ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	154/967	423/7206	2.31777365914e-35
ko04724	Glutamatergic synapse	75/967	152/7206	4.01286391833e-27
ko05033	Nicotine addiction	42/967	56/7206	9.29450043097e-26
ko05032	Morphine addiction	58/967	110/7206	4.47046344857e-23
ko04713	Circadian entrainment	65/967	136/7206	1.19727858631e-22
ko04727	GABAergic synapse	54/967	110/7206	1.12163242532e-19
ko04728	Dopaminergic synapse	73/967	185/7206	3.02641168744e-19
ko04723	Retrograde endocannabinoid signaling	67/967	175/7206	6.09063686432e-17
ko04725	Cholinergic synapse	63/967	160/7206	1.06802103937e-16
ko04721	Synaptic vesicle cycle	40/967	80/7206	3.06891416988e-15
ko04911	Insulin secretion	47/967	117/7206	3.84514464059e-13
ko04020	Calcium signaling pathway	80/967	265/7206	4.89313145389e-13
ko04024	cAMP signaling pathway	82/967	279/7206	1.07526567428e-12
ko04726	Serotonergic synapse	48/967	137/7206	7.27381002873e-11
ko04921	Oxytocin signaling pathway	62/967	209/7206	4.03443539847e-10
ko04742	Taste transduction	28/967	61/7206	5.98893871932e-10
ko05031	Amphetamine addiction	35/967	91/7206	1.64127751442e-09
ko04970	Salivary secretion	34/967	95/7206	2.40904954939e-08
ko04720	Long-term potentiation	34/967	99/7206	7.80843638879e-08
ko04261	Adrenergic signaling in cardiomyocytes	56/967	205/7206	1.01448223064e-07
ko03040	Spliceosome	2/967	145/7206	3.8956874926e-07
ko04925	Aldosterone synthesis and secretion	34/967	105/7206	6.29256739428e-07
ko04744	Phototransduction	17/967	36/7206	9.04224098158e-07
ko05322	Systemic lupus erythematosus	3/967	151/7206	1.39086775635e-06
ko04514	Cell adhesion molecules (CAMs)	38/967	130/7206	1.63320762648e-06
ko04360	Axon guidance	58/967	233/7206	1.86328621298e-06
ko04971	Gastric acid secretion	31/967	98/7206	2.89497547337e-06
ko05030	Cocaine addiction	25/967	73/7206	4.35730197445e-06
ko05203	Viral carcinogenesis	14/967	277/7206	5.52157364008e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/967	74/7206	5.7562761457e-06
ko04010	MAPK signaling pathway	72/967	321/7206	7.24752694832e-06
ko03013	RNA transport	5/967	166/7206	7.95423517909e-06
ko04972	Pancreatic secretion	32/967	111/7206	1.55727730505e-05
ko04022	cGMP-PKG signaling pathway	52/967	216/7206	1.62882687985e-05
ko04621	NOD-like receptor signaling pathway	5/967	157/7206	2.39328738932e-05
ko05164	Influenza A	6/967	167/7206	2.68732085517e-05
ko04060	Cytokine-cytokine receptor interaction	8/967	191/7206	3.33882954957e-05
ko04740	Olfactory transduction	25/967	80/7206	3.59567787432e-05
ko05168	Herpes simplex infection	8/967	182/7206	9.20614462011e-05
ko04961	Endocrine and other factor-regulated calcium reabsorption	19/967	59/7206	0.000156244791178
ko04730	Long-term depression	23/967	78/7206	0.000162872073438
ko04120	Ubiquitin mediated proteolysis	5/967	138/7206	0.000199722744657
ko04745	Phototransduction - fly	14/967	38/7206	0.000235459234476
ko03008	Ribosome biogenesis in eukaryotes	1/967	79/7206	0.000328627146447
ko04141	Protein processing in endoplasmic reticulum	10/967	184/7206	0.000607348599984
ko04371	Apelin signaling pathway	40/967	177/7206	0.0007173597052
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/967	79/7206	0.00144561624581
ko04540	Gap junction	30/967	128/7206	0.00228948414646
ko04146	Peroxisome	3/967	89/7206	0.00255490358925
ko04014	Ras signaling pathway	55/967	279/7206	0.00295548440108
ko04964	Proximal tubule bicarbonate reclamation	10/967	29/7206	0.00323583401854
ko04072	Phospholipase D signaling pathway	41/967	197/7206	0.00393240635012
ko04064	NF-kappa B signaling pathway	4/967	96/7206	0.00395564144663
ko04630	Jak-STAT signaling pathway	7/967	132/7206	0.0041562043609
ko04750	Inflammatory mediator regulation of TRP channels	28/967	122/7206	0.00438508925647
ko05161	Hepatitis B	11/967	173/7206	0.00444843040644
ko04260	Cardiac muscle contraction	23/967	98/7206	0.00649364684837
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/967	14/7206	0.00661044019043
ko05169	Epstein-Barr virus infection	15/967	206/7206	0.00679388963288
ko04217	Necroptosis	12/967	178/7206	0.00710555119125
ko04610	Complement and coagulation cascades	3/967	79/7206	0.00734557537071
ko00590	Arachidonic acid metabolism	1/967	52/7206	0.00756505245479
ko05162	Measles	7/967	120/7206	0.0100774452586
ko05140	Leishmaniasis	3/967	75/7206	0.0104181648727
ko00240	Pyrimidine metabolism	6/967	110/7206	0.0105660432494
ko04612	Antigen processing and presentation	3/967	77/7206	0.0105703764343
ko04924	Renin secretion	20/967	86/7206	0.0106237893991
ko04710	Circadian rhythm	12/967	43/7206	0.0110623831068
ko04976	Bile secretion	19/967	80/7206	0.0120096582939
ko04915	Estrogen signaling pathway	28/967	131/7206	0.0131167665718
ko00330	Arginine and proline metabolism	2/967	61/7206	0.0135371447372
ko04930	Type II diabetes mellitus	14/967	54/7206	0.0138656314122
ko05205	Proteoglycans in cancer	23/967	271/7206	0.013909016654
ko00561	Glycerolipid metabolism	2/967	63/7206	0.01401148671
ko03420	Nucleotide excision repair	1/967	46/7206	0.0165753958544
ko04270	Vascular smooth muscle contraction	31/967	154/7206	0.0168052900772
ko05414	Dilated cardiomyopathy	24/967	112/7206	0.0169569795806
ko04070	Phosphatidylinositol signaling system	24/967	112/7206	0.0169569795806
ko05219	Bladder cancer	1/967	48/7206	0.017027566286
ko04916	Melanogenesis	29/967	142/7206	0.0177327645337
ko04110	Cell cycle	10/967	145/7206	0.0186706107771
ko04711	Circadian rhythm - fly	5/967	13/7206	0.021868833854
ko03022	Basal transcription factors	1/967	44/7206	0.0245793985163
ko05144	Malaria	1/967	45/7206	0.0251949184099
ko00071	Fatty acid degradation	1/967	45/7206	0.0251949184099
ko05016	Huntington's disease	18/967	215/7206	0.0252892204059
ko04626	Plant-pathogen interaction	6/967	18/7206	0.0254909472283
ko04210	Apoptosis	14/967	180/7206	0.0259887315179
ko00480	Glutathione metabolism	2/967	55/7206	0.027911032022
ko04668	TNF signaling pathway	8/967	120/7206	0.0295681160912
ko05166	HTLV-I infection	27/967	292/7206	0.0349335276491
ko00980	Metabolism of xenobiotics by cytochrome P450	1/967	40/7206	0.0360511641568
ko04932	Non-alcoholic fatty liver disease (NAFLD)	15/967	182/7206	0.0362269803101
ko00140	Steroid hormone biosynthesis	1/967	41/7206	0.0362754145547
ko04657	IL-17 signaling pathway	5/967	87/7206	0.0378353467186
ko05133	Pertussis	5/967	87/7206	0.0378353467186
ko04115	p53 signaling pathway	4/967	74/7206	0.0392472279873
ko01524	Platinum drug resistance	4/967	76/7206	0.0401283217828
ko04640	Hematopoietic cell lineage	3/967	64/7206	0.0407743358898
ko04923	Regulation of lipolysis in adipocytes	17/967	77/7206	0.0411852491446
ko00280	Valine, leucine and isoleucine degradation	2/967	54/7206	0.0416023033289