ko pathway ratio_in_study ratio_in_pop p_value ko04512 ECM-receptor interaction 29/276 79/7206 1.1514818249e-21 ko04510 Focal adhesion 40/276 240/7206 1.03829960718e-15 ko04151 PI3K-Akt signaling pathway 51/276 390/7206 2.72688447023e-15 ko04974 Protein digestion and absorption 25/276 96/7206 8.52574768305e-15 ko04060 Cytokine-cytokine receptor interaction 30/276 191/7206 2.50141621855e-11 ko05200 Pathways in cancer 49/276 492/7206 3.03414357529e-10 ko04933 AGE-RAGE signaling pathway in diabetic complications 21/276 135/7206 3.35724168217e-08 ko05146 Amoebiasis 17/276 99/7206 1.63312148914e-07 ko04810 Regulation of actin cytoskeleton 28/276 264/7206 7.95946167286e-07 ko05205 Proteoglycans in cancer 27/276 271/7206 4.24916228447e-06 ko05410 Hypertrophic cardiomyopathy (HCM) 15/276 100/7206 5.1698584806e-06 ko04668 TNF signaling pathway 16/276 120/7206 1.18864166192e-05 ko05166 HTLV-I infection 27/276 292/7206 2.57705667922e-05 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 12/276 79/7206 4.04894933149e-05 ko04658 Th1 and Th2 cell differentiation 13/276 96/7206 6.70977544325e-05 ko05414 Dilated cardiomyopathy 14/276 112/7206 8.65217148581e-05 ko05222 Small cell lung cancer 12/276 89/7206 0.000133378923341 ko04218 Cellular senescence 18/276 177/7206 0.000137631196572 ko04350 TGF-beta signaling pathway 13/276 103/7206 0.000139994822026 ko04380 Osteoclast differentiation 15/276 134/7206 0.000172839062664 ko05321 Inflammatory bowel disease (IBD) 9/276 56/7206 0.000242256641765 ko05145 Toxoplasmosis 14/276 126/7206 0.000306888904286 ko05224 Breast cancer 17/276 174/7206 0.000340662765502 ko04310 Wnt signaling pathway 17/276 181/7206 0.000540324832873 ko04015 Rap1 signaling pathway 23/276 278/7206 0.000578960520005 ko04640 Hematopoietic cell lineage 9/276 64/7206 0.000673767149702 ko05131 Shigellosis 10/276 82/7206 0.00107772286369 ko05142 Chagas disease (American trypanosomiasis) 13/276 130/7206 0.00136002768277 ko05144 Malaria 7/276 45/7206 0.00145694281034 ko04659 Th17 cell differentiation 11/276 106/7206 0.00233873410197 ko04390 Hippo signaling pathway 16/276 188/7206 0.00280639409596 ko04916 Melanogenesis 13/276 142/7206 0.00300665992333 ko05161 Hepatitis B 15/276 173/7206 0.00359544421763 ko04010 MAPK signaling pathway 23/276 321/7206 0.00402483265872 ko05206 MicroRNAs in cancer 15/276 177/7206 0.00406002151088 ko05212 Pancreatic cancer 9/276 83/7206 0.0042707543507 ko04611 Platelet activation 14/276 163/7206 0.00538855347803 ko05210 Colorectal cancer 9/276 86/7206 0.00540923709755 ko04657 IL-17 signaling pathway 9/276 87/7206 0.00583677851891 ko04068 FoxO signaling pathway 14/276 167/7206 0.0060726896568 ko04014 Ras signaling pathway 20/276 279/7206 0.00617809485642 ko05323 Rheumatoid arthritis 9/276 89/7206 0.00676975326119 ko00643 Styrene degradation 2/276 4/7206 0.00833282263898 ko04621 NOD-like receptor signaling pathway 13/276 157/7206 0.00907682997629 ko04672 Intestinal immune network for IgA production 5/276 37/7206 0.01269150363 ko05220 Chronic myeloid leukemia 8/276 85/7206 0.0157111897085 ko04144 Endocytosis 22/276 342/7206 0.0194277640316 ko04360 Axon guidance 16/276 233/7206 0.022193818996 ko04660 T cell receptor signaling pathway 10/276 124/7206 0.0277960208294 ko04142 Lysosome 1/276 151/7206 0.0312940285996 ko05202 Transcriptional misregulation in cancer 13/276 188/7206 0.0331877334889 ko05230 Central carbon metabolism in cancer 7/276 81/7206 0.0349481279095 ko05219 Bladder cancer 5/276 48/7206 0.0355486806347 ko00350 Tyrosine metabolism 4/276 33/7206 0.0359956358088 ko05034 Alcoholism 3/276 238/7206 0.0367619906649 ko04931 Insulin resistance 10/276 137/7206 0.0415399446004 ko05418 Fluid shear stress and atherosclerosis 12/276 173/7206 0.0420212556977 ko05217 Basal cell carcinoma 6/276 68/7206 0.0451134458398 ko05133 Pertussis 7/276 87/7206 0.048533500559