31279516535e-19
ko05033	Nicotine addiction	27/577	56/7206	1.11744121815e-15
ko04713	Circadian entrainment	41/577	136/7206	2.20401004088e-14
ko04727	GABAergic synapse	36/577	110/7206	5.40652576141e-14
ko04723	Retrograde endocannabinoid signaling	45/577	175/7206	6.71778720988e-13
ko05032	Morphine addiction	34/577	110/7206	1.77549132844e-12
ko04725	Cholinergic synapse	42/577	160/7206	1.93767733505e-12
ko05031	Amphetamine addiction	29/577	91/7206	3.4225757262e-11
ko04911	Insulin secretion	32/577	117/7206	2.87615801087e-10
ko04726	Serotonergic synapse	33/577	137/7206	5.33351359857e-09
ko04966	Collecting duct acid secretion	13/577	26/7206	1.91360592578e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	22/577	74/7206	3.50429743955e-08
ko04024	cAMP signaling pathway	49/577	279/7206	1.06063906784e-07
ko05030	Cocaine addiction	21/577	73/7206	1.35099135571e-07
ko05110	Vibrio cholerae infection	18/577	63/7206	1.19391951676e-06
ko04720	Long-term potentiation	23/577	99/7206	2.25494968476e-06
ko04970	Salivary secretion	22/577	95/7206	3.96144509697e-06
ko04261	Adrenergic signaling in cardiomyocytes	36/577	205/7206	5.42534368179e-06
ko04921	Oxytocin signaling pathway	36/577	209/7206	1.16358533808e-05
ko05120	Epithelial cell signaling in Helicobacter pylori infection	20/577	92/7206	2.93526140823e-05
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/577	59/7206	4.29525045396e-05
ko04514	Cell adhesion molecules (CAMs)	25/577	130/7206	4.65866861911e-05
ko04020	Calcium signaling pathway	40/577	265/7206	7.26708487412e-05
ko04971	Gastric acid secretion	20/577	98/7206	7.62271361589e-05
ko03040	Spliceosome	1/577	145/7206	0.00013867523625
ko04010	MAPK signaling pathway	45/577	321/7206	0.000194227253466
ko04060	Cytokine-cytokine receptor interaction	3/577	191/7206	0.000199434061915
ko04925	Aldosterone synthesis and secretion	20/577	105/7206	0.000206585410886
ko04972	Pancreatic secretion	20/577	111/7206	0.000533223902253
ko05323	Rheumatoid arthritis	17/577	89/7206	0.000587847757113
ko05322	Systemic lupus erythematosus	2/577	151/7206	0.000660152812091
ko04540	Gap junction	22/577	128/7206	0.000722941222146
ko05164	Influenza A	3/577	167/7206	0.000807768363528
ko04742	Taste transduction	13/577	61/7206	0.000881932551117
ko05162	Measles	1/577	120/7206	0.000963155601001
ko04730	Long-term depression	15/577	78/7206	0.00113168933561
ko04360	Axon guidance	33/577	233/7206	0.0012327512907
ko05168	Herpes simplex infection	4/577	182/7206	0.00131258334589
ko04120	Ubiquitin mediated proteolysis	2/577	138/7206	0.00132797443406
ko04964	Proximal tubule bicarbonate reclamation	8/577	29/7206	0.00152328973404
ko04145	Phagosome	25/577	162/7206	0.00173461041809
ko04924	Renin secretion	16/577	86/7206	0.00186710231345
ko04022	cGMP-PKG signaling pathway	30/577	216/7206	0.00303341482486
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/577	14/7206	0.00351906391179
ko03013	RNA transport	4/577	166/7206	0.00356697698307
ko04391	Hippo signaling pathway - fly	15/577	90/7206	0.00537596179904
ko04014	Ras signaling pathway	35/577	279/7206	0.006715726011
ko04626	Plant-pathogen interaction	5/577	18/7206	0.0115218502035
ko00240	Pyrimidine metabolism	2/577	110/7206	0.0117186730947
ko04071	Sphingolipid signaling pathway	22/577	162/7206	0.0123415521096
ko00190	Oxidative phosphorylation	18/577	127/7206	0.0189763226712
ko03008	Ribosome biogenesis in eukaryotes	1/577	79/7206	0.0198925011585
ko05034	Alcoholism	29/577	238/7206	0.0205598511713
ko04510	Focal adhesion	10/577	240/7206	0.0214455353115
ko04915	Estrogen signaling pathway	18/577	131/7206	0.0216473730741
ko04744	Phototransduction	7/577	36/7206	0.0220288174569
ko05010	Alzheimer's disease	25/577	202/7206	0.0251344231775
ko04750	Inflammatory mediator regulation of TRP channels	17/577	122/7206	0.0263789482717
ko04745	Phototransduction - fly	7/577	38/7206	0.0290154220409
ko05167	Kaposi's sarcoma-associated herpesvirus infection	24/577	191/7206	0.0291336496151
ko04922	Glucagon signaling pathway	17/577	128/7206	0.032455418087
ko04976	Bile secretion	12/577	80/7206	0.0342527194
ko04260	Cardiac muscle contraction	14/577	98/7206	0.0358565621056
ko04930	Type II diabetes mellitus	9/577	54/7206	0.0370457058298
ko04141	Protein processing in endoplasmic reticulum	7/577	184/7206	0.0373613750129
ko04114	Oocyte meiosis	18/577	139/7206	0.038795831407
ko04912	GnRH signaling pathway	16/577	122/7206	0.042895413118
ko04146	Peroxisome	2/577	89/7206	0.0463540152975
ko04962	Vasopressin-regulated water reabsorption	9/577	58/7206	0.0473247744255